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This repository is under review for potential modification in compliance with Administration directives.

Approval Year

Unknown
149124
Substance Class Structurally Diverse
Created
by admin
on Wed Apr 02 12:46:15 GMT 2025
Edited
by admin
on Wed Apr 02 12:46:15 GMT 2025
Source Materials Class ORGANISM
Source Materials Type AUTOLOGOUS HUMAN
Source Materials State LIVE GENETICALLY MODIFIED
Source Materials Parent
HOMO SAPIENS WHOLE
Part blood
Fraction Name t cells
Record UNII
GMV2GFP3G2
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CT-053
Preferred Name English
ZEVORCABTAGENE AUTOLEUCEL
INN   USAN  
Official Name English
ZEVORCABTAGENE AUTOLEUCEL [USAN]
Common Name English
Zevorcabtagene autoleucel [WHO-DD]
Common Name English
CT053
Code English
PREPARATION OF AUTOLOGOUS T-LYMPHOCYTES THAT HAVE BEEN TRANSDUCED WITH A VECTOR EXPRESSING A CHIMERIC ANTIGEN RECEPTOR (CAR) CONTAINING A HUMANIZED SINGLE CHAIN VARIABLE FRAGMENT (SCFV) SPECIFIC FOR THE TUMOR-ASSOCIATED ANTIGEN (TAA) B-CELL MATURATION AN
Common Name English
AUTOLOGOUS ANTI-BCMA-CAR-4-1BB-CD3ZETA-EXPRESSING T-CELLS CT053
Common Name English
zevorcabtagene autoleucel [INN]
Common Name English
Code System Code Type Description
SMS_ID
300000004761
Created by admin on Wed Apr 02 12:46:15 GMT 2025 , Edited by admin on Wed Apr 02 12:46:15 GMT 2025
PRIMARY
USAN
HI-221
Created by admin on Wed Apr 02 12:46:15 GMT 2025 , Edited by admin on Wed Apr 02 12:46:15 GMT 2025
PRIMARY
FDA UNII
GMV2GFP3G2
Created by admin on Wed Apr 02 12:46:15 GMT 2025 , Edited by admin on Wed Apr 02 12:46:15 GMT 2025
PRIMARY
NCI_THESAURUS
C165507
Created by admin on Wed Apr 02 12:46:15 GMT 2025 , Edited by admin on Wed Apr 02 12:46:15 GMT 2025
PRIMARY
INN
11704
Created by admin on Wed Apr 02 12:46:15 GMT 2025 , Edited by admin on Wed Apr 02 12:46:15 GMT 2025
PRIMARY
Related Record Type Details
TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 17
TARGET->CYTOTOXIC T-CELL
Related Record Type Details
ZEVORCABTAGENE AUTOLEUCEL
ACTIVE MOIETY

Agent Modifications

Modification Process Modification Role Modification Type Amount Fragment Name Fragment ID
LENTIVIRAL TRANSFECTION UNSPECIFIED SUBSTANCE 658cbe36

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
GENE_EXPRESSION VECTOR UNSPECIFIED SUBSTANCE
8765fcfe
(not in database)
NIH
NCATS
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