Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C22H20F3N5O2 |
| Molecular Weight | 443.4217 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=C(C=NN1C2=NC=CC=C2C(F)(F)F)C(=O)NC3=CC(=CC=C3C)C(=O)NC4CC4
InChI
InChIKey=ZZZJRULMCGMYRH-UHFFFAOYSA-N
InChI=1S/C22H20F3N5O2/c1-12-5-6-14(20(31)28-15-7-8-15)10-18(12)29-21(32)16-11-27-30(13(16)2)19-17(22(23,24)25)4-3-9-26-19/h3-6,9-11,15H,7-8H2,1-2H3,(H,28,31)(H,29,32)
| Molecular Formula | C22H20F3N5O2 |
| Molecular Weight | 443.4217 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Tue Apr 01 16:30:10 GMT 2025
by
admin
on
Tue Apr 01 16:30:10 GMT 2025
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| Record UNII |
HF5XSJ9K57
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| Record Status |
Validated (UNII)
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| Record Version |
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59749702
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796069-97-1
Created by
admin on Tue Apr 01 16:30:10 GMT 2025 , Edited by admin on Tue Apr 01 16:30:10 GMT 2025
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HF5XSJ9K57
Created by
admin on Tue Apr 01 16:30:10 GMT 2025 , Edited by admin on Tue Apr 01 16:30:10 GMT 2025
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| Related Record | Type | Details | ||
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ACTIVE MOIETY |
Originator: Bristol-Myers Squibb; Class: Amide, Thiazole; Mechanism of Action: P38 mitogen-activated protein kinase inhibitor; Highest Development Phase: Preclinical for Inflammation; Most Recent Events: 08 Sep 2010 Preclinical development is ongoing in USA, 20 Aug 2009 Pharmacodynamics and pharmacokinetics data from preclinical trials in Inflammation presented at the 238th American Chemical Society National Meeting (238th-ACS-2009), 23 Aug 2007 Preclinical trials in Inflammation in USA (unspecified route)
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