ZEVORCABTAGENE AUTOLEUCEL

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Sat Dec 16 18:54:39 GMT 2023` Edited by `admin` on `Sat Dec 16 18:54:39 GMT 2023`
Source Materials Class	ORGANISM
Source Materials Type	AUTOLOGOUS HUMAN
Source Materials State	LIVE GENETICALLY MODIFIED
Source Materials Parent	`G0T704E6Z3` HOMO SAPIENS WHOLE
Part	BLOOD
Fraction Name	T CELLS
Record UNII	GMV2GFP3G2
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ZEVORCABTAGENE AUTOLEUCEL

Official Name

English

ZEVORCABTAGENE AUTOLEUCEL [USAN]

Common Name

English

CT053

Code

English

PREPARATION OF AUTOLOGOUS T-LYMPHOCYTES THAT HAVE BEEN TRANSDUCED WITH A VECTOR EXPRESSING A CHIMERIC ANTIGEN RECEPTOR (CAR) CONTAINING A HUMANIZED SINGLE CHAIN VARIABLE FRAGMENT (SCFV) SPECIFIC FOR THE TUMOR-ASSOCIATED ANTIGEN (TAA) B-CELL MATURATION AN

Common Name

English

CT-053

Code

English

AUTOLOGOUS ANTI-BCMA-CAR-4-1BB-CD3ZETA-EXPRESSING T-CELLS CT053

Common Name

English

zevorcabtagene autoleucel [INN]

Common Name

English

Code System Code Type Description

USAN

HI-221

Created by admin on Sat Dec 16 18:54:39 GMT 2023 , Edited by admin on Sat Dec 16 18:54:39 GMT 2023

PRIMARY

FDA UNII

GMV2GFP3G2

Created by admin on Sat Dec 16 18:54:39 GMT 2023 , Edited by admin on Sat Dec 16 18:54:39 GMT 2023

PRIMARY

NCI_THESAURUS

C165507

Created by admin on Sat Dec 16 18:54:39 GMT 2023 , Edited by admin on Sat Dec 16 18:54:39 GMT 2023

PRIMARY

INN

11704

Created by admin on Sat Dec 16 18:54:39 GMT 2023 , Edited by admin on Sat Dec 16 18:54:39 GMT 2023

PRIMARY

Related Record Type Details


					PK6VHJAIBD

TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 17

TARGET->CYTOTOXIC T-CELL

Amount:

Related Record Type Details


					GMV2GFP3G2

ZEVORCABTAGENE AUTOLEUCEL

ACTIVE MOIETY

Amount:

Agent Modifications

Modification Process	Modification Role	Modification Type	Amount	Fragment Name	Fragment ID
LENTIVIRAL TRANSFECTION				UNSPECIFIED SUBSTANCE	658cbe36

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
GENE_EXPRESSION VECTOR					UNSPECIFIED SUBSTANCE	8765fcfe (not in database)