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Details

Stereochemistry RACEMIC
Molecular Formula C3H7O6P.2Na.6H2O
Molecular Weight 324.1291
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM 1-GLYCEROPHOSPHATE HEXAHYDRATE

SMILES

O.O.O.O.O.O.[Na+].[Na+].OCC(O)COP([O-])([O-])=O

InChI

InChIKey=WYHXKNIXHCIVHR-UHFFFAOYSA-L
InChI=1S/C3H9O6P.2Na.6H2O/c4-1-3(5)2-9-10(6,7)8;;;;;;;;/h3-5H,1-2H2,(H2,6,7,8);;;6*1H2/q;2*+1;;;;;;/p-2

HIDE SMILES / InChI

Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C3H7O6P
Molecular Weight 170.0578
Charge -2
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description
Curator's Comment: description was created based on several sources, including: DOI: 10.1042/bj0280143 DOI: 10.1042/bj0280152 http://www.wikidoc.org/index.php/Glycerol_3-phosphate

Synthetic glycerophosphates have been known for many years and have been prepared in several ways. The acid may exist in two isomeric forms, alpha and beta. The L-a-acid is the naturally occurring form; the b-acid, present in hydrolyzates of lecithins from natural sources, arises from migration of the phosphoryl group from the a-carbon atom. Dehydrogenation of L-glycerol 3-phosphate produces Dihydroxyacetone phosphate and is part of the entry of glycerol (sourced from triglycerides) into the glycolytic pathway.

Originator

Curator's Comment: alpha-glycerophosphoric acid has long been known as a component of the lecithins and cephalins and may in a sense be looked on as a monoglyceride, the situation is much more favorable. Because of its great stability it has been possible for several workers to separate it from various phosphatides and free it from its accompanying beta-isomer. http://www.jbc.org/content/128/2/491.short

Approval Year

Targets

Targets

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
KABIVEN

Approved Use

It is indicated as a source of calories, protein, electrolytes and essential fatty acids for adult patients requiring parenteral nutrition when oral or enteral nutrition is not possible, insufficient, or contraindicated.

Launch Date

1.4088384E12
PubMed

PubMed

TitleDatePubMed
Patents

Patents

Sample Use Guides

19 to 38 mL/kg/day. The maximum infusion rate is 2.6 mL/kg/hour. Recommended infusion period is 12 to 24 hours.
Route of Administration: Intravenous
In Vitro Use Guide
Maximal ATP production in the presence of Ca2+ (200 nM) is obtained at 10 mM L-glycerol 3-phosphate in intact mitochondria from pancreatic B-cells.
Substance Class Chemical
Created
by admin
on Thu Jul 06 15:37:49 UTC 2023
Edited
by admin
on Thu Jul 06 15:37:49 UTC 2023
Record UNII
GER1329YB9
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SODIUM 1-GLYCEROPHOSPHATE HEXAHYDRATE
Common Name English
DISODIUM DL-.ALPHA.-GLYCEROPHOSPHATE HEXAHYDRATE
Common Name English
GLYCEROL, 1-(DIHYDROGEN PHOSPHATE), DISODIUM SALT, HEXAHYDRATE, DL-
Common Name English
1,2,3-PROPANETRIOL, 1-(DIHYDROGEN PHOSPHATE), DISODIUM SALT, HEXAHYDRATE, (±)-
Common Name English
1,2,3-PROPANETRIOL, 1-(DIHYDROGEN PHOSPHATE), SODIUM SALT, HYDRATE (1:2:6)
Systematic Name English
DISODIUM DL-GLYCEROL 3-PHOSPHATE HEXAHYDRATE
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID40955904
Created by admin on Thu Jul 06 15:37:49 UTC 2023 , Edited by admin on Thu Jul 06 15:37:49 UTC 2023
PRIMARY
PUBCHEM
43835013
Created by admin on Thu Jul 06 15:37:49 UTC 2023 , Edited by admin on Thu Jul 06 15:37:49 UTC 2023
PRIMARY
FDA UNII
GER1329YB9
Created by admin on Thu Jul 06 15:37:49 UTC 2023 , Edited by admin on Thu Jul 06 15:37:49 UTC 2023
PRIMARY
CAS
34363-28-5
Created by admin on Thu Jul 06 15:37:49 UTC 2023 , Edited by admin on Thu Jul 06 15:37:49 UTC 2023
PRIMARY
Related Record Type Details
ANHYDROUS->SOLVATE