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Details

Stereochemistry ACHIRAL
Molecular Formula C7H6O3
Molecular Weight 138.121
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 4-HYDROXYBENZOIC ACID

SMILES

c1cc(ccc1C(=O)O)O

InChI

InChIKey=FJKROLUGYXJWQN-UHFFFAOYSA-N
InChI=1S/C7H6O3/c8-6-3-1-5(2-4-6)7(9)10/h1-4,8H,(H,9,10)

HIDE SMILES / InChI

Molecular Formula C7H6O3
Molecular Weight 138.121
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Effect of simple phenolic compounds on azoxymethane-induced aberrant crypt foci in rat colon.
2001
Pneumocystis carinii synthesizes four ubiquinone homologs: inhibition by atovaquone and bupravaquone but not by stigmatellin.
2001
Estimation of preservative concentrations in foods and their daily intake based on official inspection results in Japan in fiscal year 1998.
2001 Dec
Phenolic compounds in berries of black, red, green, and white currants (Ribes sp.).
2001 Dec
Processes controlling the distribution and natural attenuation of dissolved phenolic compounds in a deep sandstone aquifer.
2001 Dec 15
Pneumocystis carinii f. sp. carinii synthesizes de novo four homologs of ubiquinone.
2001 Mar-Apr
In vivo hepatoprotective activity of active fraction from ethanolic extract of Eclipta alba leaves.
2001 Oct
Aromatic amino acid biosynthesis and production of related compounds from p-hydroxyphenylpyruvic acid by rumen bacteria, protozoa and their mixture.
2002
Collective vibrational modes in biological molecules investigated by terahertz time-domain spectroscopy.
2002
Antioxidative phenolic compounds isolated from almond skins (Prunus amygdalus Batsch).
2002 Apr 10
Phenolic compounds and antioxidant capacity of Georgia-grown blueberries and blackberries.
2002 Apr 10
The effect of ethanol on the simultaneous transport and metabolism of methyl p-hydroxybenzoate in excised skin of Yucatan micropig.
2002 Apr 2
Co-oxidation of p-hydroxybenzoic acid and atrazine by the Fenton's like system Fe(III)/H2O2.
2002 Apr 26
High level expression of chorismate pyruvate-lyase (UbiC) and HMG-CoA reductase in hairy root cultures of Lithospermum erythrorhizon.
2002 Aug
Assignment of absolute configuration of chiral carboxylic acids via exciton-coupled CD treatment: 4-phenylthioproline as a case study.
2002 Aug
Retention of anions on silica-based metalloporphyrin stationary phases.
2002 Feb
Comment on "Oxidation of p-hydroxybenzoic acid by Fenton's reagent" by F.J. Rivas, F.J. Belran, J. Frades, and P. Buxeda.
2002 Feb
Anaerobic biotransformation of tetrabromobisphenol A, tetrachlorobisphenol A, and bisphenol A in estuarine sediments.
2002 Feb 15
Why phenolic acids are unlikely primary allelochemicals in rice.
2002 Jan
Nonlinear analysis of dynamic binding in affinity capillary electrophoresis demonstrated for inclusion complexes of beta-cyclodextrin.
2002 Jan 11
Chorismate lyase: kinetics and engineering for stability.
2002 Jan 31
Multiple operons connected with catabolism of aromatic compounds in Acinetobacter sp. strain ADP1 are under carbon catabolite repression.
2002 Jul
Effects of butyl paraben on the male reproductive system in mice.
2002 Jul
An in vitro hydroxyl radical generation assay for microdialysis sampling calibration.
2002 Jul 1
Role of protein flexibility in the catalytic cycle of p-hydroxybenzoate hydroxylase elucidated by the Pro293Ser mutant.
2002 Jul 2
