Approval Year
| Substance Class |
Structurally Diverse
Created
by
admin
on
Edited
Wed Apr 02 19:21:35 GMT 2025
by
admin
on
Wed Apr 02 19:21:35 GMT 2025
|
| Source Materials Class | ORGANISM |
| Source Materials Type | AUTOLOGOUS HUMAN |
| Source Materials State | LIVE GENETICALLY MODIFIED |
| Source Materials Parent | |
| Part | BLOOD |
| Fraction Material Type | CELL |
| Fraction Name | CD3+ enriched T cells |
| Record UNII |
FB64K38TE2
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Preferred Name | English | ||
|
Official Name | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
13539
Created by
admin on Wed Apr 02 19:21:35 GMT 2025 , Edited by admin on Wed Apr 02 19:21:35 GMT 2025
|
PRIMARY | |||
|
FB64K38TE2
Created by
admin on Wed Apr 02 19:21:35 GMT 2025 , Edited by admin on Wed Apr 02 19:21:35 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
TARGET->CYTOTOXIC T-CELL |
|
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
ACTIVE MOIETY |
|
Agent Modifications
| Modification Process | Modification Role | Modification Type | Amount | Fragment Name | Fragment ID |
|---|---|---|---|---|---|
| LENTIVIRAL TRANSFECTION | TRANSFECTION | GENE MODIFICATION | Talicabtagene autoleucel lentiviral vector | XYJ4596Q2U | |
| CULTURE | ACTIVATOR | BIOLOGICAL | T CELL TRANSACT, HUMAN | YG578HEY4V | |
| CULTURE | EXPANSION | BIOLOGICAL |
|
ALDESLEUKIN | M89N0Q7EQR |
Structural Modifications
| Modification Type | Location Site | Location Type | Residue Modified | Extent | Fragment Name | Fragment Approval |
|---|---|---|---|---|---|---|
| VECTOR EXPRESSED PROTEIN | Talicabtagene autoleucel expressed chimeric antigen receptor (CAR) targeting CD19 | GWA9BV7FQD | ||||
| INSERTED GENE EXPRESSION VECTOR | Talicabtagene autoleucel transgene insert | W27MEN4E3D |