U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Sat Dec 16 18:54:39 GMT 2023
Edited
by admin
on Sat Dec 16 18:54:39 GMT 2023
Source Materials Class ORGANISM
Source Materials Type AUTOLOGOUS HUMAN
Source Materials State LIVE GENETICALLY MODIFIED
Source Materials Parent
Part BLOOD
Fraction Name T CELLS
Record UNII
GMV2GFP3G2
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ZEVORCABTAGENE AUTOLEUCEL
INN   USAN  
Official Name English
ZEVORCABTAGENE AUTOLEUCEL [USAN]
Common Name English
CT053
Code English
PREPARATION OF AUTOLOGOUS T-LYMPHOCYTES THAT HAVE BEEN TRANSDUCED WITH A VECTOR EXPRESSING A CHIMERIC ANTIGEN RECEPTOR (CAR) CONTAINING A HUMANIZED SINGLE CHAIN VARIABLE FRAGMENT (SCFV) SPECIFIC FOR THE TUMOR-ASSOCIATED ANTIGEN (TAA) B-CELL MATURATION AN
Common Name English
CT-053
Code English
AUTOLOGOUS ANTI-BCMA-CAR-4-1BB-CD3ZETA-EXPRESSING T-CELLS CT053
Common Name English
zevorcabtagene autoleucel [INN]
Common Name English
Code System Code Type Description
USAN
HI-221
Created by admin on Sat Dec 16 18:54:39 GMT 2023 , Edited by admin on Sat Dec 16 18:54:39 GMT 2023
PRIMARY
FDA UNII
GMV2GFP3G2
Created by admin on Sat Dec 16 18:54:39 GMT 2023 , Edited by admin on Sat Dec 16 18:54:39 GMT 2023
PRIMARY
NCI_THESAURUS
C165507
Created by admin on Sat Dec 16 18:54:39 GMT 2023 , Edited by admin on Sat Dec 16 18:54:39 GMT 2023
PRIMARY
INN
11704
Created by admin on Sat Dec 16 18:54:39 GMT 2023 , Edited by admin on Sat Dec 16 18:54:39 GMT 2023
PRIMARY
Related Record Type Details
TARGET->CYTOTOXIC T-CELL
Related Record Type Details
ACTIVE MOIETY

Agent Modifications

Modification Process Modification Role Modification Type Amount Fragment Name Fragment ID
LENTIVIRAL TRANSFECTION UNSPECIFIED SUBSTANCE 658cbe36

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
GENE_EXPRESSION VECTOR UNSPECIFIED SUBSTANCE
8765fcfe
(not in database)