BUCRICAINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C17H22N2
Molecular Weight	254.37
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCNC1=C2CCCCC2=NC3=CC=CC=C13

InChI

InChIKey=ZFPNOTAGQWNERF-UHFFFAOYSA-N

InChI=1S/C17H22N2/c1-2-3-12-18-17-13-8-4-6-10-15(13)19-16-11-7-5-9-14(16)17/h4,6,8,10H,2-3,5,7,9,11-12H2,1H3,(H,18,19)

HIDE SMILES / InChI

Molecular Formula	C17H22N2
Molecular Weight	254.37
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/9202137 | https://www.ncbi.nlm.nih.gov/pubmed/4381794

Bucricaine is tetrahydroaminoacridine derivative that has been studied as acetylcholinesterase and monoamine oxidase inhibitor. In animal models, Bucricaine shows a wide spectrum of pharmacological properties, which include analgesic, local anesthetic, analeptic, and respiratory stimulant activities.

Originator

Approval Year

PubMed

Title	Date	PubMed
Studies on a new series of THA analogues: effects of the aromatic residues that line the gorge of AChE.	1997-06-09	9202137

Patents

Substance Class	Chemical Created by `admin` on `Wed Apr 02 09:03:13 GMT 2025` Edited by `admin` on `Wed Apr 02 09:03:13 GMT 2025`
Record UNII	HUC352BGYM
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BUCRICAINE

Official Name

English

9-ACRIDINAMINE, N-BUTYL-1,2,3,4-TETRAHYDRO-

Preferred Name

English

9-(BUTYLAMINO)-1,2,3,4-TETRAHYDROACRIDINE

Systematic Name

English

Bucricaine [WHO-DD]

Common Name

English

ACRIDINE, 9-(BUTYLAMINO)-1,2,3,4-TETRAHYDRO-

Systematic Name

English

bucricaine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C245