GITALOXIN

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Details

Stereochemistry	ABSOLUTE
Molecular Formula	C42H64O15
Molecular Weight	808.9486
Optical Activity	UNSPECIFIED
Defined Stereocenters	21 / 21
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]1(C[C@H](O)[C@H](O[C@@]2([H])C[C@H](O)[C@H](O[C@@]3([H])C[C@H](O)[C@H](O)[C@@H](C)O3)[C@@H](C)O2)[C@@H](C)O1)O[C@H]4CC[C@@]5(C)[C@]([H])(CC[C@]6([H])[C@]5([H])CC[C@]7(C)[C@H]([C@H](C[C@]67O)OC=O)C8=CC(=O)OC8)C4

InChI

InChIKey=GZZJHPZDXZCDDA-MBJUQXSJSA-N

InChI=1S/C42H64O15/c1-20-37(48)28(44)14-34(52-20)56-39-22(3)54-35(16-30(39)46)57-38-21(2)53-33(15-29(38)45)55-25-8-10-40(4)24(13-25)6-7-27-26(40)9-11-41(5)36(23-12-32(47)50-18-23)31(51-19-43)17-42(27,41)49/h12,19-22,24-31,33-39,44-46,48-49H,6-11,13-18H2,1-5H3/t20-,21-,22-,24-,25+,26+,27-,28+,29+,30+,31+,33+,34+,35+,36+,37-,38-,39-,40+,41-,42+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C42H64O15
Molecular Weight	808.9486
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	21 / 21
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/8986501 | https://www.ncbi.nlm.nih.gov/pubmed/6296702 | https://www.ncbi.nlm.nih.gov/pubmed/14291673

Gitaloxin or 16-formylgiloxine is a cardiotonic glycoside extracted from Digitalis purpurea. It acts as a Na, K-ATPase. Gitaloxin has been investigated in the treatment of cardiac insufficiency.

Approval Year

PubMed

Title	Date	PubMed

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:25:15 GMT 2023` Edited by `admin` on `Sat Dec 16 17:25:15 GMT 2023`
Record UNII	H25D0X8L90
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

GITALOXIN

Official Name

English

GITOXIN 16-FORMATE

Common Name

English

CARD-20(22)-ENOLIDE, 3-((O-2,6-DIDEOXY-.BETA.-D-RIBO-HEXOPYRANOSYL-(1->4)-O-2,6-DIDEOXY-.BETA.-D-RIBO-HEXOPYRANOSYL-(1->4)-2,6-DIDEOXY-.BETA.-D-RIBO-HEXOPYRANOSYL)OXY)-16-(FORMYLOXY)-14-HYDROXY-, (3.BETA.,5.BETA.,16.BETA.)-

Common Name

English

16-FORMYLGITOXIN

Common Name

English

CRISTALOXINE

Common Name

English

Gitaloxin [WHO-DD]

Common Name

English

gitaloxin [INN]

Common Name

English

GITOXIGENIN TRIDIGITOXOSIDE 16-FORMATE

Common Name

English

Code System Code Type Description

INN

4252