4-HYDROXYBENZOIC ACID

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H6O3
Molecular Weight	138.1207
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)C1=CC=C(O)C=C1

InChI

InChIKey=FJKROLUGYXJWQN-UHFFFAOYSA-N

InChI=1S/C7H6O3/c8-6-3-1-5(2-4-6)7(9)10/h1-4,8H,(H,9,10)

HIDE SMILES / InChI

Molecular Formula	C7H6O3
Molecular Weight	138.1207
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
The influence of type and quantity of model drug on the extrusion/spheronization of mixtures with microcrystalline cellulose. I. Extrusion parameters.	2001 Apr 17	11292559
Protein dynamics control proton transfers to the substrate on the His72Asn mutant of p-hydroxybenzoate hydroxylase.	2001 Apr 3	11300768
Purification and properties of p-hydroxybenzoate hydroxylases from Rhodococcus strains.	2001 Aug	11566060
Phenolic compounds in berries of black, red, green, and white currants (Ribes sp.).	2001 Dec	11813993
Processes controlling the distribution and natural attenuation of dissolved phenolic compounds in a deep sandstone aquifer.	2001 Dec 15	11820472
Non-ionic micellar affinity capillary electrophoresis for analysis of interactions between micelles and drugs.	2001 Feb	11272320
Analytical control of a pharmaceutical formulation of sodium picosulfate by capillary zone electrophoresis.	2001 Feb 10	11232853
Analysis of the pobA and pobR genes controlling expression of p-hydroxybenzoate hydroxylase in Azotobacter chroococcum.	2001 Feb 7	11245981
Quantitative and qualitative precision improvements by effective mobility-scale data transformation in capillary electrophoresis analysis.	2001 Jan	11197183
Polyacrylamides as hydrophilic selectors in non-aqueous capillary electrophoresis.	2001 Jan 5	11206796
A germacranolide and three hydroxybenzyl alcohol derivatives from Hieracium murorum and Crepis bocconi.	2001 Jul-Aug	11705336
Tagetolone and tagetenolone: two phytotoxic polyketides from Alternaria tagetica.	2001 Mar	11312841
[Bergenia crassifolia (L.) Fritsch in vitro].	2001 Mar	11288595
Kinetics of the reaction between ozone and phenolic acids present in agro-industrial wastewaters.	2001 Mar	11235874
Monitoring of Lactobacillus fermentation process by using ion chromatography with a series piezoelectric quartz crystal detector.	2001 Mar 1	11165339
Separation of a phenol carboxylating organism from a two-member, strict anaerobic co-culture.	2001 May	11400726
Microbial transformations of p-coumaric acid by Bacillus megaterium and Curvularia lunata.	2001 Nov	11720522
Kinetic model for phenolic compound oxidation by Fenton's reagent.	2001 Oct	11572595
Ubiquinone biosynthesis in microorganisms.	2001 Sep 25	11583838
Aromatic amino acid biosynthesis and production of related compounds from p-hydroxyphenylpyruvic acid by rumen bacteria, protozoa and their mixture.	2002	12395184
Collective vibrational modes in biological molecules investigated by terahertz time-domain spectroscopy.	2002	12012455
Antioxidative phenolic compounds isolated from almond skins (Prunus amygdalus Batsch).	2002 Apr 10	11929314
Phenolic compounds and antioxidant capacity of Georgia-grown blueberries and blackberries.	2002 Apr 10	11929309
The effect of ethanol on the simultaneous transport and metabolism of methyl p-hydroxybenzoate in excised skin of Yucatan micropig.	2002 Apr 2	11891068
Co-oxidation of p-hydroxybenzoic acid and atrazine by the Fenton's like system Fe(III)/H2O2.	2002 Apr 26	11900911
The trans-anethole degradation pathway in an Arthrobacter sp.	2002 Apr 5	11805095
Anaerobic biotransformation of tetrabromobisphenol A, tetrachlorobisphenol A, and bisphenol A in estuarine sediments.	2002 Feb 15	11878385
Nonlinear analysis of dynamic binding in affinity capillary electrophoresis demonstrated for inclusion complexes of beta-cyclodextrin.	2002 Jan 11	11820274
Nature of impurities in fertilizers containing EDDHMA/Fe(3+), EDDHSA/Fe(3+), and EDDCHA/Fe(3+) chelates.	2002 Jan 16	11782196
Chorismate lyase: kinetics and engineering for stability.	2002 Jan 31	11825618
Multiple operons connected with catabolism of aromatic compounds in Acinetobacter sp. strain ADP1 are under carbon catabolite repression.	2002 Jul	12125820
Effects of butyl paraben on the male reproductive system in mice.	2002 Jul	12111007
Enhanced detection and characterization of protocatechuate 3,4-dioxygenase in Acinetobacter lwoffii K24 by proteomics using a column separation.	2002 Jul 26	12127980
Degradation of biphenyl by Mycobacterium sp. strain PYR-1.	2002 Mar	11935189
Migration of monomers from liquid crystalline poly(p-hydroxybenzoic acid-co-2-hydroxy-6-naphthoic acid).	2002 May	12028649
4-Hydroxycinnamoyl-CoA hydratase/lyase, an enzyme of phenylpropanoid cleavage from Pseudomonas, causes formation of C(6)-C(1) acid and alcohol glucose conjugates when expressed in hairy roots of Datura stramonium L.	2002 May	12012244
Isolation from a shea cake digester of a tannin-tolerant Escherichia coli strain decarboxylating p-hydroxybenzoic and vanillic acids.	2002 May	11927985
Novel fluorometric assay for hydroxyl radical prevention capacity using fluorescein as the probe.	2002 May 8	11982397
Synthesis of antisense oligonucleotide-peptide conjugate targeting to GLUT-1 in HepG-2 and MCF-7 Cells.	2002 May-Jun	12009942
Evaluation of the health aspects of methyl paraben: a review of the published literature.	2002 Oct	12387298
Role of the pks15/1 gene in the biosynthesis of phenolglycolipids in the Mycobacterium tuberculosis complex. Evidence that all strains synthesize glycosylated p-hydroxybenzoic methyl esters and that strains devoid of phenolglycolipids harbor a frameshift mutation in the pks15/1 gene.	2002 Oct 11	12138124
Antifungal constituents from the seeds of Allium fistulosum L.	2002 Oct 23	12381110
Fast capillary electrochromatographic analysis of parabens and 4-hydroxybenzoic acid in drugs and cosmetics.	2002 Sep	12373771
Physiology of exopolysaccharide production by Azotobacter vinelandii from 4-hydroxybenzoic acid.	2002 Sep	12242634
Kinetic, Raman, NMR, and site-directed mutagenesis studies of the Pseudomonas sp. strain CBS3 4-hydroxybenzoyl-CoA thioesterase active site.	2002 Sep 17	12220180

