U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Tue Apr 01 23:50:56 GMT 2025
Edited
by admin
on Tue Apr 01 23:50:56 GMT 2025
Protein Type ENZYME
Protein Sub Type SERINE/THREONINE-PROTEIN KINASE
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
IEQ8K30M47
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CYCLIN-DEPENDENT KINASE 2
Common Name English
CDKN2
Preferred Name English
P33 PROTEIN KINASE
Common Name English
CDK2
Common Name English
CELL DIVISION PROTEIN KINASE 2
Common Name English
Code System Code Type Description
FDA UNII
IEQ8K30M47
Created by admin on Tue Apr 01 23:50:56 GMT 2025 , Edited by admin on Tue Apr 01 23:50:56 GMT 2025
PRIMARY
UNIPROT
P24941
Created by admin on Tue Apr 01 23:50:56 GMT 2025 , Edited by admin on Tue Apr 01 23:50:56 GMT 2025
PRIMARY
Related Record Type Details
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The development of bronchopulmonary hemorrhage and sepsis resulted in the death of two patients. The study was ultimately terminated prematurely due to an unfavorable risk-benefit ratio in patients.
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Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
AMINO_ACID_SUBSTITUTION [1_14] [1_160] SITE_SPECIFIC THREONINE PHOSPHATE 3L4WX7B1EI
AMINO_ACID_SUBSTITUTION [1_15] [1_19] SITE_SPECIFIC TYROSINE O-PHOSPHATE 2R86C98KDX
AMINO_ACID_SUBSTITUTION [1_6] SITE_SPECIFIC N6-ACETYLLYSINE 470AD5VY1X
AMINO_ACID_SUBSTITUTION [1_1] SITE_SPECIFIC N-ACETYLMETHIONINE 9J12WX5B6A
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL