S31-201

CC1=CC=C(C=C1)S(=O)(=O)OCC(=O)NC2=CC=C(C(O)=O)C(O)=C2

InChIKey=HWNUSGNZBAISFM-UHFFFAOYSA-N

InChI=1S/C16H15NO7S/c1-10-2-5-12(6-3-10)25(22,23)24-9-15(19)17-11-4-7-13(16(20)21)14(18)8-11/h2-8,18H,9H2,1H3,(H,17,19)(H,20,21)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
Signal transducer and activator of transcription 3 10 Target ID: P40763 Gene ID: 6774.0 Gene Symbol: STAT3 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/17463090	Inhibitor 8297		86.0 µM [IC50]

PubMed

Title	Date	PubMed
Luteolin enhances paclitaxel-induced apoptosis in human breast cancer MDA-MB-231 cells by blocking STAT3.	2014 Apr 25	24525192
Antitumor progression potential of morusin suppressing STAT3 and NFκB in human hepatoma SK-Hep1 cells.	2015 Jan 22	25476160

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 08:32:55 GMT 2023` Edited by `admin` on `Sat Dec 16 08:32:55 GMT 2023`
Record UNII	JG1E8503OI
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

S31-201

Common Name

English

BENZOIC ACID, 2-HYDROXY-4-((2-(((4-METHYLPHENYL)SULFONYL)OXY)ACETYL)AMINO)-

Common Name

English

S3I-201

Code

English

NSC-74859

Code

English

Code System Code Type Description

FDA UNII

JG1E8503OI