Daretabart

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 21:00:12 GMT 2025` Edited by `admin` on `Wed Apr 02 21:00:12 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1\|KAPPA
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	G3JN6K8LV3
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Daretabart

Official Name

English

H-gamma1 heavy chain (1-443) [VH Musmus/Homsap (Mus musculus IGHV1-42*04 (86.5%) -(IGHD) -IGHJ4*01 (71.4%) Q120>T (105), G121>Q (106), T122>G (107) /Homo sapiens IGHV1-46*01 (71.9%) -(IGHD) -IGHJ5*01 (75.0%) Q120>T (105), G121>Q (106), T122>G (107), L123

Preferred Name

English

Immunoglobulin G1 [318-alanine], anti-(human ganglioside GD2) (human-Mus musculus monoclonal RPL001 ?1-chain), disulfide with human-Mus musculus monoclonal RPL001 ?-chain, dimer

Common Name

English

immunoglobulin G1-kappa, anti-[Homo sapiens GD2 (disialoganglioside GD2)], monoclonal antibody;

Common Name

English

daretabart [INN]

Common Name

English

Code System Code Type Description

FDA UNII

G3JN6K8LV3

Created by admin on Wed Apr 02 21:00:12 GMT 2025 , Edited by admin on Wed Apr 02 21:00:12 GMT 2025

PRIMARY

CAS

3011830-62-6

Created by admin on Wed Apr 02 21:00:12 GMT 2025 , Edited by admin on Wed Apr 02 21:00:12 GMT 2025

PRIMARY

INN

13434

Created by admin on Wed Apr 02 21:00:12 GMT 2025 , Edited by admin on Wed Apr 02 21:00:12 GMT 2025

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_140	2_196
2_216	4_220
2_257	2_317
1_140	1_196
2_363	2_421
3_23	3_93
3_140	3_200
4_23	4_93
4_140	4_200
1_216	3_220
1_222	2_222
1_225	2_225
1_257	1_317
1_363	1_421

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_293
N	2_293

Related Record Type Details


					FUI2V09E1C

DISIALOGANGLIOSIDE GD-2

TARGET->LIGAND

Amount:

Related Record Type Details


					G3JN6K8LV3

Daretabart

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_443] [2_443]	C-TERMINUS	K		LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL