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Details

Stereochemistry ACHIRAL
Molecular Formula C8H9N3O2
Molecular Weight 179.176
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ACETYLISONIAZID

SMILES

CC(=O)NNC(=O)C1=CC=NC=C1

InChI

InChIKey=CVBGNAKQQUWBQV-UHFFFAOYSA-N
InChI=1S/C8H9N3O2/c1-6(12)10-11-8(13)7-2-4-9-5-3-7/h2-5H,1H3,(H,10,12)(H,11,13)

HIDE SMILES / InChI

Molecular Formula C8H9N3O2
Molecular Weight 179.176
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Increased urinary excretion of toxic hydrazino metabolites of isoniazid by slow acetylators. Effect of a slow-release preparation of isoniazid.
1987
Determination of antitubercular drugs in urine and pharmaceuticals by LC using a gradient flow combined with programmed diode array photometric detection.
2002 Aug 23
Determination of the acetylator phenotype in Moroccan tuberculosis patients using isoniazid as metabolic probe.
2002 Dec
A simplified method for detecting isoniazid compliance in patients receiving antituberculosis chemotherapy.
2002 Feb
Unchanged acetylation of isoniazid by alcohol intake.
2004 Nov
The effects of acute ethanol intake on isoniazid pharmacokinetics.
2004 Nov
Microparticle-based lung delivery of INH decreases INH metabolism and targets alveolar macrophages.
2005 Oct 3
The influence of NAT2 genotypes on the plasma concentration of isoniazid and acetylisoniazid in Chinese pulmonary tuberculosis patients.
2006 Mar
Tuberculosis chemotherapy: current drug delivery approaches.
2006 Sep 19
Low serum concentrations of anti-tuberculosis drugs and determinants of their serum levels.
2007 Sep
Effects of N-acetyltransferase 2 (NAT2), CYP2E1 and Glutathione-S-transferase (GST) genotypes on the serum concentrations of isoniazid and metabolites in tuberculosis patients.
2008 May
Substance Class Chemical
Created
by admin
on Fri Dec 15 17:34:06 UTC 2023
Edited
by admin
on Fri Dec 15 17:34:06 UTC 2023
Record UNII
J42942UVUN
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ACETYLISONIAZID
Common Name English
(N)1-ACETYLISONIAZID
Common Name English
Code System Code Type Description
MESH
C510884
Created by admin on Fri Dec 15 17:34:06 UTC 2023 , Edited by admin on Fri Dec 15 17:34:06 UTC 2023
PRIMARY
EPA CompTox
DTXSID1020013
Created by admin on Fri Dec 15 17:34:06 UTC 2023 , Edited by admin on Fri Dec 15 17:34:06 UTC 2023
PRIMARY
PUBCHEM
71602
Created by admin on Fri Dec 15 17:34:06 UTC 2023 , Edited by admin on Fri Dec 15 17:34:06 UTC 2023
PRIMARY
FDA UNII
J42942UVUN
Created by admin on Fri Dec 15 17:34:06 UTC 2023 , Edited by admin on Fri Dec 15 17:34:06 UTC 2023
PRIMARY
CAS
1078-38-2
Created by admin on Fri Dec 15 17:34:06 UTC 2023 , Edited by admin on Fri Dec 15 17:34:06 UTC 2023
PRIMARY
CHEBI
7207
Created by admin on Fri Dec 15 17:34:06 UTC 2023 , Edited by admin on Fri Dec 15 17:34:06 UTC 2023
PRIMARY
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