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Details

Stereochemistry ACHIRAL
Molecular Formula C27H33N2.HO4S
Molecular Weight 482.635
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BRILLIANT GREEN

SMILES

OS([O-])(=O)=O.CCN(CC)C1=CC=C(C=C1)C(C2=CC=CC=C2)=C3C=CC(C=C3)=[N+](CC)CC

InChI

InChIKey=NNBFNNNWANBMTI-UHFFFAOYSA-M
InChI=1S/C27H33N2.H2O4S/c1-5-28(6-2)25-18-14-23(15-19-25)27(22-12-10-9-11-13-22)24-16-20-26(21-17-24)29(7-3)8-4;1-5(2,3)4/h9-21H,5-8H2,1-4H3;(H2,1,2,3,4)/q+1;/p-1

HIDE SMILES / InChI
Molecular Formula HO4S
Molecular Weight 97.071
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C27H33N2
Molecular Weight 385.5643
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Brilliant green is a synthetic dye. Brilliant green inhibits the growth of gram-positive bacterias and thus has antibacterial properties. It is broadly used as a topical antiseptic (in form of cutaneous solution), especially in Russia and Eastern Europe.

Approval Year

1960
107
Targets

Targets

Primary TargetPharmacologyConditionPotency
Inhibitor
8297
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
Approved
8429
BRILLIANT GREEN

Approved Use

Brilliant green is used as antiseptic for skin abrasions and scratches; to mark the intended section place before the surgical operation.
Preventing
Approved
8429
KERR 100 TRIPLE DYE

Approved Use

Aids in the prevention of infection in the umbilical cord area of newborn.
PubMed

PubMed

TitleDatePubMed
A Note on the Value of Brilliant Green as an Antiseptic.
1917 Jun 30
EFFECT OF VARIOUS CONCENTRATIONS OF BRILLIANT GREEN AND BILE SALTS ON SALMONELLAE AND OTHER MICROORGANISMS.
1965 Jan
Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.
2011 Jul 14
Patents

Patents

20010021383
2
20010043999
2
JP2001342374A
2
JP2001510773A
10
JP2007511313A
23
JP2014198039A
2
JPH03254623A
2
JPH04232457A
2
JPS5686983A
2

Sample Use Guides

In Vivo Use Guide
Apply to the affected area using cotton swabs or gauze pads.
Route of Administration: Topical
In Vitro Use Guide
Staphylococcus aureus strain was treated with brilliant green at final concentration of 8.8*10(-4) M. At this concentration the drug inhibited the cells growth by 50%.
Substance Class Chemical
Created
by admin
on Sat Dec 16 05:08:14 GMT 2023
Edited
by admin
on Sat Dec 16 05:08:14 GMT 2023
Record UNII
G0L543D370
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BRILLIANT GREEN
MART.   MI   VANDF  
Common Name English
BRILLIANT GREEN [MI]
Common Name English
BASIC GREEN 1
INCI  
INCI  
Official Name English
BRILLIANT GREEN [MART.]
Common Name English
NSC-5011
Code English
BRILLIANT GREEN [VANDF]
Common Name English
(4-(4-(DIETHYLAMINO)BENZHYDRYLENE)CYCLOHEXA-2,5-DIEN-1-YLIDENE)DIETHYLAMMONIUM HYDROGEN SULPHATE
Common Name English
Brilliant green ci 42040 [WHO-DD]
Common Name English
(4-(4-(DIETHYLAMINO)BENZHYDRYLENE)CYCLOHEXA-2,5-DIEN-1-YLIDENE)DIETHYLAMMONIUM HYDROGEN SULFATE
Common Name English
MALACHITE GREEN G
Common Name English
C.I. BASIC GREEN 1
HSDB  
Common Name English
BASIC GREEN 1 [INCI]
Common Name English
C.I. BASIC GREEN 1 [HSDB]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C461
Created by admin on Sat Dec 16 05:08:14 GMT 2023 , Edited by admin on Sat Dec 16 05:08:14 GMT 2023
Code System Code Type Description
RXCUI
19698
Created by admin on Sat Dec 16 05:08:14 GMT 2023 , Edited by admin on Sat Dec 16 05:08:14 GMT 2023
PRIMARY RxNorm
WIKIPEDIA
Brilliant green (dye)
Created by admin on Sat Dec 16 05:08:14 GMT 2023 , Edited by admin on Sat Dec 16 05:08:14 GMT 2023
PRIMARY
HSDB
6403
Created by admin on Sat Dec 16 05:08:14 GMT 2023 , Edited by admin on Sat Dec 16 05:08:14 GMT 2023
PRIMARY
CHEBI
88173
Created by admin on Sat Dec 16 05:08:14 GMT 2023 , Edited by admin on Sat Dec 16 05:08:14 GMT 2023
PRIMARY
EPA CompTox
DTXSID1048700
Created by admin on Sat Dec 16 05:08:14 GMT 2023 , Edited by admin on Sat Dec 16 05:08:14 GMT 2023
PRIMARY
CAS
633-03-4
Created by admin on Sat Dec 16 05:08:14 GMT 2023 , Edited by admin on Sat Dec 16 05:08:14 GMT 2023
PRIMARY
NCI_THESAURUS
C83560
Created by admin on Sat Dec 16 05:08:14 GMT 2023 , Edited by admin on Sat Dec 16 05:08:14 GMT 2023
PRIMARY
DRUG CENTRAL
4665
Created by admin on Sat Dec 16 05:08:14 GMT 2023 , Edited by admin on Sat Dec 16 05:08:14 GMT 2023
PRIMARY
MERCK INDEX
m2650
Created by admin on Sat Dec 16 05:08:14 GMT 2023 , Edited by admin on Sat Dec 16 05:08:14 GMT 2023
PRIMARY Merck Index
FDA UNII
G0L543D370
Created by admin on Sat Dec 16 05:08:14 GMT 2023 , Edited by admin on Sat Dec 16 05:08:14 GMT 2023
PRIMARY
ECHA (EC/EINECS)
211-190-1
Created by admin on Sat Dec 16 05:08:14 GMT 2023 , Edited by admin on Sat Dec 16 05:08:14 GMT 2023
PRIMARY
MESH
C006798
Created by admin on Sat Dec 16 05:08:14 GMT 2023 , Edited by admin on Sat Dec 16 05:08:14 GMT 2023
PRIMARY
DRUG BANK
DBSALT002749
Created by admin on Sat Dec 16 05:08:14 GMT 2023 , Edited by admin on Sat Dec 16 05:08:14 GMT 2023
PRIMARY
EVMPD
SUB13121MIG
Created by admin on Sat Dec 16 05:08:14 GMT 2023 , Edited by admin on Sat Dec 16 05:08:14 GMT 2023
PRIMARY
NSC
5011
Created by admin on Sat Dec 16 05:08:14 GMT 2023 , Edited by admin on Sat Dec 16 05:08:14 GMT 2023
PRIMARY
SMS_ID
100000092522
Created by admin on Sat Dec 16 05:08:14 GMT 2023 , Edited by admin on Sat Dec 16 05:08:14 GMT 2023
PRIMARY
DAILYMED
G0L543D370
Created by admin on Sat Dec 16 05:08:14 GMT 2023 , Edited by admin on Sat Dec 16 05:08:14 GMT 2023
PRIMARY
PUBCHEM
12449
Created by admin on Sat Dec 16 05:08:14 GMT 2023 , Edited by admin on Sat Dec 16 05:08:14 GMT 2023
PRIMARY
Related Record Type Details
Structure of BRILLIANT GREEN CATION
ACTIVE MOIETY
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
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