PEGADEMASE BOVINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

US Previously Marketed

First approved in 1990

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 18:29:51 GMT 2025` Edited by `admin` on `Mon Mar 31 18:29:51 GMT 2025`
Protein Type	ENZYME
Protein Sub Type	PEGYLATED PROTEIN
Sequence Origin	BOVINE
Sequence Type	COMPLETE
Record UNII	HW3H7D91F6
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

PEG-ADENOSINE DEAMINASE

Preferred Name

English

PEGADEMASE BOVINE

Official Name

English

PEGADEMASE BOVINE [USAN]

Common Name

English

Pegademase

Common Name

English

Adenosine deaminase, cattle, reaction product with succinic anhydride, esters with polyethylene glycol monomethyl ether

Systematic Name

English

PEGADEMASE BOVINE [VANDF]

Common Name

English

Pegademase [WHO-DD]

Common Name

English

PEGADEMASE BOVINE [ORANGE BOOK]

Common Name

English

PEGADEMASE [MART.]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

2084

Created by admin on Mon Mar 31 18:29:51 GMT 2025 , Edited by admin on Mon Mar 31 18:29:51 GMT 2025

NDF-RT

N0000175471

Created by admin on Mon Mar 31 18:29:51 GMT 2025 , Edited by admin on Mon Mar 31 18:29:51 GMT 2025

NCI_THESAURUS

C29726

Created by admin on Mon Mar 31 18:29:51 GMT 2025 , Edited by admin on Mon Mar 31 18:29:51 GMT 2025

WHO-ATC

L03AX04

Created by admin on Mon Mar 31 18:29:51 GMT 2025 , Edited by admin on Mon Mar 31 18:29:51 GMT 2025

NDF-RT

N0000007816

Created by admin on Mon Mar 31 18:29:51 GMT 2025 , Edited by admin on Mon Mar 31 18:29:51 GMT 2025

Code System Code Type Description

NCI_THESAURUS

C77484

Created by admin on Mon Mar 31 18:29:51 GMT 2025 , Edited by admin on Mon Mar 31 18:29:51 GMT 2025

PRIMARY

CAS

130167-68-9

Created by admin on Mon Mar 31 18:29:51 GMT 2025 , Edited by admin on Mon Mar 31 18:29:51 GMT 2025

PRIMARY

FDA UNII

HW3H7D91F6

Created by admin on Mon Mar 31 18:29:51 GMT 2025 , Edited by admin on Mon Mar 31 18:29:51 GMT 2025

PRIMARY

ChEMBL

CHEMBL1201514

Created by admin on Mon Mar 31 18:29:51 GMT 2025 , Edited by admin on Mon Mar 31 18:29:51 GMT 2025

PRIMARY

MESH

C051409

Created by admin on Mon Mar 31 18:29:51 GMT 2025 , Edited by admin on Mon Mar 31 18:29:51 GMT 2025

PRIMARY

DRUG CENTRAL

5206

Created by admin on Mon Mar 31 18:29:51 GMT 2025 , Edited by admin on Mon Mar 31 18:29:51 GMT 2025

PRIMARY

EVMPD

SUB03665MIG

Created by admin on Mon Mar 31 18:29:51 GMT 2025 , Edited by admin on Mon Mar 31 18:29:51 GMT 2025

PRIMARY

SMS_ID

100000115315

Created by admin on Mon Mar 31 18:29:51 GMT 2025 , Edited by admin on Mon Mar 31 18:29:51 GMT 2025

PRIMARY

EVMPD

SUB30488

Created by admin on Mon Mar 31 18:29:51 GMT 2025 , Edited by admin on Mon Mar 31 18:29:51 GMT 2025

PRIMARY

RXCUI

59768

Created by admin on Mon Mar 31 18:29:51 GMT 2025 , Edited by admin on Mon Mar 31 18:29:51 GMT 2025

PRIMARY

RxNorm

LACTMED

Pegademase Bovine

Created by admin on Mon Mar 31 18:29:51 GMT 2025 , Edited by admin on Mon Mar 31 18:29:51 GMT 2025

PRIMARY

USAN

BB-13

Created by admin on Mon Mar 31 18:29:51 GMT 2025 , Edited by admin on Mon Mar 31 18:29:51 GMT 2025

PRIMARY

Related Record Type Details


					XPQ5L1L4WO

ADENOSINE DEAMINASE

TARGET->ENZYME REPLACEMENT

Amount:

Related Record Type Details


					HW3H7D91F6

PEGADEMASE BOVINE

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION			K	Amount:	SUCCINYL MPEG 5000 LYSINE	0W0Q819Z58

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL