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Details

Stereochemistry ACHIRAL
Molecular Formula C19H38O2
Molecular Weight 298.5038
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NONADECANOIC ACID

SMILES

CCCCCCCCCCCCCCCCCCC(O)=O

InChI

InChIKey=ISYWECDDZWTKFF-UHFFFAOYSA-N
InChI=1S/C19H38O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19(20)21/h2-18H2,1H3,(H,20,21)

HIDE SMILES / InChI

Molecular Formula C19H38O2
Molecular Weight 298.5038
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Nonadecanoic acid is an odd-numbered long chain fatty acid, likely derived from bacterial or plant sources. Nonadecanoic acid has been found in ox fats and vegetable oils. It is also used by certain insects as a phermone. Nonadecanoic acid is a saturated fatty acid. It is an antiproliferative agent. Nonadecanoic acid inhibits cancer cell growth (IC50 = 68 uM, HL-60 cells). Energy source in vivo.

Approval Year

Targets

Primary TargetPharmacologyConditionPotency
68.0 µM [IC50]

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

PubMed

Sample Use Guides

In Vivo Use Guide
Nonadecanoic acid (C19) reduced the rate of aberrant metaphases from 9.4 to about 3% at doses of 100 mg/kg and less.
Route of Administration: Unknown
In Vitro Use Guide
Nonadecanoic acid (C19:0) showed the highest inhibitory activity for HL-60 cell proliferation with IC(50) value of 68+/-7 uM.
Substance Class Chemical
Record UNII
H6M3VYC62P
Record Status Validated (UNII)
Record Version