Details
Stereochemistry | ACHIRAL |
Molecular Formula | C8H9N3O2 |
Molecular Weight | 179.176 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(=O)NNC(=O)C1=CC=NC=C1
InChI
InChIKey=CVBGNAKQQUWBQV-UHFFFAOYSA-N
InChI=1S/C8H9N3O2/c1-6(12)10-11-8(13)7-2-4-9-5-3-7/h2-5H,1H3,(H,10,12)(H,11,13)
Molecular Formula | C8H9N3O2 |
Molecular Weight | 179.176 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Increased urinary excretion of toxic hydrazino metabolites of isoniazid by slow acetylators. Effect of a slow-release preparation of isoniazid. | 1987 |
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Determination of antitubercular drugs in urine and pharmaceuticals by LC using a gradient flow combined with programmed diode array photometric detection. | 2002 Aug 23 |
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Determination of the acetylator phenotype in Moroccan tuberculosis patients using isoniazid as metabolic probe. | 2002 Dec |
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A simplified method for detecting isoniazid compliance in patients receiving antituberculosis chemotherapy. | 2002 Feb |
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Unchanged acetylation of isoniazid by alcohol intake. | 2004 Nov |
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The effects of acute ethanol intake on isoniazid pharmacokinetics. | 2004 Nov |
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Microparticle-based lung delivery of INH decreases INH metabolism and targets alveolar macrophages. | 2005 Oct 3 |
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The influence of NAT2 genotypes on the plasma concentration of isoniazid and acetylisoniazid in Chinese pulmonary tuberculosis patients. | 2006 Mar |
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Tuberculosis chemotherapy: current drug delivery approaches. | 2006 Sep 19 |
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Low serum concentrations of anti-tuberculosis drugs and determinants of their serum levels. | 2007 Sep |
|
Effects of N-acetyltransferase 2 (NAT2), CYP2E1 and Glutathione-S-transferase (GST) genotypes on the serum concentrations of isoniazid and metabolites in tuberculosis patients. | 2008 May |
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 17:34:06 UTC 2023
by
admin
on
Fri Dec 15 17:34:06 UTC 2023
|
Record UNII |
J42942UVUN
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Record Status |
Validated (UNII)
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Record Version |
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C510884
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DTXSID1020013
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71602
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J42942UVUN
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1078-38-2
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7207
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PARENT -> METABOLITE INACTIVE |
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