DZ-2640

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C22H29N3O6S
Molecular Weight	463.547
Optical Activity	UNSPECIFIED
Defined Stereocenters	5 / 5
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]12[C@@H]([C@@H](C)O)C(=O)N1C(C(=O)OCOC(=O)C(C)(C)C)=C(S[C@@H]3CN4C=CN=C4C3)[C@@H]2C

InChI

InChIKey=SVIXKYNOOFZUFA-CNRIWFPOSA-N

InChI=1S/C22H29N3O6S/c1-11-16-15(12(2)26)19(27)25(16)17(20(28)30-10-31-21(29)22(3,4)5)18(11)32-13-8-14-23-6-7-24(14)9-13/h6-7,11-13,15-16,26H,8-10H2,1-5H3/t11-,12-,13+,15-,16-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C22H29N3O6S
Molecular Weight	463.547
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	5 / 5
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 10:22:26 GMT 2023` Edited by `admin` on `Sat Dec 16 10:22:26 GMT 2023`
Record UNII	FN8NM9XR4K
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DZ-2640

Code

English

1-AZABICYCLO(3.2.0)HEPT-2-ENE-2-CARBOXYLIC ACID, 3-((6,7-DIHYDRO-5H-PYRROLO(1,2-A)IMIDAZOL-6-YL)THIO)-6-(1-HYDROXYETHYL)-4-METHYL-7-OXO-, (2,2-DIMETHYL-1-OXOPROPOXY)METHYL ESTER, (4R-(3(S*),4.ALPHA.,5.BETA.,6.BETA.(R*)))-

Systematic Name

English

1-AZABICYCLO(3.2.0)HEPT-2-ENE-2-CARBOXYLIC ACID, 3-(((6S)-6,7-DIHYDRO-5H-PYRROLO(1,2-A)IMIDAZOL-6-YL)THIO)-6-((1R)-1-HYDROXYETHYL)-4-METHYL-7-OXO-, (2,2-DIMETHYL-1-OXOPROPOXY)METHYL ESTER, (4R,5S,6S)-

Systematic Name

English

DZ2640

Code

English

Code System Code Type Description

FDA UNII

FN8NM9XR4K

Created by admin on Sat Dec 16 10:22:26 GMT 2023 , Edited by admin on Sat Dec 16 10:22:26 GMT 2023

PRIMARY

PUBCHEM

9804440

Created by admin on Sat Dec 16 10:22:26 GMT 2023 , Edited by admin on Sat Dec 16 10:22:26 GMT 2023

PRIMARY

CAS

184633-88-3

Created by admin on Sat Dec 16 10:22:26 GMT 2023 , Edited by admin on Sat Dec 16 10:22:26 GMT 2023

PRIMARY

Related Record Type Details


					VL8A7ME6X8

DU-6681

METABOLITE ACTIVE -> PRODRUG

Comments:

DZ-2640 is the ester-type oral carbapenem prodrug of an active parent compound, DU-6681. The pharmacokinetics and safety of DU-6681 were investigated in six studies after oral administration of a single dose of DZ-2640 to healthy male Japanese volunteers at doses of 25, 50, 100, 200, and 400 mg (as the equivalents of DU-6681) in the fasted state.

Related Record Type Details


					FN8NM9XR4K

DZ-2640

ACTIVE MOIETY