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Details

Stereochemistry ABSOLUTE
Molecular Formula C4H4O6.2H4N
Molecular Weight 184.1479
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of AMMONIUM TARTRATE

SMILES

[NH4+].[NH4+].O[C@H]([C@@H](O)C([O-])=O)C([O-])=O

InChI

InChIKey=NGPGDYLVALNKEG-OLXYHTOASA-N
InChI=1S/C4H6O6.2H3N/c5-1(3(7)8)2(6)4(9)10;;/h1-2,5-6H,(H,7,8)(H,9,10);2*1H3/t1-,2-;;/m1../s1

HIDE SMILES / InChI

Molecular Formula C4H6O6
Molecular Weight 150.0868
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Molecular Formula H3N
Molecular Weight 17.0305
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Tartaric acid is found in many plants such as grapes, tamarinds, pineapples, mulberries and so on. Wine lees (called mud in the US), the sediment collected during the fermentation of grapes, contains potassium bitartrate (potassium hydrogen tartrate) as its major component. L-(+)-tartaric acid is an enantiomer of tartaric acid. Twenty five years before the tetrahedral structure for carbon was proposed in 1874 to explain the optical activity and other properties of organic compounds, Louis Pasteur discovered the existence of enantiomerism in tartaric acid. L-(+)-tartaric acid is widely used in food and beverage as acidity regulator with E number E334.

Originator

Curator's Comment: Scheele first prepared tartaric acid. Louis Pasteur discovered the existence of enantiomerism in tartaric acid

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Inactive ingredient
CLEARASIL DAILY CLEAR CLEAR SKIN

Approved Use

Unknown
Sourcing

Sourcing

Vendor/AggregatorIDURL
PubMed

PubMed

TitleDatePubMed
Inhibition of leukotriene function can modulate particulate-induced changes in bone cell differentiation and activity.
2001
Effect of brimonidine tartrate ophthalmic solution 0.2% on pupil size in normal eyes under different luminance conditions.
2001 Apr
Vitreous concentration of topically applied brimonidine tartrate 0.2%.
2001 Apr
Synthesis and evaluation of a C-glycosyl nucleoside as an inhibitor of chitin synthase.
2001 Aug 30
Cinchoninium L-tartrate tetrahydrate.
2001 Dec
Production and chemiluminescent free radical reactions of glyoxal in lipid peroxidation of linoleic acid by the ligninolytic enzyme, manganese peroxidase.
2001 Dec
LAS, a novel selective estrogen receptor modulator with chemopreventive and therapeutic activity in the N-nitroso-N-methylurea-induced rat mammary tumor model.
2001 Dec 15
Cell-surface recognition of biotinylated membrane proteins requires very long spacer arms: an example from glucose-transporter probes.
2001 Jan 8
Arsenic induces expression of the multidrug resistance-associated protein 2 (MRP2) gene in primary rat and human hepatocytes.
2001 Jul
Stabilization of minodronic acid in aqueous solution for parenteral formulation.
2001 Jul 3
Catalytic spectrophotometric determination of vanadium in seawaters based on the bromate oxidative coupling reaction of metol and 2,3,4-trihydroxybenzoic acid.
2001 Jun
Dicaffeoyl- or digalloyl pyrrolidine and furan derivatives as HIV integrase inhibitors.
2001 Jun
Crystal structure analysis and chiral recognition study of Delta-[Ru(bpy)2(py)2][(+)-O,O'-dibenzoylD-tartrate].12H2O and Lambda-[Ru(bpy)2(py)2][(-)-O,O'-dibenzoyl-L-tartrate].12H2O.
2001 Mar 12
[Acid phosphatase, ACP (EC 3.1.3.2)].
2001 Nov
Technetium-99m direct radiolabeling of lanreotide: a somatostatin analog.
2001 Nov
The hygroscopic properties of dicarboxylic and multifunctional acids: measurements and UNIFAC predictions.
2001 Nov 15
Platelet-activating factor modulates a secreted phosphatase activity of the trypanosomatid parasite Herpetomonas muscarum muscarum.
2001 Oct
Direct chiral resolution of tartaric acid in food products by ligand exchange capillary electrophoresis using copper(II)-D-quinic acid as a chiral selector.
2001 Oct 12
Direct chiral resolution of malic acid in apple juice by ligand-exchange capillary electrophoresis using copper(II)-L-tartaric acid as a chiral selector.
2001 Sep
Preformulation studies for an ultrashort-acting neuromuscular blocking agent GW280430A. I. Buffer and cosolvent effects on the solution stability.
2002
Acid phosphatases.
2002 Apr
The structure and mechanism of the type II dehydroquinase from Streptomyces coelicolor.
2002 Apr
Initial stages of cell-matrix adhesion can be mediated and modulated by cell-surface hyaluronan.
2002 Apr
Chiral versus racemic building blocks in supramolecular chemistry: tartrate salts of organic diamines.
2002 Apr
Stereoselective synthesis of myo-inositol via ring-closing metathesis: a building block for glycosylphosphatidylinositol (GPI) anchor synthesis.
2002 Apr 18
Thermophysical properties of pharmaceutically compatible buffers at sub-zero temperatures: implications for freeze-drying.
2002 Feb
Retention of anions on silica-based metalloporphyrin stationary phases.
2002 Feb
Ergotamine-induced anorectal strictures: report of five cases.
2002 Feb
Diaquabis[mu-(R,R)-tartrato-kappa4O1,O2:O3,O4]dinickel(II) trihydrate.
2002 Feb
The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter.
2002 Feb
Fibroblasts from the inner granulation tissue of the pseudocapsule in hips at revision arthroplasty induce osteoclast differentiation, as do stromal cells.
2002 Feb
Screening method for inherited disorders of purine and pyrimidine metabolism by capillary electrophoresis with reversed electroosmotic flow.
2002 Feb 15
Selective estrogen receptor modulators as a new therapeutic drug group: concept to reality in a decade.
2002 Jan
Therapy and disease concepts: the history (and future?) of antimony in cancer.
2002 Jan
Some comparative aspects of the pharmacokinetics of tylosin in buffaloes and cattle.
2002 Jan
Anaerobaculum mobile sp. nov., a novel anaerobic, moderately thermophilic, peptide-fermenting bacterium that uses crotonate as an electron acceptor, and emended description of the genus Anaerobaculum.
2002 Jan
Crystal structure analysis of the exocytosis-sensitive phosphoprotein, pp63/parafusin (phosphoglucomutase), from Paramecium reveals significant conformational variability.
2002 Jan 11
Revision of absolute configuration of enantiomeric (methylenecyclopropyl)carbinols obtained from (R)-(-)- and (S)-(+)-epichlorohydrin and methylenetriphenylphosphorane. Implications for reaction mechanism and improved synthesis of antiviral methylenecyclopropane analogues of nucleosides.
2002 Jan 11
From local adsorption stresses to chiral surfaces: (R,R)-tartaric acid on Ni(110).
2002 Jan 23
Effect of antibiotics on in vitro and in vivo avian cartilage degradation.
2002 Jan-Mar
In vitro antibiotic susceptibility of field isolates of Mycoplasma synoviae in Argentina.
2002 Jan-Mar
Gender- and age-related differences in osteoclast formation from circulating precursors.
2002 Mar
Role of the Multidrug Resistance Protein 1 in protection from heavy metal oxyanions: investigations in vitro and in MRP1-deficient mice.
2002 Mar 1
Potassium antimonyl tartrate induces reactive oxygen species-related apoptosis in human myeloid leukemic HL60 cells.
2002 May
Synovial macrophage-osteoclast differentiation in inflammatory arthritis.
2002 Oct
Ectonucleotide diphosphohydrolase activity in Crithidia deanei.
2002 Oct
Formation of methylantimony species by an aerobic prokaryote: Flavobacterium sp.
2002 Oct
Development of high-affinity ligands and photoaffinity labels for the D-fructose transporter GLUT5.
2002 Oct 15
Large scale gene expression analysis of osteoclastogenesis in vitro and elucidation of NFAT2 as a key regulator.
2002 Oct 25
Symmetric and helical growth of polyacetylene fibers over a single copper crystal derived from copper tartrate decomposition.
2002 Sep 5
Patents

