.ALPHA.-D-FLUDEOXYGLUCOPYRANOSE

First approved in 1994

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C6H11FO5
Molecular Weight	182.1469
Optical Activity	UNSPECIFIED
Defined Stereocenters	5 / 5
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of .ALPHA.-D-FLUDEOXYGLUCOPYRANOSE

Structure Search

SMILES

OC[C@H]1O[C@H](O)[C@H](F)[C@@H](O)[C@@H]1O

InChI

InChIKey=ZCXUVYAZINUVJD-UKFBFLRUSA-N

InChI=1S/C6H11FO5/c7-3-5(10)4(9)2(1-8)12-6(3)11/h2-6,8-11H,1H2/t2-,3-,4-,5-,6+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C6H11FO5
Molecular Weight	182.1469
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	5 / 5
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: http://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021870s007lbl.pdf

Fludeoxyglucose F-18 is a positron emitting radiopharmaceutical that is used for diagnostic purposes in conjunction with positron emission tomography (PET) imaging.

CNS Activity

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
glucose metabolic process 4 Target ID: GO:0006006 Sources: http://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021870s007lbl.pdf	Interacts 323

Conditions

Condition	Modality	Highest Phase	Product
Cancer 609 Sources: http://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021870s007lbl.pdf	Diagnostic	Approved 8583	FLUDEOXYGLUCOSE F18 Approved Use For positron emission tomography (PET) imaging in oncology, cardiology, neurology. Launch Date 2005
Coronary artery disease 48 Sources: http://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021870s007lbl.pdf	Diagnostic	Approved 8583	FLUDEOXYGLUCOSE F18 Approved Use For positron emission tomography (PET) imaging in oncology, cardiology, neurology. Launch Date 2005
Left ventricular dysfunction 4 Sources: http://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021870s007lbl.pdf	Diagnostic	Approved 8583	FLUDEOXYGLUCOSE F18 Approved Use For positron emission tomography (PET) imaging in oncology, cardiology, neurology. Launch Date 2005
Epileptic seizures 3 Sources: http://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021870s007lbl.pdf	Diagnostic	Approved 8583	FLUDEOXYGLUCOSE F18 Approved Use For positron emission tomography (PET) imaging in oncology, cardiology, neurology. Launch Date 2005

PubMed

Title	Date	PubMed
Future imaging of atherosclerosis: molecular imaging of coronary atherosclerosis with (18)F positron emission tomography.	2016-08	27500093
Impact of (18)FDG PET and (11)C-PIB PET brain imaging on the diagnosis of Alzheimer's disease and other dementias in a regional memory clinic in Hong Kong.	2016-08	27313272
Disseminated histoplasmosis demonstrated on F18-fluorodeoxyglucose positron emission tomography/computed tomography in a renal transplant recipient.	2016-04-21	27095874
Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography imaging in response monitoring of extra-pulmonary tuberculosis.	2016-02-27	26917899
Added value of using a cocktail of F-18 sodium fluoride and F-18 fluorodeoxyglucose in positron emission tomography/computed tomography for detecting bony metastasis: a case report.	2015-04	25837761
The radiation dosimetry of 2 [F-18]fluoro-2-deoxy-D-glucose in man.	1982-07	6979616
Metabolic mapping of functional activity in human subjects with the [18F]fluorodeoxyglucose technique.	1981-05-08	6971492
A shielded synthesis system for production of 2-deoxy-2-[18F]fluoro-D-glucose.	1981-04	7205386
A fluorinated glucose analog, 2-fluoro-2-deoxy-D-glucose (F-18): nontoxic tracer for rapid tumor detection.	1980-07	7391842

Sample Use Guides

In Vivo Use Guide

5 – 10 mCi (adults), 2.6 mCi (pediatric patients)

Route of Administration: Intravenous

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Tue Apr 01 22:12:12 GMT 2025` Edited by `admin` on `Tue Apr 01 22:12:12 GMT 2025`
Record UNII	H0QPM375HE
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

.ALPHA.-D-GLUCOPYRANOSE, 2-DEOXY-2-FLUORO-

Preferred Name

English

.ALPHA.-D-FLUDEOXYGLUCOPYRANOSE

Common Name

English

Code System Code Type Description

CAS

62182-10-9