| Stereochemistry | ACHIRAL |
| Molecular Formula | C16H14O4 |
| Molecular Weight | 270.28 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 1 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC(O)=CC(O)=C1C(=O)\C=C\C2=CC=CC=C2
InChI
InChIKey=NYSZJNUIVUBQMM-BQYQJAHWSA-N
InChI=1S/C16H14O4/c1-20-15-10-12(17)9-14(19)16(15)13(18)8-7-11-5-3-2-4-6-11/h2-10,17,19H,1H3/b8-7+
| Molecular Formula | C16H14O4 |
| Molecular Weight | 270.28 |
| Charge | 0 |
| Count |
MOL RATIO
1 MOL RATIO (average) |
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 1 |
| Optical Activity | NONE |
Dihydroxymethoxychalcone (also known as cardamonin) is a chalcone, which is found in many plants, including the cardamom spice. Several studies demonstrated that the drug has anti-inflammatory, antineoplastic, and antioxidant activity. Preclinical experiments have shown that the drug may be a promising agent for the treatment of colorectal cancer, nasopharyngeal carcinoma, and ischemia-reperfusion injury.
Approval Year
PubMed
Patents
Sample Use Guides
In a preclinical study, mice with nasopharyngeal carcinoma were given 5 mg/kg dihydroxymethoxychalcone every day.
Route of Administration:
Intravenous
