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Details

Stereochemistry ACHIRAL
Molecular Formula C17H17FN4O
Molecular Weight 312.3415
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LUROSETRON

SMILES

CN1C2=C(C3=C1C(F)=CC=C3)C(=O)N(CC4=C(C)NC=N4)CC2

InChI

InChIKey=NUMKWGDDRWJQMY-UHFFFAOYSA-N
InChI=1S/C17H17FN4O/c1-10-13(20-9-19-10)8-22-7-6-14-15(17(22)23)11-4-3-5-12(18)16(11)21(14)2/h3-5,9H,6-8H2,1-2H3,(H,19,20)

HIDE SMILES / InChI

Molecular Formula C17H17FN4O
Molecular Weight 312.3415
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Lurosetron (GR 87442) is a serotonin 5HT3 receptor antagonist. It was undergoing clinical evaluation with Glaxo Wellcome in the UK as a potential drug for the treatment of emesis.

Approval Year

PubMed

PubMed

TitleDatePubMed
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:52:32 GMT 2023
Edited
by admin
on Fri Dec 15 16:52:32 GMT 2023
Record UNII
G694G740ZP
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LUROSETRON
INN  
INN  
Official Name English
lurosetron [INN]
Common Name English
GR-87442
Code English
1H-PYRIDO(4,3-B)INDOL-1-ONE, 6-FLUORO-2,3,4,5-TETRAHYDRO-5-METHYL-2-((5-METHYL-1H-IMIDAZOL-4-YL)METHYL)-
Systematic Name English
6-FLUORO-2,3,4,5-TETRAHYDRO-5-METHYL-2-((5-METHYLIMIDAZOL-4-YL)METHYL)-1H-PYRIDO(4,3-B)INDOL-1-ONE
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C94726
Created by admin on Fri Dec 15 16:52:32 GMT 2023 , Edited by admin on Fri Dec 15 16:52:32 GMT 2023
Code System Code Type Description
SMS_ID
100000082273
Created by admin on Fri Dec 15 16:52:32 GMT 2023 , Edited by admin on Fri Dec 15 16:52:32 GMT 2023
PRIMARY
CAS
128486-54-4
Created by admin on Fri Dec 15 16:52:32 GMT 2023 , Edited by admin on Fri Dec 15 16:52:32 GMT 2023
PRIMARY
INN
7096
Created by admin on Fri Dec 15 16:52:32 GMT 2023 , Edited by admin on Fri Dec 15 16:52:32 GMT 2023
PRIMARY
ChEMBL
CHEMBL2105137
Created by admin on Fri Dec 15 16:52:32 GMT 2023 , Edited by admin on Fri Dec 15 16:52:32 GMT 2023
PRIMARY
EVMPD
SUB08621MIG
Created by admin on Fri Dec 15 16:52:32 GMT 2023 , Edited by admin on Fri Dec 15 16:52:32 GMT 2023
PRIMARY
NCI_THESAURUS
C83896
Created by admin on Fri Dec 15 16:52:32 GMT 2023 , Edited by admin on Fri Dec 15 16:52:32 GMT 2023
PRIMARY
WIKIPEDIA
LUROSETRON
Created by admin on Fri Dec 15 16:52:32 GMT 2023 , Edited by admin on Fri Dec 15 16:52:32 GMT 2023
PRIMARY
PUBCHEM
172999
Created by admin on Fri Dec 15 16:52:32 GMT 2023 , Edited by admin on Fri Dec 15 16:52:32 GMT 2023
PRIMARY
FDA UNII
G694G740ZP
Created by admin on Fri Dec 15 16:52:32 GMT 2023 , Edited by admin on Fri Dec 15 16:52:32 GMT 2023
PRIMARY
EPA CompTox
DTXSID30155911
Created by admin on Fri Dec 15 16:52:32 GMT 2023 , Edited by admin on Fri Dec 15 16:52:32 GMT 2023
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY