Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C18H19ClN4 |
| Molecular Weight | 326.823 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
ClC1=CC=C(C=C1)N2CCN(CC3=NN4C=CC=CC4=C3)CC2
InChI
InChIKey=DTRXURJDKOYCCD-UHFFFAOYSA-N
InChI=1S/C18H19ClN4/c19-15-4-6-17(7-5-15)22-11-9-21(10-12-22)14-16-13-18-3-1-2-8-23(18)20-16/h1-8,13H,9-12,14H2
| Molecular Formula | C18H19ClN4 |
| Molecular Weight | 326.823 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Reciprocal mutations in TM2/TM3 in a D2 dopamine receptor background confirms the importance of this microdomain as a selective determinant of para-halogenated 1,4-disubstituted aromatic piperazines. | 2005-06 |
|
| Certain 1,4-disubstituted aromatic piperidines and piperazines with extreme selectivity for the dopamine D4 receptor interact with a common receptor microdomain. | 2004-12 |
|
| FAUC 213, a highly selective dopamine D4 receptor full antagonist, exhibits atypical antipsychotic properties in behavioural and neurochemical models of schizophrenia. | 2004-08 |
|
| Attenuation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity by the novel selective dopamine D3-receptor partial agonist FAUC 329 predominantly in the nucleus accumbens of mice. | 2003-09-15 |
|
| Rationally based efficacy tuning of selective dopamine d4 receptor ligands leading to the complete antagonist 2-[4-(4-chlorophenyl)piperazin-1-ylmethyl]pyrazolo[1,5-a]pyridine (FAUC 213). | 2001-08-16 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 22:59:29 GMT 2025
by
admin
on
Mon Mar 31 22:59:29 GMT 2025
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| Record UNII |
G8F040299R
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| Record Status |
Validated (UNII)
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| Record Version |
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