FLUNIDAZOLE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C11H10FN3O3
Molecular Weight	251.2138
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OCCN1C(=CN=C1C2=CC=C(F)C=C2)[N+]([O-])=O

InChI

InChIKey=OQKHPZHGTCHGOQ-UHFFFAOYSA-N

InChI=1S/C11H10FN3O3/c12-9-3-1-8(2-4-9)11-13-7-10(15(17)18)14(11)5-6-16/h1-4,7,16H,5-6H2

HIDE SMILES / InChI

Molecular Formula	C11H10FN3O3
Molecular Weight	251.2138
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1856129 | https://www.ncbi.nlm.nih.gov/pubmed/2682974 | https://www.ncbi.nlm.nih.gov/pubmed/4077772 | https://www.ncbi.nlm.nih.gov/pubmed/4538856 | https://www.ncbi.nlm.nih.gov/pubmed/4557646

Flunidazole (also known as MK-915) is a 5-nitroimidazole derivative used as an antiparasitic treatment. It has been shown to have both trichomonacidal and amebicidal properties. Flunidazole has been used for the treatment of Trichomonas vaginalis vaginitis, Blastocystis hominis, Entamoeba histolytica and Giardia intestinalis.

Approval Year

PubMed

Title	Date	PubMed
An efficient and selective method for the synthesis of 2-(4-fluorophenyl)-1-(2-hydroxyethyl)-5-nitroimidazole (flunidazole).	1974 May	4830261

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:31:33 GMT 2023` Edited by `admin` on `Sat Dec 16 16:31:33 GMT 2023`
Record UNII	I047971MRN
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FLUNIDAZOLE

Official Name

English

NSC-323560

Code

English

flunidazole [INN]

Common Name

English

FLUNIDAZOLE [USAN]

Common Name

English

1H-IMIDAZOLE-1-ETHANOL, 2-(4-FLUOROPHENYL)-5-NITRO-

Systematic Name

English

2-(P-FLUOROPHENYL)-5-NITROIMIDAZOLE-1-ETHANOL

Common Name

English

Flunidazole [WHO-DD]

Common Name

English

Code System Code Type Description

NSC

323560