m-Tyramine

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H11NO
Molecular Weight	137.179
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NCCC1=CC(O)=CC=C1

InChI

InChIKey=GHFGJTVYMNRGBY-UHFFFAOYSA-N

InChI=1S/C8H11NO/c9-5-4-7-2-1-3-8(10)6-7/h1-3,6,10H,4-5,9H2

HIDE SMILES / InChI

Molecular Formula	C8H11NO
Molecular Weight	137.179
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6531442 | https://www.ncbi.nlm.nih.gov/pubmed/24374199

meta-Tyramine (or m-Tyramine) is an endogenous trace amine neuromodulator, can be metabolized into dopamine via peripheral or brain CYP2D6 enzymes in humans. Meta-tyramine appears to inhibit the synthesis of dopamine.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
dopamine biosynthetic process 2 Target ID: GO:0042416 Sources: https://www.ncbi.nlm.nih.gov/pubmed/6531442	Inhibitor 8297

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed
The determination of hydroxydopamines and other trace amines in the urine of parkinsonian patients and normal controls.	1993 Nov	8255370
Determination of regional distributions of phenylethylamine and meta- and para-tyramine in rat brain regions and presence in human and dog plasma by an ultra-sensitive negative chemical ion gas chromatography-mass spectrometric (NCI-GC-MS) method.	1993 Sep	8232728

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:43:29 GMT 2023` Edited by `admin` on `Fri Dec 15 19:43:29 GMT 2023`
Record UNII	K1OA38R0EZ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

m-Tyramine

Common Name

English

Tyramine, m-

Common Name

English

2-(3-Hydroxyphenyl)ethylamine

Systematic Name

English

3-(2-Aminoethyl)phenol

Systematic Name

English

Phenol, 3-(2-aminoethyl)-

Systematic Name

English

Metatyramine

Common Name

English

Phenol, m-(2-aminoethyl)-

Systematic Name

English

Code System Code Type Description

FDA UNII

K1OA38R0EZ