PROSTAGLANDIN A2

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C20H30O4
Molecular Weight	334.4498
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	2
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCC[C@H](O)\C=C\[C@H]1C=CC(=O)[C@@H]1C\C=C/CCCC(O)=O

InChI

InChIKey=MYHXHCUNDDAEOZ-FOSBLDSVSA-N

InChI=1S/C20H30O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h4,7,12-18,21H,2-3,5-6,8-11H2,1H3,(H,23,24)/b7-4-,14-12+/t16-,17-,18+/m0/s1

HIDE SMILES / InChI

Molecular Formula	C20H30O4
Molecular Weight	334.4498
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	2
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Prostaglandins antagonize fibroblast proliferation stimulated by tumor necrosis factor.	1991 Jan 31	1993070
Prostaglandin A inhibits replication of human immunodeficiency virus during acute infection.	1991 Nov	1940869
Inhibition of nuclear factor kappa B by prostaglandin A1: an effect associated with heat shock transcription factor activation.	1997 Jan 21	9012856
Stereoselective conjugation of prostaglandin A2 and prostaglandin J2 with glutathione, catalyzed by the human glutathione S-transferases A1-1, A2-2, M1a-1a, and P1-1.	1997 Mar	9084911
Prostaglandins stimulate the stress-induced synthesis of hsp27 and alpha B crystallin.	1997 Mar	9066782
Cox-dependent fatty acid metabolites cause pain through activation of the irritant receptor TRPA1.	2008 Aug 19	18687886

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:55:42 GMT 2025` Edited by `admin` on `Mon Mar 31 19:55:42 GMT 2025`
Record UNII	K6VT5BDY9E
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PROSTAGLANDIN A2

Common Name

English

MEDULLIN

Preferred Name

English

NSC-165561

Code

English

(Z)-7-((1R,2S)-2-((E)-(3S)-3-HYDROXYOCT-1-ENYL)-5-OXOCYCLOPENT-3-ENYL)HEPT-5-ENOIC ACID

Systematic Name

English

(+)-PROSTAGLANDIN A2

Common Name

English

15(S)-HYDROXY-9-OXO-5-CIS-10,13-TRANS-PROSTATRIENOIC ACID

Systematic Name

English

DINOPROSTONE IMPURITY D [EP IMPURITY]

Common Name

English

PGA2

Common Name

English

PROSTA-5,10,13-TRIEN-1-OIC ACID, 15-HYDROXY-9-OXO-, (5Z,13E,15S)-

Systematic Name

English

(5Z,13E,15S)-15-HYDROXY-9-OXOPROSTA-5, 10,13-TRIENE-1-OIC ACID

Systematic Name

English

DINOPROSTONE IMPURITY, (5Z,13E,15S)-15-HYDROXY-9-OXOPROSTA-5, 10,13-TRIENE-1-OIC ACID- [USP IMPURITY]

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID20864388