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Details

Stereochemistry ACHIRAL
Molecular Formula C8H7O3.Na
Molecular Weight 174.1291
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM ANISATE

SMILES

[Na+].COC1=CC=C(C=C1)C([O-])=O

InChI

InChIKey=AETSDHMVQHOYPB-UHFFFAOYSA-M
InChI=1S/C8H8O3.Na/c1-11-7-4-2-6(3-5-7)8(9)10;/h2-5H,1H3,(H,9,10);/q;+1/p-1

HIDE SMILES / InChI

Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C8H7O3
Molecular Weight 151.1394
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

SODIUM ANISATE is derived from fennel, this is the sodium salt of p-anisic acid. It is classified as antimicrobial and flavouring. It acts as an anti-fungal agent, and when paired with sodium levulinate the two ingredients make for a comprehensive preservative for cosmetics. This ingredient is approved for use in organic cosmetics. Sodium anisate (dermosoft® anisate) is an easy to use water soluble salt of an organic acid with an excellent fungicidal activity. It can be added to the cold or hot water phase at any step of the process. The combination with antimicrobial surface active substances or organic acids is recommended to improve the performance of the product even at higher pH.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
9.9 nM [Ki]
Target ID: P00593
Gene ID: 104974671|||282457
Gene Symbol: PLA2G1B
Target Organism: Bos taurus (Bovine)
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
Inactive ingredient
Thera Wise Natural Acne

Approved Use

Helps treat acne pimples and allows skin to heal
PubMed

PubMed

TitleDatePubMed
The aniracetam metabolite 2-pyrrolidinone induces a long-term enhancement in AMPA receptor responses via a CaMKII pathway.
2002 Jan 31
Synthesis of 5,6-dimethyl-9-methoxy-1-phenyl-6H-pyrido[4,3-b]carbazole derivatives and their cytotoxic activity.
2005 Nov
Quick determination of malodor-causing fatty acids in manure by capillary electrophoresis.
2005 Sep
SanJ, an ATP-dependent picolinate-CoA ligase, catalyzes the conversion of picolinate to picolinate-CoA during nikkomycin biosynthesis in Streptomyces ansochromogenes.
2006 May
Inhibitory effect of Hemidesmus indicus and its active principle 2-hydroxy 4-methoxy benzoic acid on ethanol-induced liver injury.
2007 Oct
Purification and preliminary crystallographic analysis of a new Lys49-PLA2 from B. Jararacussu.
2008 May
Crystal structure of a ferredoxin reductase for the CYP199A2 system from Rhodopseudomonas palustris.
2009 Dec
Antioxidant and radical scavenging properties of Malva sylvestris.
2009 Jul
An updated review of tyrosinase inhibitors.
2009 May 26
Relationship correlation of antioxidant and antiproliferative capacity of Cyperus rotundus products towards K562 erythroleukemia cells.
2009 Sep 14
Variations in IC(50) values with purity of mushroom tyrosinase.
2009 Sep 2
Tetra-kis(μ-4-methoxy-benzoato)bis-[(4-methoxy-benzoato)(1,10-phenan-throline)terbium(III)].
2009 Sep 26
Bis(4-meth-oxy-benzoato)-κO,O';κO-bis-(nicotinamide-κN)zinc(II).
2010 Aug 21
2-hydroxy 4-methoxy benzoic acid isolated from roots of Hemidesmus indicus ameliorates liver, kidney and pancreas injury due to streptozotocin-induced diabetes in rats.
2010 Feb
Diaqua-bis-(4-meth-oxy-benzoato-κO)bis-(nicotinamide-κN)cobalt(II) dihydrate.
2010 Jul 10
N'-[Bis(benzyl-sulfan-yl)methyl-idene]-4-meth-oxy-benzohydrazide.
2010 Jul 3
2,5-Bis(4-meth-oxy-phen-yl)-1,3,4-oxadiazole.
2010 Nov 6
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
4-methoxy-benzoic acid inhibited β-carbonic anhydrase (EC 4.2.1.1) from the pathogenic fungi Cryptococcus neoformans (Can2) with IC50 value of 9.9 nM.
Substance Class Chemical
Created
by admin
on Thu Jul 06 11:44:16 UTC 2023
Edited
by admin
on Thu Jul 06 11:44:16 UTC 2023
Record UNII
F9WFJ28MV9
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SODIUM ANISATE
INCI  
INCI  
Official Name English
BENZOIC ACID, 4-METHOXY-, SODIUM SALT (1:1)
Common Name English
SODIUM P-ANISATE
Common Name English
SODIUM P-METHOXYBENZOATE
Common Name English
SODIUM ANISATE [INCI]
Common Name English
Code System Code Type Description
DAILYMED
F9WFJ28MV9
Created by admin on Thu Jul 06 11:44:17 UTC 2023 , Edited by admin on Thu Jul 06 11:44:17 UTC 2023
PRIMARY
RXCUI
1366968
Created by admin on Thu Jul 06 11:44:17 UTC 2023 , Edited by admin on Thu Jul 06 11:44:17 UTC 2023
PRIMARY RxNorm
EPA CompTox
DTXSID00201818
Created by admin on Thu Jul 06 11:44:17 UTC 2023 , Edited by admin on Thu Jul 06 11:44:17 UTC 2023
PRIMARY
CAS
536-45-8
Created by admin on Thu Jul 06 11:44:17 UTC 2023 , Edited by admin on Thu Jul 06 11:44:17 UTC 2023
PRIMARY
EVMPD
SUB176559
Created by admin on Thu Jul 06 11:44:17 UTC 2023 , Edited by admin on Thu Jul 06 11:44:17 UTC 2023
PRIMARY
FDA UNII
F9WFJ28MV9
Created by admin on Thu Jul 06 11:44:17 UTC 2023 , Edited by admin on Thu Jul 06 11:44:17 UTC 2023
PRIMARY
ECHA (EC/EINECS)
208-634-1
Created by admin on Thu Jul 06 11:44:17 UTC 2023 , Edited by admin on Thu Jul 06 11:44:17 UTC 2023
PRIMARY
SMS_ID
100000162655
Created by admin on Thu Jul 06 11:44:17 UTC 2023 , Edited by admin on Thu Jul 06 11:44:17 UTC 2023
PRIMARY
PUBCHEM
23663627
Created by admin on Thu Jul 06 11:44:17 UTC 2023 , Edited by admin on Thu Jul 06 11:44:17 UTC 2023
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE