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Details

Stereochemistry ACHIRAL
Molecular Formula C30H38N4.2C2H4O2
Molecular Weight 574.7534
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of QUINDECAMINE ACETATE ANHYDROUS

SMILES

CC(O)=O.CC(O)=O.CC1=CC(NCCCCCCCCCCNC2=C3C=CC=CC3=NC(C)=C2)=C4C=CC=CC4=N1

InChI

InChIKey=KJLDLEIBEQIBFL-UHFFFAOYSA-N
InChI=1S/C30H38N4.2C2H4O2/c1-23-21-29(25-15-9-11-17-27(25)33-23)31-19-13-7-5-3-4-6-8-14-20-32-30-22-24(2)34-28-18-12-10-16-26(28)30;2*1-2(3)4/h9-12,15-18,21-22H,3-8,13-14,19-20H2,1-2H3,(H,31,33)(H,32,34);2*1H3,(H,3,4)

HIDE SMILES / InChI

Molecular Formula C30H38N4
Molecular Weight 454.6495
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C2H4O2
Molecular Weight 60.052
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Quindecamine (also known as UCL-1407) is quinaldine derivative with antibiotic and fungicidal activity. Treatment of rats and mice with Quindecamine (250 mg/kg/ day) each day for 4 weeks followed by 500 mg/kg/day for 2 more weeks reduced spontaneous motility and body weight but produced no pathological abnormalities of the various organs studied. In vitro, the drug showed very good activity against Staphylococcus aureus, Streptococcus hemolyticus, Candida albicans, Trichophyton mentagrophytes, and T. vaginalis. The drug had very good activity in 180 human subjects with various bacterial and mycotic diseases of the skin and mucosa when applied as a 1% salve.

Originator

Sources: JP40028465

Approval Year

PubMed

PubMed

TitleDatePubMed
Compounds that block both intermediate-conductance (IK(Ca)) and small-conductance (SK(Ca)) calcium-activated potassium channels.
2000-04
Patents

Patents

Substance Class Chemical
Created
by admin
on Mon Mar 31 18:28:58 GMT 2025
Edited
by admin
on Mon Mar 31 18:28:58 GMT 2025
Record UNII
J3Y36BPX1R
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
QUINDECAMINE DIACETATE
Preferred Name English
QUINDECAMINE ACETATE ANHYDROUS
Common Name English
1,10-DECANEDIAMINE, N,N'-BIS(2-METHYL-4-QUINOLINYL)-, DIACETATE
Systematic Name English
Code System Code Type Description
PUBCHEM
64739
Created by admin on Mon Mar 31 18:28:58 GMT 2025 , Edited by admin on Mon Mar 31 18:28:58 GMT 2025
PRIMARY
CAS
19146-62-4
Created by admin on Mon Mar 31 18:28:58 GMT 2025 , Edited by admin on Mon Mar 31 18:28:58 GMT 2025
PRIMARY
EPA CompTox
DTXSID80940778
Created by admin on Mon Mar 31 18:28:58 GMT 2025 , Edited by admin on Mon Mar 31 18:28:58 GMT 2025
PRIMARY
FDA UNII
J3Y36BPX1R
Created by admin on Mon Mar 31 18:28:58 GMT 2025 , Edited by admin on Mon Mar 31 18:28:58 GMT 2025
PRIMARY
Related Record Type Details
SOLVATE->ANHYDROUS
Related Record Type Details
ACTIVE MOIETY