Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C14H11Cl2NO3 |
| Molecular Weight | 312.148 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OCC1=CC=C(Cl)C(NC2=C(C=CC=C2)C(O)=O)=C1Cl
InChI
InChIKey=SMILHFIJFWZZIM-UHFFFAOYSA-N
InChI=1S/C14H11Cl2NO3/c15-10-6-5-8(7-18)12(16)13(10)17-11-4-2-1-3-9(11)14(19)20/h1-6,17-18H,7H2,(H,19,20)
| Molecular Formula | C14H11Cl2NO3 |
| Molecular Weight | 312.148 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 13:22:01 UTC 2023
by
admin
on
Sat Dec 16 13:22:01 UTC 2023
|
| Record UNII |
GTG42NLU2Z
|
| Record Status |
Validated (UNII)
|
| Record Version |
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-
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GTG42NLU2Z
Created by
admin on Sat Dec 16 13:22:01 UTC 2023 , Edited by admin on Sat Dec 16 13:22:01 UTC 2023
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29981757
Created by
admin on Sat Dec 16 13:22:01 UTC 2023 , Edited by admin on Sat Dec 16 13:22:01 UTC 2023
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DTXSID10652610
Created by
admin on Sat Dec 16 13:22:01 UTC 2023 , Edited by admin on Sat Dec 16 13:22:01 UTC 2023
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67318-61-0
Created by
admin on Sat Dec 16 13:22:01 UTC 2023 , Edited by admin on Sat Dec 16 13:22:01 UTC 2023
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PRIMARY |
| Related Record | Type | Details | ||
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TARGET -> INHIBITOR |
Metabolite I, formed by hydroxylation of the methyl group, and its glucuronide conjugates accounted for 50 to 60 per cent of radioactivity in urine (approximately 35 per cent of dose). This metabolite possesses pharmacologic activity equal to one-fifth that of meclofenamic acid in an in vim system which measures inhibition of bovine seminal vesicle cyclo~xygenase.
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| Related Record | Type | Details | ||
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PARENT -> METABOLITE ACTIVE |
Urinary excretion accounts for up to 50-60% of this metabolites. (Active)
MAJOR
URINE
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