BENZENESULFINIC ACID

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H6O2S
Molecular Weight	142.176
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OS(=O)C1=CC=CC=C1

InChI

InChIKey=JEHKKBHWRAXMCH-UHFFFAOYSA-N

InChI=1S/C6H6O2S/c7-9(8)6-4-2-1-3-5-6/h1-5H,(H,7,8)

HIDE SMILES / InChI

Molecular Formula	C6H6O2S
Molecular Weight	142.176
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
SOD1 Is Essential for the Viability of DT40 Cells and Nuclear SOD1 Functions as a Guardian of Genomic DNA.	2010-08-05	20811569
Nucleophilicity and nucleofugality of phenylsulfinate (PhSO(2)(-)): a key to understanding its ambident reactivity.	2010-04-07	20225879
Stereoselective synthesis and antiviral activity of (1E,2Z,3E)-1-(piperidin-1-yl)-1-(arylhydrazono)-2-[(benzoyl/benzothiazol-2-oyl)hydrazono]-4-(aryl(1))but-3-enes.	2010-03	20186867
Design and synthesis of a fluorescent probe for Zn2+, 5,7-bis(N,N-dimethylaminosulfonyl)-8-hydroxyquinoline-pendant 1,4,7,10-tetraazacyclododecane and Zn2+-dependent hydrolytic and Zn2+-independent photochemical reactivation of its benzenesulfonyl-caged derivative.	2010-02-01	20039701
The differential expression of aqueous soluble proteins in breast normal and cancerous tissues in relation to stage and grade of patients.	2010	21197096
New targets for the treatment of follicular lymphoma.	2009-12-23	20030851
Solid-phase synthesis and chemical properties of 2-(2-amino/hydroxyethyl)-1-aryl-3,4-dihydropyrazino[1, 2-b]indazol-2-iums.	2009-12-08	19961214
Benzhydryl phenyl sulfone.	2009-11-28	21578931
4,4'-Bis(dimethyl-amino)benzhydryl phenyl sulfone.	2009-11-07	21578770
Extracellular and intracellular polyphenol oxidases cause opposite effects on sensitivity of Streptomyces to phenolics: a case of double-edged sword.	2009-10-14	19826489
Versatile synthesis and rational design of caged morpholinos.	2009-09-23	19708646
Synthesis, antimalarial evaluation and molecular modeling studies of hydroxyethylpiperazines, potential aspartyl protease inhibitors, part 2.	2009-09	19403210
A 4-methylumbelliferone-based fluorescent probe for the sensitive detection of captopril.	2009-07	19050997
Novel furanylarylene arylsulfonylindolesulfonamides: synthesis and their antibacterial evaluation.	2009-06	19483339
Synthesis, reactivity, and kinetics of substitution in W3PdSe4 cuboidal clusters. A reexamination of the kinetics of substitution of the related W3S4 cluster with thiocyanate.	2009-04-20	19281203
Stereoselective formation of alpha-quaternary stereocenters in the Mannich reaction.	2009-04-16	19354318
Corrrelation of the specific rates of solvolysis of ethyl fluoroformate using the extended Grunwald-Winstein equation.	2009-03	19399229
Synthesis and anti-HIV-1 integrase activities of 3-aroyl-2,3-dihydro-1,1-dioxo-1,4,2-benzodithiazines.	2009-01	18394758
Reaction of the 4'-benzenesulfonyl derivatives of thymidine with organosilicon and organoaluminum reagents.	2009	19749230
Correlation of the rates of solvolysis of two arenesulfonyl chlorides and of trans-beta-styrenesulfonyl chloride - precursors in the development of new pharmaceuticals.	2008-12	19330098
Concerted solvent processes for common sulfonyl chloride precursors used in the synthesis of sulfonamide-based drugs.	2008-05	19325793
N'-[1-(2-Hydroxy-phen-yl)ethyl-idene]benzene-sulfonohydrazide.	2008-04-26	21202386
4-(Diethyl-amino)salicylaldehyde phenyl-sulfonyl-hydrazone.	2008-04-18	21202352
2-Acetyl-3-methyl-pyrazine phenyl-sulfonyl-hydrazone.	2008-04-10	21202316
Design and synthesis of a caged Zn2+ probe, 8-benzenesulfonyloxy-5-N,N-dimethylaminosulfonylquinolin-2-ylmethyl-pendant 1,4,7,10-tetraazacyclododecane, and its hydrolytic uncaging upon complexation with Zn2+.	2008-04-07	18321042
N'-(3-Ethoxy-2-hydroxybenzylidene)-benzenesulfonohydrazide.	2008-03-29	21202140
General preparation and controlled cyclization of acyclic terpenoids.	2008-03-07	18247490
