U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C19H20N2O3
Molecular Weight 324.3737
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DITAZOLE

SMILES

OCCN(CCO)C1=NC(=C(O1)C2=CC=CC=C2)C3=CC=CC=C3

InChI

InChIKey=UUCMDZWCRNZCOY-UHFFFAOYSA-N
InChI=1S/C19H20N2O3/c22-13-11-21(12-14-23)19-20-17(15-7-3-1-4-8-15)18(24-19)16-9-5-2-6-10-16/h1-10,22-23H,11-14H2

HIDE SMILES / InChI

Molecular Formula C19H20N2O3
Molecular Weight 324.3737
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Ditazole, a non-steroidal anti-inflammatory drug with anti-aggregation activity, is marketed under the brand name Ageroplas in Spain and Portugal. Ageroplas is indicated for the prophylaxis and treatment of thrombotic vasculopathy or thromboembolic arteriosclerosis, hypertension, diabetes mellitus, vascular nephropathy, and glomerular, cardiac and vascular prostheses, phlebitis and thrombophlebitis. Ditazole also possesses analgesic and antipyretic activity.

Approval Year

PubMed

PubMed

TitleDatePubMed
[Ditazol in the therapy of ischemic cerebrovascular diseases. Clinical results and laboratory experiments (22-to-34-month clinical follow-up)].
1985 Oct 20

Sample Use Guides

phlebitis and thrombophlebitis: one capsule 3 times per day thrombotic diathesis: two weeks of treatment: 2 capsules per day, after main meals, followed by a week off
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:21:20 GMT 2023
Edited
by admin
on Fri Dec 15 16:21:20 GMT 2023
Record UNII
H2BQI5Z8FT
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DITAZOLE
INN   MART.   WHO-DD  
INN  
Official Name English
S-222
Code English
2,2'-((4,5-DIPHENYL-2-OXAZOLYL)IMINO)DIETHANOL
Systematic Name English
Ditazole [WHO-DD]
Common Name English
ditazole [INN]
Common Name English
DITAZOL [MI]
Common Name English
DITAZOLE [MART.]
Common Name English
Classification Tree Code System Code
WHO-ATC B01AC01
Created by admin on Fri Dec 15 16:21:20 GMT 2023 , Edited by admin on Fri Dec 15 16:21:20 GMT 2023
WHO-VATC QB01AC01
Created by admin on Fri Dec 15 16:21:20 GMT 2023 , Edited by admin on Fri Dec 15 16:21:20 GMT 2023
NCI_THESAURUS C1327
Created by admin on Fri Dec 15 16:21:20 GMT 2023 , Edited by admin on Fri Dec 15 16:21:20 GMT 2023
Code System Code Type Description
SMS_ID
100000081856
Created by admin on Fri Dec 15 16:21:20 GMT 2023 , Edited by admin on Fri Dec 15 16:21:20 GMT 2023
PRIMARY
WIKIPEDIA
DITAZOLE
Created by admin on Fri Dec 15 16:21:20 GMT 2023 , Edited by admin on Fri Dec 15 16:21:20 GMT 2023
PRIMARY
NCI_THESAURUS
C65442
Created by admin on Fri Dec 15 16:21:20 GMT 2023 , Edited by admin on Fri Dec 15 16:21:20 GMT 2023
PRIMARY
DRUG BANK
DB08994
Created by admin on Fri Dec 15 16:21:20 GMT 2023 , Edited by admin on Fri Dec 15 16:21:20 GMT 2023
PRIMARY
FDA UNII
H2BQI5Z8FT
Created by admin on Fri Dec 15 16:21:20 GMT 2023 , Edited by admin on Fri Dec 15 16:21:20 GMT 2023
PRIMARY
ChEMBL
CHEMBL2104306
Created by admin on Fri Dec 15 16:21:20 GMT 2023 , Edited by admin on Fri Dec 15 16:21:20 GMT 2023
PRIMARY
ECHA (EC/EINECS)
242-353-5
Created by admin on Fri Dec 15 16:21:20 GMT 2023 , Edited by admin on Fri Dec 15 16:21:20 GMT 2023
PRIMARY
EVMPD
SUB06328MIG
Created by admin on Fri Dec 15 16:21:20 GMT 2023 , Edited by admin on Fri Dec 15 16:21:20 GMT 2023
PRIMARY
EPA CompTox
DTXSID3022954
Created by admin on Fri Dec 15 16:21:20 GMT 2023 , Edited by admin on Fri Dec 15 16:21:20 GMT 2023
PRIMARY
PUBCHEM
29088
Created by admin on Fri Dec 15 16:21:20 GMT 2023 , Edited by admin on Fri Dec 15 16:21:20 GMT 2023
PRIMARY
CAS
18471-20-0
Created by admin on Fri Dec 15 16:21:20 GMT 2023 , Edited by admin on Fri Dec 15 16:21:20 GMT 2023
PRIMARY
DRUG CENTRAL
929
Created by admin on Fri Dec 15 16:21:20 GMT 2023 , Edited by admin on Fri Dec 15 16:21:20 GMT 2023
PRIMARY
MERCK INDEX
m4680
Created by admin on Fri Dec 15 16:21:20 GMT 2023 , Edited by admin on Fri Dec 15 16:21:20 GMT 2023
PRIMARY Merck Index
INN
2603
Created by admin on Fri Dec 15 16:21:20 GMT 2023 , Edited by admin on Fri Dec 15 16:21:20 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY