U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
139594
Substance Class Protein
Created
by admin
on Sat Dec 16 10:16:55 GMT 2023
Edited
by admin
on Sat Dec 16 10:16:55 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
FE7L22H028
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ZALIFRELIMAB
INN   USAN  
Official Name English
Zalifrelimab [WHO-DD]
Common Name English
UGN-301
Code English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS CTLA4 (CYTOTOXIC TLYMPHOCYTE-ASSOCIATED PROTEIN 4, CD152))
Common Name English
A HUMAN MONOCLONAL ANTIBODY TARGETING CYTOTOXIC T LYMPHOCYTE ASSOCIATED PROTEIN 4 (CTLA4)
Common Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4) (HUMAN MONOCLONAL AGEN1884 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL AGEN1884 .KAPPA.-CHAIN, DIMER
Common Name English
zalifrelimab [INN]
Common Name English
AGEN-1884
Common Name English
AGEN1884
Code English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS CYTOTOXIC T-LYMPHOCYTE PROTEIN 4 (CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED ANTIGEN 4CTLA-4CD152 ANTIGEN))HUMAN MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN HOMO SAPIENS (1-448) (HOMO SAPIENS VH (IGHV3-21*01 (IGHD)-IGHJ3*02
Common Name English
ZALIFRELIMAB [USAN]
Common Name English
ANTI-CTLA-4 MONOCLONAL ANTIBODY AGEN1884
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C129822
Created by admin on Sat Dec 16 10:16:55 GMT 2023 , Edited by admin on Sat Dec 16 10:16:55 GMT 2023
NCI_THESAURUS C128036
Created by admin on Sat Dec 16 10:16:55 GMT 2023 , Edited by admin on Sat Dec 16 10:16:55 GMT 2023
Code System Code Type Description
DRUG BANK
DB15632
Created by admin on Sat Dec 16 10:16:55 GMT 2023 , Edited by admin on Sat Dec 16 10:16:55 GMT 2023
PRIMARY
FDA UNII
FE7L22H028
Created by admin on Sat Dec 16 10:16:55 GMT 2023 , Edited by admin on Sat Dec 16 10:16:55 GMT 2023
PRIMARY
CAS
2030414-11-8
Created by admin on Sat Dec 16 10:16:55 GMT 2023 , Edited by admin on Sat Dec 16 10:16:55 GMT 2023
NO STRUCTURE GIVEN
USAN
HI-67
Created by admin on Sat Dec 16 10:16:55 GMT 2023 , Edited by admin on Sat Dec 16 10:16:55 GMT 2023
PRIMARY
CAS
2148321-69-9
Created by admin on Sat Dec 16 10:16:55 GMT 2023 , Edited by admin on Sat Dec 16 10:16:55 GMT 2023
PRIMARY
INN
10994
Created by admin on Sat Dec 16 10:16:55 GMT 2023 , Edited by admin on Sat Dec 16 10:16:55 GMT 2023
PRIMARY
NCI_THESAURUS
C126113
Created by admin on Sat Dec 16 10:16:55 GMT 2023 , Edited by admin on Sat Dec 16 10:16:55 GMT 2023
PRIMARY
From To
1_22 1_96
2_22 2_96
2_145 2_201
2_221 4_214
2_262 2_322
1_145 1_201
2_368 2_426
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
1_221 3_214
1_227 2_227
1_230 2_230
1_262 1_322
1_368 1_426
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_298
N 2_298
Related Record Type Details
CYTOTOXIC T-LYMPHOCYTE PROTEIN 4
TARGET -> INHIBITOR
Related Record Type Details
ZALIFRELIMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
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DISCLAIMER
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