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Details

Stereochemistry ABSOLUTE
Molecular Formula C30H24N4O10
Molecular Weight 600.5324
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NICOFURANOSE

SMILES

O[C@]2(COC(=O)C1=CC=CN=C1)O[C@H](COC(=O)C3=CN=CC=C3)[C@@H](OC(=O)C4=CC=CN=C4)[C@@H]2OC(=O)C5=CC=CN=C5

InChI

InChIKey=FUWFSXZKBMCSKF-ZASNTINBSA-N
InChI=1S/C30H24N4O10/c35-26(19-5-1-9-31-13-19)40-17-23-24(42-28(37)21-7-3-11-33-15-21)25(43-29(38)22-8-4-12-34-16-22)30(39,44-23)18-41-27(36)20-6-2-10-32-14-20/h1-16,23-25,39H,17-18H2/t23-,24-,25+,30-/m1/s1

HIDE SMILES / InChI

Molecular Formula C30H24N4O10
Molecular Weight 600.5324
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Nicofuranose is a niacin derivative used as a hypolipidemic agent. The Nicofuranose administration leads to inhibition of free fatty acid turnover and consequently a marked reduction in triglyceride turnover. Nicofuranose, unlike clofibrate, did not affect the mechanisms responsible for the clearance of plasma triglycerides.

Approval Year

PubMed

Substance Class Chemical
Record UNII
GF99P6327K
Record Status Validated (UNII)
Record Version