NICOFURANOSE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C30H24N4O10
Molecular Weight	600.5324
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of NICOFURANOSE

Structure Search

SMILES

O[C@]2(COC(=O)C1=CC=CN=C1)O[C@H](COC(=O)C3=CN=CC=C3)[C@@H](OC(=O)C4=CC=CN=C4)[C@@H]2OC(=O)C5=CC=CN=C5

InChI

InChIKey=FUWFSXZKBMCSKF-ZASNTINBSA-N

InChI=1S/C30H24N4O10/c35-26(19-5-1-9-31-13-19)40-17-23-24(42-28(37)21-7-3-11-33-15-21)25(43-29(38)22-8-4-12-34-16-22)30(39,44-23)18-41-27(36)20-6-2-10-32-14-20/h1-16,23-25,39H,17-18H2/t23-,24-,25+,30-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C30H24N4O10
Molecular Weight	600.5324
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4211148 | https://www.ncbi.nlm.nih.gov/pubmed/4838694 | https://www.ncbi.nlm.nih.gov/pubmed/5882062 |

Nicofuranose is a niacin derivative used as a hypolipidemic agent. The Nicofuranose administration leads to inhibition of free fatty acid turnover and consequently a marked reduction in triglyceride turnover. Nicofuranose, unlike clofibrate, did not affect the mechanisms responsible for the clearance of plasma triglycerides.

Approval Year

PubMed

PubMed

Title	Date	PubMed
The mechanism of action of clofibrate and tetranicotinoylfructose (Bradilan) on the kinetics of plasma free fatty acid and triglyceride transport in type IV and type V hypertriglyceridaemia.	1974 Jun	4838694

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:20:39 GMT 2023` Edited by `admin` on `Fri Dec 15 15:20:39 GMT 2023`
Record UNII	GF99P6327K
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NICOFURANOSE

Official Name

English

ES 304

Code

English

NICOFURANOSE [MART.]

Common Name

English

ES-304

Code

English

D-FRUCTOFURANOSE 1,3,4,6-TETRANICOTINATE

Common Name

English

NICOFURANOSE [MI]

Common Name

English

nicofuranose [INN]

Common Name

English

Nicofuranose [WHO-DD]

Common Name

English

Classification Tree Code System Code

WHO-VATC

QC10AD03

Created by admin on Fri Dec 15 15:20:39 GMT 2023 , Edited by admin on Fri Dec 15 15:20:39 GMT 2023

WHO-ATC

C10AD03

Created by admin on Fri Dec 15 15:20:39 GMT 2023 , Edited by admin on Fri Dec 15 15:20:39 GMT 2023

NCI_THESAURUS

C98151

Created by admin on Fri Dec 15 15:20:39 GMT 2023 , Edited by admin on Fri Dec 15 15:20:39 GMT 2023

NCI_THESAURUS

C29707

Created by admin on Fri Dec 15 15:20:39 GMT 2023 , Edited by admin on Fri Dec 15 15:20:39 GMT 2023

Code System Code Type Description

NCI_THESAURUS

C83921

Created by admin on Fri Dec 15 15:20:39 GMT 2023 , Edited by admin on Fri Dec 15 15:20:39 GMT 2023

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WIKIPEDIA

NICOFURANOSE

Created by admin on Fri Dec 15 15:20:39 GMT 2023 , Edited by admin on Fri Dec 15 15:20:39 GMT 2023

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FDA UNII

GF99P6327K

Created by admin on Fri Dec 15 15:20:39 GMT 2023 , Edited by admin on Fri Dec 15 15:20:39 GMT 2023

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ECHA (EC/EINECS)

239-385-7

Created by admin on Fri Dec 15 15:20:39 GMT 2023 , Edited by admin on Fri Dec 15 15:20:39 GMT 2023

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RXCUI

104486

Created by admin on Fri Dec 15 15:20:39 GMT 2023 , Edited by admin on Fri Dec 15 15:20:39 GMT 2023

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RxNorm

EVMPD

SUB09237MIG

Created by admin on Fri Dec 15 15:20:39 GMT 2023 , Edited by admin on Fri Dec 15 15:20:39 GMT 2023

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INN

1565

Created by admin on Fri Dec 15 15:20:39 GMT 2023 , Edited by admin on Fri Dec 15 15:20:39 GMT 2023

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CAS

15351-13-0

Created by admin on Fri Dec 15 15:20:39 GMT 2023 , Edited by admin on Fri Dec 15 15:20:39 GMT 2023

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PUBCHEM

25495

Created by admin on Fri Dec 15 15:20:39 GMT 2023 , Edited by admin on Fri Dec 15 15:20:39 GMT 2023

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DRUG BANK

DB13422

Created by admin on Fri Dec 15 15:20:39 GMT 2023 , Edited by admin on Fri Dec 15 15:20:39 GMT 2023

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DRUG CENTRAL

1916

Created by admin on Fri Dec 15 15:20:39 GMT 2023 , Edited by admin on Fri Dec 15 15:20:39 GMT 2023

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ChEMBL

CHEMBL1697844

Created by admin on Fri Dec 15 15:20:39 GMT 2023 , Edited by admin on Fri Dec 15 15:20:39 GMT 2023

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MERCK INDEX

m843

Created by admin on Fri Dec 15 15:20:39 GMT 2023 , Edited by admin on Fri Dec 15 15:20:39 GMT 2023

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Merck Index

SMS_ID

100000084395

Created by admin on Fri Dec 15 15:20:39 GMT 2023 , Edited by admin on Fri Dec 15 15:20:39 GMT 2023

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EPA CompTox

DTXSID6023365

Created by admin on Fri Dec 15 15:20:39 GMT 2023 , Edited by admin on Fri Dec 15 15:20:39 GMT 2023

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MESH

C100123

Created by admin on Fri Dec 15 15:20:39 GMT 2023 , Edited by admin on Fri Dec 15 15:20:39 GMT 2023

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Related Record Type Details


					GF99P6327K

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