3-(2-Aminoethyl)phenol hydrochloride

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H11NO.ClH
Molecular Weight	173.64
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of 3-(2-Aminoethyl)phenol hydrochloride

Structure Search

SMILES

Cl.NCCC1=CC(O)=CC=C1

InChI

InChIKey=GTIWCKXKQGMMQZ-UHFFFAOYSA-N

InChI=1S/C8H11NO.ClH/c9-5-4-7-2-1-3-8(10)6-7;/h1-3,6,10H,4-5,9H2;1H

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C8H11NO
Molecular Weight	137.179
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6531442 | https://www.ncbi.nlm.nih.gov/pubmed/24374199

meta-Tyramine (or m-Tyramine) is an endogenous trace amine neuromodulator, can be metabolized into dopamine via peripheral or brain CYP2D6 enzymes in humans. Meta-tyramine appears to inhibit the synthesis of dopamine.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
dopamine biosynthetic process 2 Target ID: GO:0042416 Sources: https://www.ncbi.nlm.nih.gov/pubmed/6531442	Inhibitor 8297

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed
The determination of hydroxydopamines and other trace amines in the urine of parkinsonian patients and normal controls.	1993 Nov	8255370
Oxidation of phenethylamine derivatives by cytochrome P450 2D6: the issue of substrate protonation in binding and catalysis.	2001 Nov 27	11714275
Solid-phase synthesis of 1-substituted tetrahydroisoquinoline derivatives employing BOC-protected tetrahydroisoquinoline carboxylic acids.	2004 Jul-Aug	15244409
Human and mouse trace amine-associated receptor 1 have distinct pharmacology towards endogenous monoamines and imidazoline receptor ligands.	2009 Oct 23	19725810

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 12:31:20 UTC 2023` Edited by `admin` on `Sat Dec 16 12:31:20 UTC 2023`
Record UNII	434H29Q4DA
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

3-(2-Aminoethyl)phenol hydrochloride

Systematic Name

English

Phenol, 3-(2-aminoethyl)-, hydrochloride

Common Name

English

Phenol, 3-(2-aminoethyl)-, hydrochloride (1:1)

Systematic Name

English

Code System Code Type Description

ECHA (EC/EINECS)

222-396-6