Which are you watching, an individual reactive oxygen species or total oxidative stress?	2008	18596343
(1R,4R,7S)-1,7-Dimethyl-7-(phenyl-sulfonyl-meth-yl)spiro-[bicyclo-[2.2.1]heptane-2,2'-1,3-dioxolane].	2007-12-06	21200933
Palladium acetate-catalyzed cyclization reaction of 2,3-allenoic acids in the presence of simple allenes: an efficient synthesis of 4-(1'-bromoalk-2'(Z)-en-2'-yl)furan-2(5H)-one derivatives and the synthetic application.	2007-09-05	17691784
Prodrug-based design, synthesis, and biological evaluation of N-benzenesulfonylpiperidine derivatives as novel, orally active factor Xa inhibitors.	2007-06-15	17416533
Preclinical studies of TW-37, a new nonpeptidic small-molecule inhibitor of Bcl-2, in diffuse large cell lymphoma xenograft model reveal drug action on both Bcl-2 and Mcl-1.	2007-04-01	17404107
Further studies on the binding of N1-substituted tryptamines at h5-HT6 receptors.	2007-03-15	17239595
Analgesic agents without gastric damage: design and synthesis of structurally simple benzenesulfonanilide-type cyclooxygenase-1-selective inhibitors.	2007-01-15	17079150
Design of a practical fluorescent probe for superoxide based on protection-deprotection chemistry of fluoresceins with benzenesulfonyl protecting groups.	2007	17136791
Tandem Michael addition/amino-nitrile cyclization from 2-formyl-1,4-DHP in the synthesis of novel dihydroindolizine-based compounds.	2006-11-24	17109537
Total synthesis of (+/-)-magnofargesin.	2006-08-17	16898785
Stereocontrolled synthesis of the D- and L-glycero-beta-D-manno-heptopyranosides and their 6-deoxy analogues. Synthesis of methyl alpha-l-rhamno-pyranosyl-(1-->3)-D-glycero-beta-D-manno-heptopyranosyl- (1-->3)-6-deoxy-glycero-beta-D-manno-heptopyranosyl-(1-->4)-alpha-L- rhamno-pyranoside, a tetrasaccharide subunit of the lipopolysaccharide from Plesimonas shigelloides.	2006-06-21	16771524
Revisiting benzenesulfonyl linker for the deoxygenation and multifunctionalization of phenols.	2006-05-09	16676996
S,O-acetals as novel "chiral aldehyde" equivalents.	2006-03-01	16402397
Ab initio and DFT study of the geometric structures and static dipole (hyper)polarizabilities of aromatic anions.	2005-11-17	16833334
Polyfunctional tetrahydropyrido[2,3-b]pyrazine scaffolds from 4-phenylsulfonyl tetrafluoropyridine.	2005-11-11	16268611
tert-Butyl (phenylsulfonyl)alkyl-N-hydroxycarbamates: the first class of N-(Boc) nitrone equivalents.	2005-11-10	16268524
Solid-phase synthesis of 3,4-dihydro-1H-pyrimidine-2-ones using sodium benzenesulfinate as a traceless linker.	2005-09-13	16153067
A facile solid-phase synthesis of 1,2,4,5-tetrasubstituted imidazoles using sodium benzenesulfinate as a traceless linker.	2005-09-13	16153057
Aromatic-aromatic interaction of amitriptyline: implication of overdosed drug detoxification.	2005-02	15614810
Tandem Michael addition-carbene insertion reaction of 1-alkynyl(aryl)(tetrafluoroborato)-lambda3-bromanes: 1-(phenylsulfonyl)- and 1-(trifluoromethylsulfonyl)cyclopentene annulation.	2004-12-21	15599460
Mechanistic variations in the oxidation of Piloty's acid by metal complexes.	2004-11-29	15554653
Oligochitosan derivatives bearing electron-deficient aromatic rings for adsorption of amitriptyline: implications for drug detoxification.	2004-07-13	15244445
Design and synthesis of benzoic acid derivatives as influenza neuraminidase inhibitors using structure-based drug design.	1997-12-05	9406595

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:28:04 GMT 2025` Edited by `admin` on `Mon Mar 31 22:28:04 GMT 2025`
Record UNII	G9560D97PI
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BENZENESULFINIC ACID

Systematic Name

English

NSC-227915

Preferred Name

English

SAM-760 METABOLITE 1

Common Name

English

PHENYLSULFINIC ACID

Systematic Name

English

BENZENESULPHINIC ACID

Systematic Name

English

BENZENESULPHENIC ACID

Systematic Name

English

Code System Code Type Description

WIKIPEDIA

Phenylsulfinic acid