Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C13H17NO2.ClH |
| Molecular Weight | 255.741 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.[H][C@@]1(CCCCN1)[C@H](C(O)=O)C2=CC=CC=C2
InChI
InChIKey=SCUMDQFFZZGUQY-MNMPKAIFSA-N
InChI=1S/C13H17NO2.ClH/c15-13(16)12(10-6-2-1-3-7-10)11-8-4-5-9-14-11;/h1-3,6-7,11-12,14H,4-5,8-9H2,(H,15,16);1H/t11-,12-;/m1./s1
| Molecular Formula | C13H17NO2 |
| Molecular Weight | 219.2796 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Ritalinic acid is an inactive, major metabolite of methylphenidate, a schedule II drug in the United States commonly used as a psychostimulant drugs methylphenidate and ethylphenidate. The elimination half-life of methylphenidate is relatively short (approximately 2 hours); therefore it is also available in extended release (ER) forms. The main metabolite is ritalinic acid, and the methylphenidate metabolites are mostly excreted in urine.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| A single-dose, two-way crossover, bioequivalence study of dexmethylphenidate HCl with and without food in healthy subjects. | 2004 Feb |
|
| Identification of selected therapeutic agents as inhibitors of carboxylesterase 1: potential sources of metabolic drug interactions. | 2010 Apr 11 |
|
| Metabolomics of Methylphenidate and Ethylphenidate: Implications in Pharmacological and Toxicological Effects. | 2017 Feb |
|
| Biotransformation of ritalinic acid by laccase in the presence of mediator TEMPO. | 2018 Jul 25 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 09:14:48 GMT 2023
by
admin
on
Sat Dec 16 09:14:48 GMT 2023
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| Record UNII |
2IEY1KK135
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| Record Status |
Validated (UNII)
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19395-40-5
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1382859-13-3
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2IEY1KK135
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49801997
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1434022
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| Related Record | Type | Details | ||
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PARENT -> SALT/SOLVATE |
