DOBUPRIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H30ClN3O4
Molecular Weight	411.923
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCOC1=C(C=C(Cl)C(N)=C1)C(=O)NC2CCN(CC3OCCO3)CC2

InChI

InChIKey=BTBFXLRQGPHRGT-UHFFFAOYSA-N

InChI=1S/C20H30ClN3O4/c1-2-3-8-26-18-12-17(22)16(21)11-15(18)20(25)23-14-4-6-24(7-5-14)13-19-27-9-10-28-19/h11-12,14,19H,2-10,13,22H2,1H3,(H,23,25)

HIDE SMILES / InChI

Molecular Formula	C20H30ClN3O4
Molecular Weight	411.923
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/8580158 | https://www.medchemexpress.com/Dobupride.html

Dobupride is a substituted benzamide drug, which has shown powerful gastroprokinetic activity in animal studies, inducing gastric emptying and intestinal motility and increasing the resting pressure of the lower oesophageal sphincter. Compared with metoclopramide, both drugs increased stomach emptying of liquid and also increased the lower oesophageal sphincter pressure, but after metoclopramide administration more adverse effects (such as anxiety, drowsiness, and sweating) were reported.

Approval Year

PubMed

Title	Date	PubMed
Dobupride--what exactly is its degradation behavior?	1997 Jul	9260678

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:28:30 GMT 2023` Edited by `admin` on `Fri Dec 15 15:28:30 GMT 2023`
Record UNII	FW0Z2U7O23
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DOBUPRIDE

Official Name

English

dobupride [INN]

Common Name

English

4-AMINO-2-BUTOXY-5-CHLORO-N-(1-(1,3-DIOXOLAN-2-YLMETHYL)-4-PIPERIDYL)BENZAMIDE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29710