Porustobart

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 15:33:14 GMT 2023` Edited by `admin` on `Sat Dec 16 15:33:14 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY FUSION PROTEIN
Protein Sub Type	HEAVY-CHAIN-ONLY-ANTIBODY\|IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	JJY4JHN685
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Porustobart

Official Name

English

Immunoglobulin G1 [143-aspartic acid,236-glutamic acid], anti-(human cytotoxic T-lymphocyte-associated protein 4) (human monoclonal HBM4003 heavy chain V-D-J region) fusion protein with immunoglobulin G1 (human γ1-chain C region), dimer

Common Name

English

HBM-4003

Code

English

gamma1 VH-h-CH2-CH3 chain Homo sapiens (1-351) [VH(Homo sapiens IGHV3-53*01 (94.8%) -(IGHD) -IGHJ3*02(93.3%), CDR-IMGT [8.7.13] (26-33.51-57.96-108)) (1-119)] -[h-CH2-CH3 (Homo sapiens IGHG1*03 nG1m1, CH3 E12, M14, G1v7 CH2 D3, E117 (hinge 1-15 (120-134)

Common Name

English

HBM4003

Code

English

HBM 4003 [WHO-DD]

Common Name

English

porustobart [INN]

Common Name

English

immunoglobulin gamma1 VH-h-CH2-CH3 dimer, anti-[CTLA4(cytotoxic T-lymphocyte-associated antigen 4, cytotoxic T-lymphocyte-associated protein 4, CTLA-4, CD152)], Homo sapiens heavy-chain only monoclonal antibody, bivalent

Common Name

English

Code System Code Type Description

NCI_THESAURUS

C128036