Details
Stereochemistry | ACHIRAL |
Molecular Formula | C13H6ClN5O2 |
Molecular Weight | 299.672 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
ClC1=CC(=CC2=C1OC3=NC=CC=C3C2=O)C4=NN=NN4
InChI
InChIKey=MLCGWPUVZKTVLO-UHFFFAOYSA-N
InChI=1S/C13H6ClN5O2/c14-9-5-6(12-16-18-19-17-12)4-8-10(20)7-2-1-3-15-13(7)21-11(8)9/h1-5H,(H,16,17,18,19)
Molecular Formula | C13H6ClN5O2 |
Molecular Weight | 299.672 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Traxanox is a diuretic agent possessing an uricosuric effect in animals. The diuretic and uricosuric effects of the drug have also been demonstrated in normotensive healthy subjects. The chronic administration of traxanox reduces serum uric acid level as well as blood pressure in patients with mild to moderate hypertension. This reduction in serum uric acid is due in part to a traxanox-induced elevation of urinary uric acid excretion. Traxanox sodium stimulates the phagocytic activity of leukocytes or macrophages and prevents the drug-induced suppression of the phagocytic activity of these cells. Traxanox may be clinically effective in treating patients with nasal allergies. The mode of action of traxanox on inflammatory responses resembles that of D-penicillamine or levamisole, so that it may prove to be clinically effective in treating rheumatoid arthritis. Also, traxanox may be effective for the treatment of allergic bronchial asthma.
Originator
Approval Year
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:49:58 GMT 2023
by
admin
on
Fri Dec 15 15:49:58 GMT 2023
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Record UNII |
HDU53A8A4S
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Record Status |
Validated (UNII)
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Record Version |
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-
Download
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Official Name | English | ||
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Common Name | English | ||
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Common Name | English |
Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C29712
Created by
admin on Fri Dec 15 15:49:58 GMT 2023 , Edited by admin on Fri Dec 15 15:49:58 GMT 2023
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Code System | Code | Type | Description | ||
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C020178
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3622
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4932
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C66616
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100000077495
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68784
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58712-69-9
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DTXSID50207421
Created by
admin on Fri Dec 15 15:49:58 GMT 2023 , Edited by admin on Fri Dec 15 15:49:58 GMT 2023
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SUB11221MIG
Created by
admin on Fri Dec 15 15:49:58 GMT 2023 , Edited by admin on Fri Dec 15 15:49:58 GMT 2023
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HDU53A8A4S
Created by
admin on Fri Dec 15 15:49:58 GMT 2023 , Edited by admin on Fri Dec 15 15:49:58 GMT 2023
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CHEMBL2009696
Created by
admin on Fri Dec 15 15:49:58 GMT 2023 , Edited by admin on Fri Dec 15 15:49:58 GMT 2023
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m11009
Created by
admin on Fri Dec 15 15:49:58 GMT 2023 , Edited by admin on Fri Dec 15 15:49:58 GMT 2023
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PRIMARY | Merck Index |
Related Record | Type | Details | ||
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ACTIVE MOIETY |