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Details

Stereochemistry RACEMIC
Molecular Formula C5H10O10P2.H2O
Molecular Weight 310.0897
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BUTEDRONIC ACID MONOHYDRATE

SMILES

O.OC(=O)CC(C(P(O)(O)=O)P(O)(O)=O)C(O)=O

InChI

InChIKey=LXTJOCAAYQSEGD-UHFFFAOYSA-N
InChI=1S/C5H10O10P2.H2O/c6-3(7)1-2(4(8)9)5(16(10,11)12)17(13,14)15;/h2,5H,1H2,(H,6,7)(H,8,9)(H2,10,11,12)(H2,13,14,15);1H2

HIDE SMILES / InChI

Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C5H10O10P2
Molecular Weight 292.0744
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

PubMed

PubMed

TitleDatePubMed
The assessment of bee venom responses in an experimental model of mono-arthritis using Tc-99m DPD bone scintigraphy.
2010-07
[Diagnosis of senile cardiac amyloidosis by (99m)Tc-DPD scintigraphy].
2009-04
[Nuclear medical imaging in case of painful knee arthroplasty].
2009-01
[Detection of bone metastasis of prostate cancer - comparison of whole-body MRI and bone scintigraphy].
2008-08
Usefulness of 99mTc-DPD scintigraphy in cardiac amyloidosis.
2008-04-15
Labeling, characterization, and in vivo localization of a new 90Y-based phosphonate chelate 2,3-dicarboxypropane-1,1-diphosphonic acid for the treatment of bone metastases: Comparison with 99mTc-DPD complex.
2008-04-15
[Transient osteoporosis of the hip in pregnancy. Successful treatment with calcitonin: a case report].
2007-10
Bone scintigraphy as a prognostic indicator for bone collapse in the early phases of femoral head osteonecrosis.
2007-06
Gastric accumulation of bone seeking agent in a patient with advanced gastric cancer.
2007-02
Puzzling intestinal uptake in 99mTc-DPD bone scintigraphy.
2006
Noninvasive etiologic diagnosis of cardiac amyloidosis using 99mTc-3,3-diphosphono-1,2-propanodicarboxylic acid scintigraphy.
2005-09-20
Comparison of the effect of 99mTc-DPD and 99mTc-MDP on experimentally-induced osteoarthritis in the stifle joint of the dog.
2005-07-08
Alteration of the organ uptake of the (99m)Tc-radiopharmaceuticals, (99m)Tc-DPD, (99m)Tc-DMSA, (99m)Tc-tin colloid and (99m)Tc-MAA, induced by the applied cytotoxic drugs methotrexate sodium and cyclophosphamide.
2005-05
Whole body bone scintigraphy after parachute accident.
2005-02
Tc-99m DPD uptake in the thigh from metastasis of adenocarcinoma of the rectum.
2005-01
Assessment of aseptic loosening of the acetabular component in a total hip replacement with 99mTc-DPD-SPECT/spiral-CT hybrid imaging.
2005
[TierSPECT: performance of a dedicated small-animal-SPECT camera and first in vivo measurements].
2005
Bone lesion detection with carrier-added 99mTc-EDTMP in comparison with 99mTc-DPD.
2004-04
Chemical and biological evaluation of technetium (I) tricarbonyl complexes with EHIDA and DPD. 99m (I) complexes of EHIDA and DPD.
2004
Unusual bilateral Tc-99m DPD uptake on bone scan.
2003-11
[Stress fracture of the sacrum in a professional basketball athlete].
2003-04
Bone scintigraphy using Tc-99m DPD and F18-FDG in a patient with SAPHO syndrome.
2003
Monostotic Paget's Disease of a cervical vertebra: differential diagnosis with F-18 FDG positron emission tomography using a coincidence technique and with Tc-99m dicarboxypropane diphosphonate.
2002-07
99mTc-DPD scintigraphy in transthyretin-related familial amyloidotic polyneuropathy.
2002-03
Bone pain with scintigraphy suggestive of widespread metastases--do not forget phosphate.
2002-03
Bone infarction resulting from parosteal soft tissue angiosarcoma.
2002-01
Skeletal scintigraphy in acquired adult Fanconi syndrome.
2002-01
Substance Class Chemical
Created
by admin
on Mon Mar 31 22:57:36 GMT 2025
Edited
by admin
on Mon Mar 31 22:57:36 GMT 2025
Record UNII
FS01746YVI
Record Status Validated (UNII)
Record Version
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Name Type Language
BUTEDRONIC ACID MONOHYDRATE
MI  
Common Name English
BUTEDRONIC ACID MONOHYDRATE [MI]
Preferred Name English
2-(DIPHOSPHONOMETHYL)BUTANEDIOIC ACID HYDRATE
Systematic Name English
Code System Code Type Description
FDA UNII
FS01746YVI
Created by admin on Mon Mar 31 22:57:36 GMT 2025 , Edited by admin on Mon Mar 31 22:57:36 GMT 2025
PRIMARY
MERCK INDEX
m2790
Created by admin on Mon Mar 31 22:57:36 GMT 2025 , Edited by admin on Mon Mar 31 22:57:36 GMT 2025
PRIMARY Merck Index
PUBCHEM
88745907
Created by admin on Mon Mar 31 22:57:36 GMT 2025 , Edited by admin on Mon Mar 31 22:57:36 GMT 2025
PRIMARY
Related Record Type Details
ANHYDROUS->SOLVATE