OMOCONAZOLE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H17Cl3N2O2
Molecular Weight	423.72
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C\C(N1C=CN=C1)=C(\OCCOC2=CC=C(Cl)C=C2)C3=C(Cl)C=C(Cl)C=C3

InChI

InChIKey=JMFOSJNGKJCTMJ-ZHZULCJRSA-N

InChI=1S/C20H17Cl3N2O2/c1-14(25-9-8-24-13-25)20(18-7-4-16(22)12-19(18)23)27-11-10-26-17-5-2-15(21)3-6-17/h2-9,12-13H,10-11H2,1H3/b20-14-

HIDE SMILES / InChI

Molecular Formula	C20H17Cl3N2O2
Molecular Weight	423.72
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description
Sources: http://www.onmeda.fr/medicament/fongamil-93327055.html

Omoconazole is an azole antifungal drug, is used to treat candidiasis; dermatophytes and Pityriasis Versicolor

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
Candida infections 20 Sources: http://www.onmeda.fr/medicament/fongamil-93327055.html	Curative	Approved 8429	Unknown Approved Use Unknown
Dermatomycosis 20 Sources: http://www.onmeda.fr/medicament/fongamil-93327055.html	Curative	Approved 8429	Unknown Approved Use Unknown
Pityriasis versicolor 4 Sources: http://www.onmeda.fr/medicament/fongamil-93327055.html	Curative	Approved 8429	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
Ultrastructural alterations of Candida albicans induced by a new imidazole antimycotic omoconazole nitrate.	1997	9194038

Patents

Sample Use Guides

In Vivo Use Guide

Cream; Topical; Omoconazole Nitrate 1%

Route of Administration: Topical

In Vitro Use Guide

The treatment of growing Candida cultures with fungistatic doses (0.4 to 4 micrograms/ml) of omoconazole nitrate (OMZ) produced the formation of a chain or cluster of cells. Thickening of the cell wall and accumulation of electrondense vesicles in the wall were clearly observed

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:47:44 GMT 2023` Edited by `admin` on `Fri Dec 15 15:47:44 GMT 2023`
Record UNII	GQ8ADD54E1
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

OMOCONAZOLE

Official Name

English

Omoconazole [WHO-DD]

Common Name

English

(Z)-1-(2,4-DICHLORO-.BETA.-(2-(P-CHLOROPHENOXY)ETHOXY)-.ALPHA.-METHYLSTYRYL)IMIDAZOLE

Common Name

English

omoconazole [INN]

Common Name

English

OMOCONAZOLE [MI]

Common Name

English

1H-IMIDAZOLE, 1-(2-(2-(4-CHLOROPHENOXY)ETHOXY)-2-(2,4-DICHLOROPHENYL)-1-METHYLETHENYL)-, (Z)-

Common Name

English

Classification Tree Code System Code

WHO-ATC

G01AF16