RINDOPEPIMUT

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 20:34:19 GMT 2025` Edited by `admin` on `Tue Apr 01 20:34:19 GMT 2025`
Protein Sub Type	ANTIGEN
Sequence Origin	Other Species (select)
Sequence Type	COMPLETE
Record UNII	K3L4X0501F
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CDX-110

Preferred Name

English

RINDOPEPIMUT

Official Name

English

Rindopepimut [WHO-DD]

Common Name

English

RINDOPEPIMUT [USAN]

Common Name

English

PF-04948568

Code

English

Classification Tree Code System Code

FDA ORPHAN DRUG

249207

Created by admin on Tue Apr 01 20:34:19 GMT 2025 , Edited by admin on Tue Apr 01 20:34:19 GMT 2025

NCI_THESAURUS

C1663

Created by admin on Tue Apr 01 20:34:19 GMT 2025 , Edited by admin on Tue Apr 01 20:34:19 GMT 2025

EU-Orphan Drug

EU/3/11/923

Created by admin on Tue Apr 01 20:34:19 GMT 2025 , Edited by admin on Tue Apr 01 20:34:19 GMT 2025

Code System Code Type Description

EVMPD

SUB177845

Created by admin on Tue Apr 01 20:34:19 GMT 2025 , Edited by admin on Tue Apr 01 20:34:19 GMT 2025

PRIMARY

CAS

1108208-65-6

Created by admin on Tue Apr 01 20:34:19 GMT 2025 , Edited by admin on Tue Apr 01 20:34:19 GMT 2025

PRIMARY

ChEMBL

CHEMBL2107863

Created by admin on Tue Apr 01 20:34:19 GMT 2025 , Edited by admin on Tue Apr 01 20:34:19 GMT 2025

PRIMARY

USAN

WW-34

Created by admin on Tue Apr 01 20:34:19 GMT 2025 , Edited by admin on Tue Apr 01 20:34:19 GMT 2025

PRIMARY

FDA UNII

K3L4X0501F

Created by admin on Tue Apr 01 20:34:19 GMT 2025 , Edited by admin on Tue Apr 01 20:34:19 GMT 2025

PRIMARY

CAS

946156-74-7

Created by admin on Tue Apr 01 20:34:19 GMT 2025 , Edited by admin on Tue Apr 01 20:34:19 GMT 2025

ALTERNATIVE

DRUG BANK

DB05374

Created by admin on Tue Apr 01 20:34:19 GMT 2025 , Edited by admin on Tue Apr 01 20:34:19 GMT 2025

PRIMARY

NCI_THESAURUS

C69076

Created by admin on Tue Apr 01 20:34:19 GMT 2025 , Edited by admin on Tue Apr 01 20:34:19 GMT 2025

PRIMARY

SMS_ID

100000163538

Created by admin on Tue Apr 01 20:34:19 GMT 2025 , Edited by admin on Tue Apr 01 20:34:19 GMT 2025

PRIMARY

From	To
1_48	1_57
1_169	1_236
1_307	1_319
1_452	1_463
1_581	1_647
1_876	1_887
1_999	1_1066
1_1156	1_1162
1_1293	1_1302
1_1408	1_1475
1_1563	1_1573
1_1705	1_1716
1_1831	1_1898
1_1987	1_1993
1_2122	1_2132
1_2244	1_2311
1_2398	1_2404
1_2542	1_2552
1_2654	1_2721
1_2808	1_2814
1_2946	1_2956
1_3059	1_3126
1_3345	1_3378

Linkage Type	Residue Index
COORDINATION COMPOUND	1_2940	1_2959	1_2968	1_3069	1_3073	1_3100

Related Record Type Details


					7GY30O2Z8L

KEYHOLE LIMPET WHOLE

ORGANISM->BIOSYNTHETIC PRODUCT

Amount:


					BK69YI6V0R

EPIDERMAL GROWTH FACTOR RECEPTOR VARIANT III

TARGET->ANTIGEN

Comments:

Vaccination with rindopepimut may elicit a cytotoxic T-lymphocyte (CTL) immune response against tumor cells expressing EGFRvIII.

Amount:

Related Record Type Details


					K3L4X0501F

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION		RESIDUE_SPECIFIC	K	Amount:	RINDOPEPIMUT PEPTIDE MODIFICATION	XE2CRB6S1Q
AMINO_ACID_SUBSTITUTION	[1_2940] [1_2959] [1_2968] [1_3069] [1_3073] [1_3100]	SITE_SPECIFIC			UNSPECIFIED SUBSTANCE	c800a05e (not in database)

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL