BRILLIANT GREEN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C27H33N2.HO4S
Molecular Weight	482.635
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OS([O-])(=O)=O.CCN(CC)C1=CC=C(C=C1)C(C2=CC=CC=C2)=C3C=CC(C=C3)=[N+](CC)CC

InChI

InChIKey=NNBFNNNWANBMTI-UHFFFAOYSA-M

InChI=1S/C27H33N2.H2O4S/c1-5-28(6-2)25-18-14-23(15-19-25)27(22-12-10-9-11-13-22)24-16-20-26(21-17-24)29(7-3)8-4;1-5(2,3)4/h9-21H,5-8H2,1-4H3;(H2,1,2,3,4)/q+1;/p-1

HIDE SMILES / InChI

Molecular Formula	HO4S
Molecular Weight	97.071
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C27H33N2
Molecular Weight	385.5643
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.valentis.com/uploads/shop/docs/66_0115e26e32e821ae73e9ef60a3270328.pdf

Brilliant green is a synthetic dye. Brilliant green inhibits the growth of gram-positive bacterias and thus has antibacterial properties. It is broadly used as a topical antiseptic (in form of cutaneous solution), especially in Russia and Eastern Europe.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Bacteial cells growth 2 Target ID: Bacteial cells growth Sources: https://www.ncbi.nlm.nih.gov/pubmed/13416511	Inhibitor 8504

Conditions

Condition	Modality	Targets	Highest Phase	Product
Bacterial infections 235 Sources: https://www.ncbi.nlm.nih.gov/pubmed/17866691	Preventing		Approved 8583	BRILLIANT GREEN Approved Use Brilliant green is used as antiseptic for skin abrasions and scratches; to mark the intended section place before the surgical operation.
Umbilical cord area infection in newborn 2 Sources: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=44e0306a-2c14-4cc3-9ac1-218c0c8b15a0	Preventing		Approved 8583	KERR 100 TRIPLE DYE Approved Use Aids in the prevention of infection in the umbilical cord area of newborn.

PubMed

Title	Date	PubMed
Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.	2011-07-14	21599003
Effect of brilliant green on the motility of Salmonellae and other selected microorganisms.	1969-10	4983955
EFFECT OF VARIOUS CONCENTRATIONS OF BRILLIANT GREEN AND BILE SALTS ON SALMONELLAE AND OTHER MICROORGANISMS.	1965-01	14264851
Use of crystal violet or brilliant green dyes for the determination of Salmonellae in dried food products.	1960-12	13729626
A Note on the Value of Brilliant Green as an Antiseptic.	1917-06-30	20768638

Patents

Sample Use Guides

In Vivo Use Guide

Apply to the affected area using cotton swabs or gauze pads.

Route of Administration: Topical

In Vitro Use Guide

Staphylococcus aureus strain was treated with brilliant green at final concentration of 8.8*10(-4) M. At this concentration the drug inhibited the cells growth by 50%.

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:26:24 GMT 2025` Edited by `admin` on `Mon Mar 31 21:26:24 GMT 2025`
Record UNII	G0L543D370
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BASIC GREEN 1

Preferred Name

English

BRILLIANT GREEN

Common Name

English

BRILLIANT GREEN [MI]

Common Name

English

BRILLIANT GREEN [MART.]

Common Name

English

NSC-5011

Code

English

BRILLIANT GREEN [VANDF]

Common Name

English

(4-(4-(DIETHYLAMINO)BENZHYDRYLENE)CYCLOHEXA-2,5-DIEN-1-YLIDENE)DIETHYLAMMONIUM HYDROGEN SULPHATE

Common Name

English

Brilliant green ci 42040 [WHO-DD]

Common Name

English

(4-(4-(DIETHYLAMINO)BENZHYDRYLENE)CYCLOHEXA-2,5-DIEN-1-YLIDENE)DIETHYLAMMONIUM HYDROGEN SULFATE

Common Name

English

MALACHITE GREEN G

Common Name

English

C.I. BASIC GREEN 1

Common Name

English

C.I. BASIC GREEN 1 [HSDB]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C461