BUTIBUFEN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Possibly Marketed Outside US

Details

Stereochemistry	RACEMIC
Molecular Formula	C14H20O2
Molecular Weight	220.3074
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of BUTIBUFEN

Structure Search

SMILES

CCC(C(O)=O)C1=CC=C(CC(C)C)C=C1

InChI

InChIKey=UULSXYSSHHRCQK-UHFFFAOYSA-N

InChI=1S/C14H20O2/c1-4-13(14(15)16)12-7-5-11(6-8-12)9-10(2)3/h5-8,10,13H,4,9H2,1-3H3,(H,15,16)

HIDE SMILES / InChI

Molecular Formula	C14H20O2
Molecular Weight	220.3074
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/901061 | https://nomenclator.org/medicamento/mijal-500mg-30-sobres.html | https://www.ncbi.nlm.nih.gov/pubmed/9061203

Butibufen is a non-steroidal anti-inflammatory cyclooxygenase inhibitor with analgesic and antipyretic properties. The drug was investigated for the treatment of osteoarthritis, rheumatoid artritis, and other arthroses. It was marketed under tradenames Mijal and Butilopan but now is withdrawn from the market.

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Cyclooxygenase 89 Target ID: CHEMBL2094253 Sources: https://www.ncbi.nlm.nih.gov/pubmed/10579692	Inhibitor 8504

Patents

Patents

Substance Class	Chemical Created by `admin` on `Wed Apr 02 08:45:13 GMT 2025` Edited by `admin` on `Wed Apr 02 08:45:13 GMT 2025`
Record UNII	JSS1TEM917
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

BUTIBUFEN

Official Name

English

BUTIBUFEN [MI]

Preferred Name

English

2-(P-ISOBUTYLPHENYL)BUTYRIC ACID

Common Name

English

butibufen [INN]

Common Name

English

Butibufen [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C257

Created by admin on Wed Apr 02 08:45:13 GMT 2025 , Edited by admin on Wed Apr 02 08:45:13 GMT 2025

Code System Code Type Description

SMS_ID

100000088627

Created by admin on Wed Apr 02 08:45:13 GMT 2025 , Edited by admin on Wed Apr 02 08:45:13 GMT 2025

PRIMARY

EVMPD

SUB06015MIG

Created by admin on Wed Apr 02 08:45:13 GMT 2025 , Edited by admin on Wed Apr 02 08:45:13 GMT 2025

PRIMARY

DRUG CENTRAL

447

Created by admin on Wed Apr 02 08:45:13 GMT 2025 , Edited by admin on Wed Apr 02 08:45:13 GMT 2025

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CAS

55837-18-8

Created by admin on Wed Apr 02 08:45:13 GMT 2025 , Edited by admin on Wed Apr 02 08:45:13 GMT 2025

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MERCK INDEX

m2799

Created by admin on Wed Apr 02 08:45:13 GMT 2025 , Edited by admin on Wed Apr 02 08:45:13 GMT 2025

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Merck Index

FDA UNII

JSS1TEM917

Created by admin on Wed Apr 02 08:45:13 GMT 2025 , Edited by admin on Wed Apr 02 08:45:13 GMT 2025

PRIMARY

EPA CompTox

DTXSID201021603

Created by admin on Wed Apr 02 08:45:13 GMT 2025 , Edited by admin on Wed Apr 02 08:45:13 GMT 2025

PRIMARY

ChEMBL

CHEMBL454450

Created by admin on Wed Apr 02 08:45:13 GMT 2025 , Edited by admin on Wed Apr 02 08:45:13 GMT 2025

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NCI_THESAURUS

C73083

Created by admin on Wed Apr 02 08:45:13 GMT 2025 , Edited by admin on Wed Apr 02 08:45:13 GMT 2025

PRIMARY

RXCUI

19880

Created by admin on Wed Apr 02 08:45:13 GMT 2025 , Edited by admin on Wed Apr 02 08:45:13 GMT 2025

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RxNorm

PUBCHEM

41643

Created by admin on Wed Apr 02 08:45:13 GMT 2025 , Edited by admin on Wed Apr 02 08:45:13 GMT 2025

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MESH

C012797

Created by admin on Wed Apr 02 08:45:13 GMT 2025 , Edited by admin on Wed Apr 02 08:45:13 GMT 2025

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INN

3657

Created by admin on Wed Apr 02 08:45:13 GMT 2025 , Edited by admin on Wed Apr 02 08:45:13 GMT 2025

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ECHA (EC/EINECS)

259-849-2

Created by admin on Wed Apr 02 08:45:13 GMT 2025 , Edited by admin on Wed Apr 02 08:45:13 GMT 2025

PRIMARY

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					JSS1TEM917

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ACTIVE MOIETY