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Details

Stereochemistry RACEMIC
Molecular Formula C12H16N2
Molecular Weight 188.2688
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ETRYPTAMINE

SMILES

CCC(N)CC1=CNC2=CC=CC=C12

InChI

InChIKey=ZXUMUPVQYAFTLF-UHFFFAOYSA-N
InChI=1S/C12H16N2/c1-2-10(13)7-9-8-14-12-6-4-3-5-11(9)12/h3-6,8,10,14H,2,7,13H2,1H3

HIDE SMILES / InChI

Molecular Formula C12H16N2
Molecular Weight 188.2688
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

ETRYPTAMINE (MONASE®), similar to the hallucinogenic tryptamines, is an inhibitor of monoamine oxidase, introduced for use as an antidepressant. It was withdrawn from the market due to problems with agranulocytosis and other side effects. However, it's activity is still under scientific investigation.

CNS Activity

Originator

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Monase

T1/2

ValueDoseCo-administeredAnalytePopulation
8.2 h
single, oral
ETRYPTAMINE plasma
Homo sapiens

Doses

AEs

PubMed

Patents

Substance Class Chemical
Record UNII
GR181O3R32
Record Status Validated (UNII)
Record Version