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Details

Stereochemistry ABSOLUTE
Molecular Formula 3C4H4O6.2Bi.18H2O
Molecular Weight 1186.4487
Optical Activity UNSPECIFIED
Defined Stereocenters 6 / 6
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BISMUTH TARTRATE HEXAHYDRATE

SMILES

O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.[Bi+3].[Bi+3].O[C@H]([C@@H](O)C([O-])=O)C([O-])=O.O[C@H]([C@@H](O)C([O-])=O)C([O-])=O.O[C@H]([C@@H](O)C([O-])=O)C([O-])=O

InChI

InChIKey=KQGKVNJGGQFUNF-BHYHJUIYSA-H
InChI=1S/3C4H6O6.2Bi.18H2O/c3*5-1(3(7)8)2(6)4(9)10;;;;;;;;;;;;;;;;;;;;/h3*1-2,5-6H,(H,7,8)(H,9,10);;;18*1H2/q;;;2*+3;;;;;;;;;;;;;;;;;;/p-6/t3*1-,2-;;;;;;;;;;;;;;;;;;;;/m111..................../s1

HIDE SMILES / InChI
Molecular Formula Bi
Molecular Weight 208.9804
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C4H6O6
Molecular Weight 150.0868
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Bismuth tartrate was used for the treatment of syphilis. There are death reports associated with bismuth compounds usage in syphilis treatment.

Approval Year

Unknown
139594
Doses

Doses

DosePopulationAdverse events​
0.5 g 1 times / 2 weeks multiple, intravenous
Studied dose
Dose: 0.5 g, 1 times / 2 weeks
Route: intravenous
Route: multiple
Dose: 0.5 g, 1 times / 2 weeks
Sources:
https://pubmed.ncbi.nlm.nih.gov/13058286/
unhealthy, 39 years
n = 1
Health Status: unhealthy
Condition: rheumatoid arthritis.
Age Group: 39 years
Sex: F
Population Size: 1
Sources:
https://pubmed.ncbi.nlm.nih.gov/13058286/
Other AEs: Nephrotic syndrome...
Other AEs:
Nephrotic syndrome
Sources:
https://pubmed.ncbi.nlm.nih.gov/13058286/
650 mg 1 times / day single, intravenous
Studied dose
Dose: 650 mg, 1 times / day
Route: intravenous
Route: single
Dose: 650 mg, 1 times / day
Sources:
https://pubmed.ncbi.nlm.nih.gov/18867938/
unhealthy, adult
n = 2
Health Status: unhealthy
Condition: yaws
Age Group: adult
Sex: F
Population Size: 2
Sources:
https://pubmed.ncbi.nlm.nih.gov/18867938/
Other AEs: Death...
Other AEs:
Death
Sources:
https://pubmed.ncbi.nlm.nih.gov/18867938/
AEs

AEs

AESignificanceDosePopulation
Nephrotic syndrome
0.5 g 1 times / 2 weeks multiple, intravenous
Studied dose
Dose: 0.5 g, 1 times / 2 weeks
Route: intravenous
Route: multiple
Dose: 0.5 g, 1 times / 2 weeks
Sources:
https://pubmed.ncbi.nlm.nih.gov/13058286/
unhealthy, 39 years
n = 1
Health Status: unhealthy
Condition: rheumatoid arthritis.
Age Group: 39 years
Sex: F
Population Size: 1
Sources:
https://pubmed.ncbi.nlm.nih.gov/13058286/
Death
650 mg 1 times / day single, intravenous
Studied dose
Dose: 650 mg, 1 times / day
Route: intravenous
Route: single
Dose: 650 mg, 1 times / day
Sources:
https://pubmed.ncbi.nlm.nih.gov/18867938/
unhealthy, adult
n = 2
Health Status: unhealthy
Condition: yaws
Age Group: adult
Sex: F
Population Size: 2
Sources:
https://pubmed.ncbi.nlm.nih.gov/18867938/
Sourcing

Sourcing

Vendor/AggregatorIDURL
AAA Chemistry
AR-1I0637
ABI Chem
AC1L35JZ
ABI Chem
AC1LAIJC
Amadis Chemical
A11654
Ambinter
Amb22730412
http://www.ambinter.com/reference/22730412
ChemIDplus
31586773
https://chem.nlm.nih.gov/chemidplus/id/0031586773
ChemTik
CTK4G7397
DTP/NCI
302012
http://dtp.nci.nih.gov/dtpstandard/servlet/dwindex?searchtype=NSC&outputformat=html&searchlist=302012
MP Biomedicals
212309
NovoSeek
134954
PubChem
134954
https://pubchem.ncbi.nlm.nih.gov/compound/134954
PubChem
469103
https://pubchem.ncbi.nlm.nih.gov/compound/469103
PubChem
54600498
https://pubchem.ncbi.nlm.nih.gov/compound/54600498
PubChem
76971117
https://pubchem.ncbi.nlm.nih.gov/compound/76971117
Wikidata
Q27279003
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:34:02 GMT 2023
Edited
by admin
on Fri Dec 15 15:34:02 GMT 2023
Record UNII
K4X42T019U
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BISMUTH TARTRATE HEXAHYDRATE
Common Name English
Bismuth tartrate [WHO-DD]
Common Name English
TARTARIC ACID, BISMUTH(3+) SALT, OCTADECAHYDRATE
Common Name English
BISMUTH TARTRATE
WHO-DD  
Systematic Name English
BUTANEDIOIC ACID, 2,3-DIHYDROXY- (2R,3R)-, BISMUTH(3+) SALT, OCTADECAHYDRATE (3:2:18)
Common Name English
Classification Tree Code System Code
CFR 21 CFR 331.15
Created by admin on Fri Dec 15 15:34:03 GMT 2023 , Edited by admin on Fri Dec 15 15:34:03 GMT 2023
CFR 21 CFR 331.11
Created by admin on Fri Dec 15 15:34:03 GMT 2023 , Edited by admin on Fri Dec 15 15:34:03 GMT 2023
Code System Code Type Description
MESH
C013848
Created by admin on Fri Dec 15 15:34:03 GMT 2023 , Edited by admin on Fri Dec 15 15:34:03 GMT 2023
PRIMARY
SMS_ID
300000026692
Created by admin on Fri Dec 15 15:34:03 GMT 2023 , Edited by admin on Fri Dec 15 15:34:03 GMT 2023
PRIMARY
CAS
6591-69-1
Created by admin on Fri Dec 15 15:34:03 GMT 2023 , Edited by admin on Fri Dec 15 15:34:03 GMT 2023
PRIMARY
FDA UNII
K4X42T019U
Created by admin on Fri Dec 15 15:34:03 GMT 2023 , Edited by admin on Fri Dec 15 15:34:03 GMT 2023
PRIMARY
PUBCHEM
71586900
Created by admin on Fri Dec 15 15:34:03 GMT 2023 , Edited by admin on Fri Dec 15 15:34:03 GMT 2023
PRIMARY
EPA CompTox
DTXSID80216147
Created by admin on Fri Dec 15 15:34:03 GMT 2023 , Edited by admin on Fri Dec 15 15:34:03 GMT 2023
PRIMARY
Related Record Type Details
Structure of TARTARIC ACID
PARENT -> SALT/SOLVATE
Structure of BISMUTH TARTRATE ANHYDROUS
ANHYDROUS->SOLVATE
NIH
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