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Details

Stereochemistry ACHIRAL
Molecular Formula C19H38O2
Molecular Weight 298.5038
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NONADECANOIC ACID

SMILES

CCCCCCCCCCCCCCCCCCC(O)=O

InChI

InChIKey=ISYWECDDZWTKFF-UHFFFAOYSA-N
InChI=1S/C19H38O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19(20)21/h2-18H2,1H3,(H,20,21)

HIDE SMILES / InChI

Molecular Formula C19H38O2
Molecular Weight 298.5038
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Nonadecanoic acid is an odd-numbered long chain fatty acid, likely derived from bacterial or plant sources. Nonadecanoic acid has been found in ox fats and vegetable oils. It is also used by certain insects as a phermone. Nonadecanoic acid is a saturated fatty acid. It is an antiproliferative agent. Nonadecanoic acid inhibits cancer cell growth (IC50 = 68 uM, HL-60 cells). Energy source in vivo.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
68.0 µM [IC50]
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
TFA and EPA productivities of Nannochloropsis salina influenced by temperature and nitrate stimuli in turbidostatic controlled experiments.
2010-09-27
A conformation and orientation model of the carboxylic group of fatty acids dependent on chain length in a Langmuir monolayer film studied by polarization-modulation infrared reflection absorption spectroscopy.
2010-09-09
Conjugated nonadecadienoic acid is more potent than conjugated linoleic acid on body fat reduction.
2010-08
A simple reversed phase high-performance liquid chromatography method for polysorbate 80 quantitation in monoclonal antibody drug products.
2010-07-01
Understanding organic film behavior on alloy and metal oxides.
2010-02-02
Effect of nitrate supply and mycorrhizal inoculation on characteristics of tobacco root plasma membrane vesicles.
2010-01
Raman microspectroscopy of individual algal cells: sensing unsaturation of storage lipids in vivo.
2010
Identification of light-independent inhibition of human immunodeficiency virus-1 infection through bioguided fractionation of Hypericum perforatum.
2009-07-13
Petiveria alliacea extracts uses multiple mechanisms to inhibit growth of human and mouse tumoral cells.
2008-11-18
[Studies on the constituents from Cacalia ambigua].
2008-11
Possible involvement of long chain fatty acids in the spores of Ganoderma lucidum (Reishi Houshi) to its anti-tumor activity.
2008-10
Evaluation of five methods for derivatization and GC determination of a mixture of very long chain fatty acids (C24:0-C36:0).
2008-01-07
Biodegradation of n-eicosane by fungi screened from nature.
2007-06-01
Self-assembled monolayers of alkanoic acids on the native oxide surface of SS316L by solution deposition.
2007-02-27
Abiotic condensation synthesis of glyceride lipids and wax esters under simulated hydrothermal conditions.
2006-04
Effect of indomethacin on motor activity and spinal cord free fatty acid content after experimental spinal cord injury in rabbits.
2005-09
Validation of a gas chromatographic method for determining fatty acids that compose D003 in 10 mg film-coated tablets.
2004-07
Tunneling characteristics of octadecyl derivatives on tin and indium electrodes.
2004-02-03
Condensation reactions and formation of amides, esters, and nitriles under hydrothermal conditions.
2004
Gas chromatographic method for determining very long chain fatty acids that compose D003 in aqueous suspensions from 20 to 200 mg/ml, used in pharmacological and toxicological studies.
2003-07
GC determination of long chain fatty acids that compose D003 in 5-mg film-coated tablets.
2003-03-26
Alkyl amides and nitriles as novel tracers for biomass burning.
2003-01-01
[Effect of exogenous N-stearoylethanolamine on fatty acid composition of individual phospholipids in the isolated rat heart under postischemic reperfusion].
2002-08-03
Patents

Sample Use Guides

Nonadecanoic acid (C19) reduced the rate of aberrant metaphases from 9.4 to about 3% at doses of 100 mg/kg and less.
Route of Administration: Unknown
Nonadecanoic acid (C19:0) showed the highest inhibitory activity for HL-60 cell proliferation with IC(50) value of 68+/-7 uM.
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:52:04 GMT 2025
Edited
by admin
on Mon Mar 31 18:52:04 GMT 2025
Record UNII
H6M3VYC62P
Record Status Validated (UNII)
Record Version
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Name Type Language
NONADECANOIC ACID
Systematic Name English
NSC-11914
Preferred Name English
N-NONADECANOIC ACID
Common Name English
N-NONADECYLIC ACID
Common Name English
Code System Code Type Description
NSC
11914
Created by admin on Mon Mar 31 18:52:04 GMT 2025 , Edited by admin on Mon Mar 31 18:52:04 GMT 2025
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CAS
646-30-0
Created by admin on Mon Mar 31 18:52:04 GMT 2025 , Edited by admin on Mon Mar 31 18:52:04 GMT 2025
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PUBCHEM
12591
Created by admin on Mon Mar 31 18:52:04 GMT 2025 , Edited by admin on Mon Mar 31 18:52:04 GMT 2025
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CHEBI
39246
Created by admin on Mon Mar 31 18:52:04 GMT 2025 , Edited by admin on Mon Mar 31 18:52:04 GMT 2025
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MESH
C517969
Created by admin on Mon Mar 31 18:52:04 GMT 2025 , Edited by admin on Mon Mar 31 18:52:04 GMT 2025
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WIKIPEDIA
Nonadecanoic acid
Created by admin on Mon Mar 31 18:52:04 GMT 2025 , Edited by admin on Mon Mar 31 18:52:04 GMT 2025
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FDA UNII
H6M3VYC62P
Created by admin on Mon Mar 31 18:52:04 GMT 2025 , Edited by admin on Mon Mar 31 18:52:04 GMT 2025
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EPA CompTox
DTXSID3060954
Created by admin on Mon Mar 31 18:52:04 GMT 2025 , Edited by admin on Mon Mar 31 18:52:04 GMT 2025
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ECHA (EC/EINECS)
211-472-4
Created by admin on Mon Mar 31 18:52:04 GMT 2025 , Edited by admin on Mon Mar 31 18:52:04 GMT 2025
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