Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C22H25NO2 |
| Molecular Weight | 335.4394 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCCN1C=C(C(=O)CC2=C(OC)C=CC=C2)C3=C1C=CC=C3
InChI
InChIKey=FFLSJIQJQKDDCM-UHFFFAOYSA-N
InChI=1S/C22H25NO2/c1-3-4-9-14-23-16-19(18-11-6-7-12-20(18)23)21(24)15-17-10-5-8-13-22(17)25-2/h5-8,10-13,16H,3-4,9,14-15H2,1-2H3
| Molecular Formula | C22H25NO2 |
| Molecular Weight | 335.4394 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
JWH-250 or (1-pentyl-3-(2-methoxyphenylacetyl)indole) is an analgesic chemical from the phenylacetylindole family that acts as a cannabinoid agonist at both the CB1 and CB2 receptors, with a Ki of 11 nM at CB1 and 33 nM at CB2. JWH-250 does not have any therapeutic application, however it is found in many herbal products that are smoked for their psychoactive effects. JWH-250 is a controlled substance by FDA.
CNS Activity
Originator
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Pharmacological characterization of emerging synthetic cannabinoids in HEK293T cells and hippocampal neurons. | 2016-09-05 |
|
| Neurotoxicity of Synthetic Cannabinoids JWH-081 and JWH-210. | 2015-11 |
|
| Development of a high-performance liquid chromatography-tandem mass spectrometry method for the identification and quantification of CP-47,497, CP-47,497-C8 and JWH-250 in mouse brain. | 2014-05-13 |
|
| Development and validation of a liquid chromatography-tandem mass spectrometry method for the identification and quantification of JWH-018, JWH-073, JWH-019, and JWH-250 in human whole blood. | 2011-09 |
|
| 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles. | 2005-09-15 |
Patents
Sample Use Guides
Synthetic cannabioids such as JWH-250 are usually smoked by wrapping it in joints, smoking it in pipes, or inhaling fumes via vaporizers.
Route of Administration:
Respiratory
| Substance Class |
Chemical
Created
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admin
on
Edited
Mon Mar 31 22:09:36 GMT 2025
by
admin
on
Mon Mar 31 22:09:36 GMT 2025
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| Record UNII |
IP9911R8A0
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| Record Status |
Validated (UNII)
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WIKIPEDIA |
Designer-drugs-JWH-250
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DEA NO. |
6250
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DTXSID40235556
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44397540
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JWH-250
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864445-43-2
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ACTIVE MOIETY |
