Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C13H17NO2 |
| Molecular Weight | 219.2796 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)[C@@H]([C@H]1CCCCN1)C2=CC=CC=C2
InChI
InChIKey=INGSNVSERUZOAK-VXGBXAGGSA-N
InChI=1S/C13H17NO2/c15-13(16)12(10-6-2-1-3-7-10)11-8-4-5-9-14-11/h1-3,6-7,11-12,14H,4-5,8-9H2,(H,15,16)/t11-,12-/m1/s1
| Molecular Formula | C13H17NO2 |
| Molecular Weight | 219.2796 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Ritalinic acid is an inactive, major metabolite of methylphenidate, a schedule II drug in the United States commonly used as a psychostimulant drugs methylphenidate and ethylphenidate. The elimination half-life of methylphenidate is relatively short (approximately 2 hours); therefore it is also available in extended release (ER) forms. The main metabolite is ritalinic acid, and the methylphenidate metabolites are mostly excreted in urine.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Biotransformation of ritalinic acid by laccase in the presence of mediator TEMPO. | 2018-07-25 |
|
| Metabolomics of Methylphenidate and Ethylphenidate: Implications in Pharmacological and Toxicological Effects. | 2017-02 |
|
| Identification of selected therapeutic agents as inhibitors of carboxylesterase 1: potential sources of metabolic drug interactions. | 2010-04-11 |
|
| A single-dose, two-way crossover, bioequivalence study of dexmethylphenidate HCl with and without food in healthy subjects. | 2004-02 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:09:16 GMT 2025
by
admin
on
Mon Mar 31 18:09:16 GMT 2025
|
| Record UNII |
GT4165RS9H
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Preferred Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
243-020-7
Created by
admin on Mon Mar 31 18:09:16 GMT 2025 , Edited by admin on Mon Mar 31 18:09:16 GMT 2025
|
PRIMARY | |||
|
19395-41-6
Created by
admin on Mon Mar 31 18:09:16 GMT 2025 , Edited by admin on Mon Mar 31 18:09:16 GMT 2025
|
NON-SPECIFIC STEREOCHEMISTRY | |||
|
54631-24-2
Created by
admin on Mon Mar 31 18:09:16 GMT 2025 , Edited by admin on Mon Mar 31 18:09:16 GMT 2025
|
PRIMARY | |||
|
SUB122938
Created by
admin on Mon Mar 31 18:09:16 GMT 2025 , Edited by admin on Mon Mar 31 18:09:16 GMT 2025
|
PRIMARY | |||
|
DTXSID20864888
Created by
admin on Mon Mar 31 18:09:16 GMT 2025 , Edited by admin on Mon Mar 31 18:09:16 GMT 2025
|
PRIMARY | |||
|
Ritalinic acid
Created by
admin on Mon Mar 31 18:09:16 GMT 2025 , Edited by admin on Mon Mar 31 18:09:16 GMT 2025
|
PRIMARY | |||
|
GT4165RS9H
Created by
admin on Mon Mar 31 18:09:16 GMT 2025 , Edited by admin on Mon Mar 31 18:09:16 GMT 2025
|
PRIMARY | |||
|
100000145107
Created by
admin on Mon Mar 31 18:09:16 GMT 2025 , Edited by admin on Mon Mar 31 18:09:16 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
SALT/SOLVATE -> PARENT |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
PARENT -> METABOLITE INACTIVE |
MAJOR
|
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
PARENT -> IMPURITY |
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
|
||
|
PARENT -> IMPURITY |
Limit is 0.5 at Detector: UV 209 nm
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
|
