DITAZOLE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C19H20N2O3
Molecular Weight	324.3737
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OCCN(CCO)C1=NC(=C(O1)C2=CC=CC=C2)C3=CC=CC=C3

InChI

InChIKey=UUCMDZWCRNZCOY-UHFFFAOYSA-N

InChI=1S/C19H20N2O3/c22-13-11-21(12-14-23)19-20-17(15-7-3-1-4-8-15)18(24-19)16-9-5-2-6-10-16/h1-10,22-23H,11-14H2

HIDE SMILES / InChI

Molecular Formula	C19H20N2O3
Molecular Weight	324.3737
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://botplusweb.portalfarma.com/Documentos/2003/12/5/17853.pdf | https://www.ncbi.nlm.nih.gov/pubmed/6151552

Ditazole, a non-steroidal anti-inflammatory drug with anti-aggregation activity, is marketed under the brand name Ageroplas in Spain and Portugal. Ageroplas is indicated for the prophylaxis and treatment of thrombotic vasculopathy or thromboembolic arteriosclerosis, hypertension, diabetes mellitus, vascular nephropathy, and glomerular, cardiac and vascular prostheses, phlebitis and thrombophlebitis. Ditazole also possesses analgesic and antipyretic activity.

Approval Year

PubMed

Title	Date	PubMed
[Treatment with sulfinpyrazone in comparison with ditazol. Use of dynamic ECG for the study of the cardiac rhythm in patients with recent acute myocardial infarction].	1983 Feb 28	6134600
Effect of a single Ditazole dose on platelet aggregation and prostaglandin formation.	1984	6147319
[Ditazol in the therapy of ischemic cerebrovascular diseases. Clinical results and laboratory experiments (22-to-34-month clinical follow-up)].	1985 Oct 20	2865700

Sample Use Guides

In Vivo Use Guide

phlebitis and thrombophlebitis: one capsule 3 times per day thrombotic diathesis: two weeks of treatment: 2 capsules per day, after main meals, followed by a week off

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:21:20 GMT 2023` Edited by `admin` on `Fri Dec 15 16:21:20 GMT 2023`
Record UNII	H2BQI5Z8FT
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DITAZOLE

Official Name

English

S-222

Code

English

2,2'-((4,5-DIPHENYL-2-OXAZOLYL)IMINO)DIETHANOL

Systematic Name

English

Ditazole [WHO-DD]

Common Name

English

ditazole [INN]

Common Name

English

DITAZOL [MI]

Common Name

English

DITAZOLE [MART.]

Common Name

English

Classification Tree Code System Code

WHO-ATC

B01AC01