Sample Use Guides

L-(+)-tartaric acid as a food additive. Acceptable Daily Intake: 0-30 mg/kg
Route of Administration: Oral
In Vitro Use Guide
After incubation in medium containing 50 mM L(+)-tartaric acid, osteoclasts and chondroclasts were heavily stained with reaction product.
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:08:56 GMT 2023
Edited
by admin
on Fri Dec 15 16:08:56 GMT 2023
Record UNII
JI8UD88354
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AMMONIUM TARTRATE
Systematic Name English
BUTANEDIOIC ACID, 2,3-DIHYDROXY- (2R,3R)-, AMMONIUM SALT (1:2)
Common Name English
AMMONIUM TARTARICUM
HPUS  
Common Name English
DIAMMONIUM L-(+)-TARTRATE
HSDB  
Systematic Name English
DIAMMONIUM L-(+)-TARTRATE [HSDB]
Common Name English
AMMONIUM D-TARTRATE
Systematic Name English
(R)-2,3-DIHYDROXYBUTANEDIOIC ACID DIAMMONIUM SALT
Common Name English
DIAMMONIUM TARTRATE
Systematic Name English
AMMONIUM TARTARICUM [HPUS]
Common Name English
Code System Code Type Description
CHEBI
63075
Created by admin on Fri Dec 15 16:08:56 GMT 2023 , Edited by admin on Fri Dec 15 16:08:56 GMT 2023
PRIMARY
CAS
3164-29-2
Created by admin on Fri Dec 15 16:08:56 GMT 2023 , Edited by admin on Fri Dec 15 16:08:56 GMT 2023
PRIMARY
ECHA (EC/EINECS)
221-618-9
Created by admin on Fri Dec 15 16:08:56 GMT 2023 , Edited by admin on Fri Dec 15 16:08:56 GMT 2023
PRIMARY
FDA UNII
JI8UD88354
Created by admin on Fri Dec 15 16:08:56 GMT 2023 , Edited by admin on Fri Dec 15 16:08:56 GMT 2023
PRIMARY
SMS_ID
100000134080
Created by admin on Fri Dec 15 16:08:56 GMT 2023 , Edited by admin on Fri Dec 15 16:08:56 GMT 2023
PRIMARY
HSDB
2502
Created by admin on Fri Dec 15 16:08:56 GMT 2023 , Edited by admin on Fri Dec 15 16:08:56 GMT 2023
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PUBCHEM
18486
Created by admin on Fri Dec 15 16:08:56 GMT 2023 , Edited by admin on Fri Dec 15 16:08:56 GMT 2023
PRIMARY
EPA CompTox
DTXSID50889463
Created by admin on Fri Dec 15 16:08:56 GMT 2023 , Edited by admin on Fri Dec 15 16:08:56 GMT 2023
PRIMARY
MESH
C029768
Created by admin on Fri Dec 15 16:08:56 GMT 2023 , Edited by admin on Fri Dec 15 16:08:56 GMT 2023
PRIMARY
EVMPD
SUB59543
Created by admin on Fri Dec 15 16:08:56 GMT 2023 , Edited by admin on Fri Dec 15 16:08:56 GMT 2023
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE