Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C14H11Cl2NO3 |
| Molecular Weight | 312.148 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OCC1=C(Cl)C(NC2=CC=CC=C2C(O)=O)=C(Cl)C=C1
InChI
InChIKey=SMILHFIJFWZZIM-UHFFFAOYSA-N
InChI=1S/C14H11Cl2NO3/c15-10-6-5-8(7-18)12(16)13(10)17-11-4-2-1-3-9(11)14(19)20/h1-6,17-18H,7H2,(H,19,20)
| Molecular Formula | C14H11Cl2NO3 |
| Molecular Weight | 312.148 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Tue Apr 01 20:35:36 GMT 2025
by
admin
on
Tue Apr 01 20:35:36 GMT 2025
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| Record UNII |
GTG42NLU2Z
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| Record Status |
Validated (UNII)
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| Record Version |
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GTG42NLU2Z
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29981757
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DTXSID10652610
Created by
admin on Tue Apr 01 20:35:36 GMT 2025 , Edited by admin on Tue Apr 01 20:35:36 GMT 2025
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67318-61-0
Created by
admin on Tue Apr 01 20:35:36 GMT 2025 , Edited by admin on Tue Apr 01 20:35:36 GMT 2025
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| Related Record | Type | Details | ||
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TARGET -> INHIBITOR |
Metabolite I, formed by hydroxylation of the methyl group, and its glucuronide conjugates accounted for 50 to 60 per cent of radioactivity in urine (approximately 35 per cent of dose). This metabolite possesses pharmacologic activity equal to one-fifth that of meclofenamic acid in an in vim system which measures inhibition of bovine seminal vesicle cyclo~xygenase.
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| Related Record | Type | Details | ||
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PARENT -> METABOLITE ACTIVE |
Urinary excretion accounts for up to 50-60% of this metabolites. (Active)
MAJOR
URINE
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