GW-9578

Details

Stereochemistry	ACHIRAL
Molecular Formula	C26H34F2N2O3S
Molecular Weight	492.622
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCCCCN(CCC1=CC=C(SC(C)(C)C(O)=O)C=C1)C(=O)NC2=CC=C(F)C=C2F

InChI

InChIKey=KYQNYMXQHLMADB-UHFFFAOYSA-N

InChI=1S/C26H34F2N2O3S/c1-4-5-6-7-8-16-30(25(33)29-23-14-11-20(27)18-22(23)28)17-15-19-9-12-21(13-10-19)34-26(2,3)24(31)32/h9-14,18H,4-8,15-17H2,1-3H3,(H,29,33)(H,31,32)

HIDE SMILES / InChI

Molecular Formula	C26H34F2N2O3S
Molecular Weight	492.622
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
PPARalpha agonists suppress osteopontin expression in macrophages and decrease plasma levels in patients with type 2 diabetes.	2007-06	17360982
Identification of a subtype selective human PPARalpha agonist through parallel-array synthesis.	2001-05-07	11354382
A ureido-thioisobutyric acid (GW9578) is a subtype-selective PPARalpha agonist with potent lipid-lowering activity.	1999-09-23	10508427
A novel N-aryl tyrosine activator of peroxisome proliferator-activated receptor-gamma reverses the diabetic phenotype of the Zucker diabetic fatty rat.	1999-07	10389847

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:59:50 GMT 2025` Edited by `admin` on `Mon Mar 31 22:59:50 GMT 2025`
Record UNII	H32ABL87X4
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

GW-9578

Common Name

English

PROPANOIC ACID, 2-((4-(2-((((2,4-DIFLUOROPHENYL)AMINO)CARBONYL)HEPTYLAMINO)ETHYL)PHENYL)THIO)-2-METHYL-

Preferred Name

English

Code System Code Type Description

CAS

247923-29-1