Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C20H24N2O5 |
| Molecular Weight | 372.415 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 1 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=C2O[C@H]3C(CC[C@H]4[C@H]5CC(C=C1)=C2[C@@]34CCN5C)=NOCC(O)=O
InChI
InChIKey=WKJYCUVUZIIMJA-OIBQYEROSA-N
InChI=1S/C20H24N2O5/c1-22-8-7-20-12-4-5-13(21-26-10-16(23)24)19(20)27-18-15(25-2)6-3-11(17(18)20)9-14(12)22/h3,6,12,14,19H,4-5,7-10H2,1-2H3,(H,23,24)/b21-13+/t12-,14+,19-,20-/m0/s1
| Molecular Formula | C20H24N2O5 |
| Molecular Weight | 372.415 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 1 |
| Optical Activity | UNSPECIFIED |
Codoxime is a synthetic derivative of an opiate dihydrocodeinone. It differs from dihydrocodeinone by the substitution of a carboxymethyl oxime for the ketonic oxygen at carbon 6 of the dihydrocodeinone molecule. Codoxime has been proposed as an antitussive with prolonged duration of action. In a clinical trial conducted on prisoner volunteers in 1966, it was found that codoxime has a capacity to produce physical dependence of the morphine type.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Tue Oct 22 19:50:02 UTC 2019
by
admin
on
Tue Oct 22 19:50:02 UTC 2019
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| Record UNII |
JT5I2F57F7
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| Record Status |
Validated (UNII)
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| Record Version |
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230-425-9
Created by
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7125-76-0
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1870
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57358582
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CHEMBL2107300
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SUB06791MIG
Created by
admin on Tue Oct 22 19:50:02 UTC 2019 , Edited by admin on Tue Oct 22 19:50:02 UTC 2019
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| Related Record | Type | Details | ||
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PARENT -> DERIVATIVE |
Dihydrocodeinone-6-carboxymethyloxime (derivate of morphine). as per INCB
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| Related Record | Type | Details | ||
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ACTIVE MOIETY |