Enhanced detection and characterization of protocatechuate 3,4-dioxygenase in Acinetobacter lwoffii K24 by proteomics using a column separation.
2002 Jul 26
X-ray crystallographic analyses of inhibitor and substrate complexes of wild-type and mutant 4-hydroxybenzoyl-CoA thioesterase.
2002 Jul 26
Oestrogenic activity of isobutylparaben in vitro and in vivo.
2002 Jul-Aug
Determination of free and total phenolic acids in plant-derived foods by HPLC with diode-array detection.
2002 Jun 19
Degradation of biphenyl by Mycobacterium sp. strain PYR-1.
2002 Mar
Agastinol and agastenol, novel lignans from Agastache rugosa and their evaluation in an apoptosis inhibition assay.
2002 Mar
Reclassification of Clostridium hydroxybenzoicum as Sedimentibacter hydroxybenzoicus gen. nov., comb. nov., and description of Sedimentibacter saalensis sp. nov..
2002 May
Migration of monomers from liquid crystalline poly(p-hydroxybenzoic acid-co-2-hydroxy-6-naphthoic acid).
2002 May
4-Hydroxycinnamoyl-CoA hydratase/lyase, an enzyme of phenylpropanoid cleavage from Pseudomonas, causes formation of C(6)-C(1) acid and alcohol glucose conjugates when expressed in hairy roots of Datura stramonium L.
2002 May
Isolation from a shea cake digester of a tannin-tolerant Escherichia coli strain decarboxylating p-hydroxybenzoic and vanillic acids.
2002 May
Antioxidant activity of phenolic compounds isolated from Mesona procumbens Hemsl.
2002 May 8
Novel fluorometric assay for hydroxyl radical prevention capacity using fluorescein as the probe.
2002 May 8
On the application of 4-hydroxybenzoic acid as a trapping agent to study hydroxyl radical generation during cerebral ischemia and reperfusion.
2002 May-Jun
[The nature of melanin pigments from some micro- and macromycetes].
2002 May-Jun
Synthesis of antisense oligonucleotide-peptide conjugate targeting to GLUT-1 in HepG-2 and MCF-7 Cells.
2002 May-Jun
Evaluation of the health aspects of methyl paraben: a review of the published literature.
2002 Oct
Biodegradation of aromatic compounds by white rot and ectomycorrhizal fungal species and the accumulation of chlorinated benzoic acid in ectomycorrhizal pine seedlings.
2002 Oct
Acute toxicity, mutagenicity, and estrogenicity of biodegradation products of bisphenol-A.
2002 Oct
Role of the pks15/1 gene in the biosynthesis of phenolglycolipids in the Mycobacterium tuberculosis complex. Evidence that all strains synthesize glycosylated p-hydroxybenzoic methyl esters and that strains devoid of phenolglycolipids harbor a frameshift mutation in the pks15/1 gene.
2002 Oct 11
Antifungal constituents from the seeds of Allium fistulosum L.
2002 Oct 23
Fast capillary electrochromatographic analysis of parabens and 4-hydroxybenzoic acid in drugs and cosmetics.
2002 Sep
Physiology of exopolysaccharide production by Azotobacter vinelandii from 4-hydroxybenzoic acid.
2002 Sep
The relative toxicity of substituted phenols reported in cigarette mainstream smoke.
2002 Sep
Germination inhibitory constituents from Erigeron annuus.
2002 Sep
Kinetic, Raman, NMR, and site-directed mutagenesis studies of the Pseudomonas sp. strain CBS3 4-hydroxybenzoyl-CoA thioesterase active site.
2002 Sep 17
Patents
Substance Class Chemical
Created
by admin
on Sat Jun 26 13:30:16 UTC 2021
Edited
by admin
on Sat Jun 26 13:30:16 UTC 2021
Record UNII
JG8Z55Y12H
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
