4-Hydroxybenzoic Acid

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H6O3
Molecular Weight	138.1207
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)C1=CC=C(O)C=C1

InChI

InChIKey=FJKROLUGYXJWQN-UHFFFAOYSA-N

InChI=1S/C7H6O3/c8-6-3-1-5(2-4-6)7(9)10/h1-4,8H,(H,9,10)

HIDE SMILES / InChI

Molecular Formula	C7H6O3
Molecular Weight	138.1207
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Purification and properties of p-hydroxybenzoate hydroxylases from Rhodococcus strains.	2001 Aug	11566060
Processes controlling the distribution and natural attenuation of dissolved phenolic compounds in a deep sandstone aquifer.	2001 Dec 15	11820472
Oxidation of p-hydroxybenzoic acid by Fenton's reagent.	2001 Feb	11228990
Synthesis, characterization and in vitro degradation of a new family of alternate poly(ester-anhydrides) based on aliphatic and aromatic diacids.	2001 Feb	11197496
Analytical control of a pharmaceutical formulation of sodium picosulfate by capillary zone electrophoresis.	2001 Feb 10	11232853
Analysis of the pobA and pobR genes controlling expression of p-hydroxybenzoate hydroxylase in Azotobacter chroococcum.	2001 Feb 7	11245981
Polyacrylamides as hydrophilic selectors in non-aqueous capillary electrophoresis.	2001 Jan 5	11206796
Synergistic interactions of multiple mutations on catalysis during the hydroxylation reaction of p-hydroxybenzoate hydroxylase: studies of the Lys297Met, Asn300Asp, and Tyr385Phe mutants reconstituted with 8-Cl-flavin.	2001 Jul 31	11467930
Tagetolone and tagetenolone: two phytotoxic polyketides from Alternaria tagetica.	2001 Mar	11312841
Kinetics of the reaction between ozone and phenolic acids present in agro-industrial wastewaters.	2001 Mar	11235874
Pneumocystis carinii f. sp. carinii synthesizes de novo four homologs of ubiquinone.	2001 Mar-Apr	12095106
Separation of a phenol carboxylating organism from a two-member, strict anaerobic co-culture.	2001 May	11400726
Microbial transformations of p-coumaric acid by Bacillus megaterium and Curvularia lunata.	2001 Nov	11720522
Biomimetic transport of simple olive biophenol and analogues through model biological membranes by differential scanning calorimetry.	2001 Nov	11714292
A novel protein elicitor (PaNie) from Pythium aphanidermatum induces multiple defense responses in carrot, Arabidopsis, and tobacco.	2001 Nov	11706166
Molecularly imprinted polymer using-p-hydroxybenzoic acid, p-hydroxyphenylacetic acid and p-hydroxyphenylpropionic acid as templates.	2001 Nov-Dec	11757071
Aromatic amino acid biosynthesis and production of related compounds from p-hydroxyphenylpyruvic acid by rumen bacteria, protozoa and their mixture.	2002	12395184
The trans-anethole degradation pathway in an Arthrobacter sp.	2002 Apr 5	11805095
Comment on "Oxidation of p-hydroxybenzoic acid by Fenton's reagent" by F.J. Rivas, F.J. Belran, J. Frades, and P. Buxeda.	2002 Feb	11848350
Agastinol and agastenol, novel lignans from Agastache rugosa and their evaluation in an apoptosis inhibition assay.	2002 Mar	11908994
Antioxidant activity of phenolic compounds isolated from Mesona procumbens Hemsl.	2002 May 8	11982431
Novel fluorometric assay for hydroxyl radical prevention capacity using fluorescein as the probe.	2002 May 8	11982397
Synthesis of antisense oligonucleotide-peptide conjugate targeting to GLUT-1 in HepG-2 and MCF-7 Cells.	2002 May-Jun	12009942
Evaluation of the health aspects of methyl paraben: a review of the published literature.	2002 Oct	12387298
Biodegradation of aromatic compounds by white rot and ectomycorrhizal fungal species and the accumulation of chlorinated benzoic acid in ectomycorrhizal pine seedlings.	2002 Oct	12363308
Acute toxicity, mutagenicity, and estrogenicity of biodegradation products of bisphenol-A.	2002 Oct	12242676
Antifungal constituents from the seeds of Allium fistulosum L.	2002 Oct 23	12381110
Fast capillary electrochromatographic analysis of parabens and 4-hydroxybenzoic acid in drugs and cosmetics.	2002 Sep	12373771
Physiology of exopolysaccharide production by Azotobacter vinelandii from 4-hydroxybenzoic acid.	2002 Sep	12242634
The relative toxicity of substituted phenols reported in cigarette mainstream smoke.	2002 Sep	12215682
Kinetic, Raman, NMR, and site-directed mutagenesis studies of the Pseudomonas sp. strain CBS3 4-hydroxybenzoyl-CoA thioesterase active site.	2002 Sep 17	12220180

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:36:44 GMT 2025` Edited by `admin` on `Mon Mar 31 19:36:44 GMT 2025`
Record UNII	JG8Z55Y12H
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

4-Hydroxybenzoic Acid

Official Name

English

SALICYLIC ACID RELATED COMPOUND A [USP IMPURITY]

Preferred Name

English

SALICYLIC ACID IMPURITY A [EP IMPURITY]

Common Name

English

ACETYLSALICYLIC ACID IMPURITY A [EP IMPURITY]

Common Name

English

BENZOIC ACID, P-HYDROXY-

Common Name

English

P-HYDROXYBENZOIC ACID [MI]

Common Name

English

PROPYL HYDROXYBENZOATE IMPURITY A [EP IMPURITY]

Common Name

English

4-CARBOXYPHENOL

Systematic Name

English

P-CARBOXYPHENOL

Common Name

English

4-HYDROXYBENZOIC ACID [FHFI]

Common Name

English

PARAHYDROXYBENZOIC ACID

Systematic Name

English

BENZOIC ACID, 4-HYDROXY-

Common Name

English

PARABEN-ACID

Common Name

English

P-SALICYLIC ACID

Common Name

English

P-HYDROXYBENZOIC ACID

Common Name

English

METHYL PARAHYDROXYBENZOATE IMPURITY A [EP IMPURITY]

Common Name

English

SALICYLIC ACID RELATED COMPOUND A [USP-RS]

Common Name

English

NSC-4961

Code

English

FEMA NO. 3986

Code

English

4-HYDROXYBENZOIC ACID [HSDB]

Common Name

English

Classification Tree Code System Code

JECFA EVALUATION

4-HYDROXYBENZOIC ACID