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:12:43 GMT 2023` Edited by `admin` on `Fri Dec 15 19:12:43 GMT 2023`
Record UNII	JG8Z55Y12H
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

4-HYDROXYBENZOIC ACID

Official Name

English

SALICYLIC ACID IMPURITY A [EP IMPURITY]

Common Name

English

ACETYLSALICYLIC ACID IMPURITY A [EP IMPURITY]

Common Name

English

4-HYDROXYBENZOIC ACID [INCI]

Common Name

English

BENZOIC ACID, P-HYDROXY-

Common Name

English

P-HYDROXYBENZOIC ACID [MI]

Common Name

English

PROPYL HYDROXYBENZOATE IMPURITY A [EP IMPURITY]

Common Name

English

4-CARBOXYPHENOL

Systematic Name

English

P-CARBOXYPHENOL

Common Name

English

4-HYDROXYBENZOIC ACID [FHFI]

Common Name

English

PARAHYDROXYBENZOIC ACID

Systematic Name

English

BENZOIC ACID, 4-HYDROXY-

Common Name

English

PARABEN-ACID

Common Name

English

P-SALICYLIC ACID

Common Name

English

P-HYDROXYBENZOIC ACID

Common Name

English

METHYL PARAHYDROXYBENZOATE IMPURITY A [EP IMPURITY]

Common Name

English

SALICYLIC ACID RELATED COMPOUND A [USP-RS]

Common Name

English

NSC-4961

Code

English

FEMA NO. 3986

Code

English

SALICYLIC ACID RELATED COMPOUND A [USP IMPURITY]

Common Name

English

4-HYDROXYBENZOIC ACID [HSDB]

Common Name

English

Classification Tree Code System Code

JECFA EVALUATION

4-HYDROXYBENZOIC ACID