4-HYDROXYBENZOIC ACID
FHFI   HSDB   INCI  
INCI  
Official Name English
SALICYLIC ACID RELATED COMPOUND A [USP]
USP-RS  
Common Name English
4-HYDROXYBENZOIC ACID [INCI]
Common Name English
BENZOIC ACID, P-HYDROXY-
Common Name English
PROPYL HYDROXYBENZOATE IMPURITY A [EP]
Common Name English
METHYL PARAHYDROXYBENZOATE IMPURITY A [EP]
Common Name English
ACETYLSALICYLIC ACID IMPURITY A [EP]
Common Name English
P-HYDROXYBENZOIC ACID [MI]
Common Name English
SALICYLIC ACID IMPURITY A [EP]
Common Name English
4-CARBOXYPHENOL
Systematic Name English
P-CARBOXYPHENOL
Common Name English
4-HYDROXYBENZOIC ACID [FHFI]
Common Name English
PARAHYDROXYBENZOIC ACID
Systematic Name English
BENZOIC ACID, 4-HYDROXY-
Common Name English
PARABEN-ACID
Common Name English
P-SALICYLIC ACID
Common Name English
P-HYDROXYBENZOIC ACID
MI  
Common Name English
SALICYLIC ACID RELATED COMPOUND A [USP-RS]
Common Name English
NSC-4961
Code English
FEMA NO. 3986
Code English
4-HYDROXYBENZOIC ACID [HSDB]
Common Name English
Classification Tree Code System Code
JECFA EVALUATION 4-HYDROXYBENZOIC ACID
Created by admin on Sat Jun 26 13:30:17 UTC 2021 , Edited by admin on Sat Jun 26 13:30:17 UTC 2021
Code System Code Type Description
RXCUI
1649527
Created by admin on Sat Jun 26 13:30:17 UTC 2021 , Edited by admin on Sat Jun 26 13:30:17 UTC 2021
PRIMARY RxNorm
CAS
99-96-7
Created by admin on Sat Jun 26 13:30:17 UTC 2021 , Edited by admin on Sat Jun 26 13:30:17 UTC 2021
PRIMARY
WIKIPEDIA
4-HYDROXYBENZOIC ACID
Created by admin on Sat Jun 26 13:30:17 UTC 2021 , Edited by admin on Sat Jun 26 13:30:17 UTC 2021
PRIMARY
USP_CATALOG
1609013
Created by admin on Sat Jun 26 13:30:17 UTC 2021 , Edited by admin on Sat Jun 26 13:30:17 UTC 2021
PRIMARY USP-RS
FDA UNII
JG8Z55Y12H
Created by admin on Sat Jun 26 13:30:17 UTC 2021 , Edited by admin on Sat Jun 26 13:30:17 UTC 2021
PRIMARY
HSDB
7233
Created by admin on Sat Jun 26 13:30:17 UTC 2021 , Edited by admin on Sat Jun 26 13:30:17 UTC 2021
PRIMARY
EVMPD
SUB14772MIG
Created by admin on Sat Jun 26 13:30:17 UTC 2021 , Edited by admin on Sat Jun 26 13:30:17 UTC 2021
PRIMARY
DRUG BANK
DB04242
Created by admin on Sat Jun 26 13:30:17 UTC 2021 , Edited by admin on Sat Jun 26 13:30:17 UTC 2021
PRIMARY
MERCK INDEX
M6120
Created by admin on Sat Jun 26 13:30:17 UTC 2021 , Edited by admin on Sat Jun 26 13:30:17 UTC 2021
PRIMARY Merck Index
PUBCHEM
135
Created by admin on Sat Jun 26 13:30:17 UTC 2021 , Edited by admin on Sat Jun 26 13:30:17 UTC 2021
PRIMARY
MESH
C038193
Created by admin on Sat Jun 26 13:30:17 UTC 2021 , Edited by admin on Sat Jun 26 13:30:17 UTC 2021
PRIMARY
ECHA (EC/EINECS)
202-804-9
Created by admin on Sat Jun 26 13:30:17 UTC 2021 , Edited by admin on Sat Jun 26 13:30:17 UTC 2021
PRIMARY
EPA CompTox
99-96-7
Created by admin on Sat Jun 26 13:30:17 UTC 2021 , Edited by admin on Sat Jun 26 13:30:17 UTC 2021
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
SALT/SOLVATE -> PARENT
PARENT -> CONSTITUENT ALWAYS PRESENT
PARENT -> CONSTITUENT ALWAYS PRESENT
PARENT -> CONSTITUENT ALWAYS PRESENT
PARENT -> CONSTITUENT ALWAYS PRESENT
Related Record Type Details
PARENT -> IMPURITY
correction factor: for the calculation of content, multiply the peak area of impurity A by 1.4
CHROMATOGRAPHIC PURITY (HPLC/UV)
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PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
Ph.Eur.; USP