Details
Stereochemistry | RACEMIC |
Molecular Formula | C16H14O5 |
Molecular Weight | 286.2794 |
Optical Activity | ( + / - ) |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=C(OC2(C)OC(=O)C3=C(O2)C=CC=C3)C=CC=C1
InChI
InChIKey=PSVDIHULUCLEJE-UHFFFAOYSA-N
InChI=1S/C16H14O5/c1-16(20-14-10-6-5-9-13(14)18-2)19-12-8-4-3-7-11(12)15(17)21-16/h3-10H,1-2H3
Molecular Formula | C16H14O5 |
Molecular Weight | 286.2794 |
Charge | 0 |
Count |
|
Stereochemistry | RACEMIC |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Optical Activity | ( + / - ) |
DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/2663163
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2663163
Guaimesal was studied for the treatment of exacerbated chronic bronchitis
Approval Year
PubMed
Title | Date | PubMed |
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[Clinical evaluation of the therapeutic efficacy of a new antiphlogistic and mucus-regulating drug, guaimesal, in acute and chronic bronchopneumopathies]. | 1984 Sep 15 |
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[Guaimesal capsules in the treatment of exacerbated chronic bronchitis]. | 1984 Sep 30 |
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Double-blind, placebo-controlled clinical evaluation of guaimesal in outpatients. | 1989 May-Jun |
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Gas chromatographic-tandem mass spectrometric determination of acetylsalicylic acid in human plasma after oral administration of low-dose aspirin and guaimesal. | 1998 May 8 |
Patents
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2663163
One hundred and forty outpatients, males and females aged 14 to 70 years, with acute febrile bronchitis, afebrile chronic bronchitis, or flares of chronic bronchitis were treated for seven days with one soft gelatin capsule (500 mg) of guaimesal thrice daily or matching placebo
Route of Administration:
Oral
Substance Class |
Chemical
Created
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admin
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Edited
Fri Dec 15 17:34:28 GMT 2023
by
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on
Fri Dec 15 17:34:28 GMT 2023
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Record UNII |
K43273G1CW
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Record Status |
Validated (UNII)
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Record Version |
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NCI_THESAURUS |
C257
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81674-79-5
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ACTIVE MOIETY |