SU-9516

COC1=CC2=C(NC(=O)\C2=C/C3=CN=CN3)C=C1

InChIKey=QNUKRWAIZMBVCU-WCIBSUBMSA-N

InChI=1S/C13H11N3O2/c1-18-9-2-3-12-10(5-9)11(13(17)16-12)4-8-6-14-7-15-8/h2-7H,1H3,(H,14,15)(H,16,17)/b11-4-

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Potency
Cyclin-dependent kinase 2 22 Target ID: CHEMBL301 Sources: https://www.ncbi.nlm.nih.gov/pubmed/16584130	Inhibitor 8297	35.0 nM [IC50]
Cyclin-dependent kinase 5 8 Target ID: CHEMBL4036 Sources: https://www.ncbi.nlm.nih.gov/pubmed/16584130	Inhibitor 8297	65.0 nM [IC50]
Cyclin-dependent kinase 4 22 Target ID: CHEMBL331 Sources: https://www.ncbi.nlm.nih.gov/pubmed/24417566	Inhibitor 8297	200.0 nM [IC50]
Vascular endothelial growth factor receptor 2 104 Target ID: CHEMBL279 Sources: https://www.ncbi.nlm.nih.gov/pubmed/12749903	Inhibitor 8297	130.0 nM [IC50]
Cyclin-dependent kinase 1 27 Target ID: CHEMBL308 Sources: https://www.ncbi.nlm.nih.gov/pubmed/24417566	Inhibitor 8297	40.0 nM [IC50]

Substance Class	Chemical Created by `admin` on `Sat Dec 16 05:26:19 GMT 2023` Edited by `admin` on `Sat Dec 16 05:26:19 GMT 2023`
Record UNII	FD2SWT2SDI
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

SU-9516

Code

English

2H-INDOL-2-ONE, 1,3-DIHYDRO-3-(1H-IMIDAZOL-5-YLMETHYLENE)-5-METHOXY-, (3Z)-

Systematic Name

English

SU9516

Common Name

English

(3Z)-1,3-DIHYDRO-3-(1H-IMIDAZOL-5-YLMETHYLENE)-5-METHOXY-2H-INDOL-2-ONE

Systematic Name

English

Code System Code Type Description

CAS

377090-84-1