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Details

Stereochemistry ACHIRAL
Molecular Formula C6H5O7.2C5H14NO.H
Molecular Weight 398.4498
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CHOLINE MONOHYDROGEN CITRATE

SMILES

C(C(=O)[O-])C(CC(=O)[O-])(C(=O)O)O.C[N+](C)(C)CCO.C[N+](C)(C)CCO

InChI

InChIKey=KGUWSYXISDXUCK-UHFFFAOYSA-L
InChI=1S/C6H8O7.2C5H14NO/c7-3(8)1-6(13,5(11)12)2-4(9)10;2*1-6(2,3)4-5-7/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);2*7H,4-5H2,1-3H3/q;2*+1/p-2

HIDE SMILES / InChI

Molecular Formula C6H5O7
Molecular Weight 189.1
Charge -3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula H
Molecular Weight 1.0079
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C5H14NO
Molecular Weight 104.171
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

TRICHOLINE CITRATE is indicated for the treatment and management of hepatic disorders and asthma symptoms in adults. It exerts lipotropic action in the hepatic cells. It also can lower the symptoms of asthma and reducing the pro-inflammatory and inflammatory mediators of the leukotriene pathway.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Cypron

Approved Use

Cyproheptadine Tricholine Citrate & Sorbitol Syrup is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms: · Occasional Constipation · Liver Disorders · Asthma Symptoms In Adults · Allergic Reactions · Seasonal Allergies · Mild And Uncomplicated Hives
Primary
Cypron

Approved Use

Cyproheptadine Tricholine Citrate & Sorbitol Syrup is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms: · Occasional Constipation · Liver Disorders · Asthma Symptoms In Adults · Allergic Reactions · Seasonal Allergies · Mild And Uncomplicated Hives
Overview

Overview

CYP3A4CYP2C9CYP2D6hERG



OverviewOther

Other InhibitorOther SubstrateOther Inducer









Drug as perpetrator​

Drug as perpetrator​

TargetModalityActivityMetaboliteClinical evidence
moderate
moderate
moderate
no [Activation >10 uM]
no [Activation >10 uM]
no [Activation >10 uM]
no [Activation >10 uM]
no [Activation >10 uM]
no
yes
Drug as victim
Substance Class Chemical
Created
by admin
on Sat Jun 26 09:44:58 UTC 2021
Edited
by admin
on Sat Jun 26 09:44:58 UTC 2021
Record UNII
J18484727O
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CHOLINE MONOHYDROGEN CITRATE
Systematic Name English
ETHANAMINIUM, 2-HYDROXY-N,N,N-TRIMETHYL-, 2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE (2:1)
Systematic Name English
Code System Code Type Description
CAS
17159-56-7
Created by admin on Sat Jun 26 09:44:58 UTC 2021 , Edited by admin on Sat Jun 26 09:44:58 UTC 2021
PRIMARY
PUBCHEM
72941518
Created by admin on Sat Jun 26 09:44:58 UTC 2021 , Edited by admin on Sat Jun 26 09:44:58 UTC 2021
PRIMARY
FDA UNII
J18484727O
Created by admin on Sat Jun 26 09:44:58 UTC 2021 , Edited by admin on Sat Jun 26 09:44:58 UTC 2021
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
PARENT -> SALT/SOLVATE