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Details

Stereochemistry ACHIRAL
Molecular Formula C8H7O3.Na
Molecular Weight 174.1291
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM ANISATE

SMILES

[Na+].COC1=CC=C(C=C1)C([O-])=O

InChI

InChIKey=AETSDHMVQHOYPB-UHFFFAOYSA-M
InChI=1S/C8H8O3.Na/c1-11-7-4-2-6(3-5-7)8(9)10;/h2-5H,1H3,(H,9,10);/q;+1/p-1

HIDE SMILES / InChI

Molecular Formula C8H7O3
Molecular Weight 151.1394
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

SODIUM ANISATE is derived from fennel, this is the sodium salt of p-anisic acid. It is classified as antimicrobial and flavouring. It acts as an anti-fungal agent, and when paired with sodium levulinate the two ingredients make for a comprehensive preservative for cosmetics. This ingredient is approved for use in organic cosmetics. Sodium anisate (dermosoft® anisate) is an easy to use water soluble salt of an organic acid with an excellent fungicidal activity. It can be added to the cold or hot water phase at any step of the process. The combination with antimicrobial surface active substances or organic acids is recommended to improve the performance of the product even at higher pH.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
9.9 nM [Ki]
Target ID: P00593
Gene ID: 104974671|||282457
Gene Symbol: PLA2G1B
Target Organism: Bos taurus (Bovine)
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
Inactive ingredient
Thera Wise Natural Acne

Approved Use

Helps treat acne pimples and allows skin to heal
PubMed

PubMed

TitleDatePubMed
Biodegradation of hydroxylated and methoxylated benzoic, phenylacetic and phenylpropenoic acids present in olive mill wastewaters by two bacterial strains.
2001 Jan-Feb
Diterpenes and other constituents from Croton draco (Euphorbiaceae).
2001 Mar
Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism.
2001 May 18
Aniracetam enhances cortical dopamine and serotonin release via cholinergic and glutamatergic mechanisms in SHRSP.
2001 Oct 19
The aniracetam metabolite 2-pyrrolidinone induces a long-term enhancement in AMPA receptor responses via a CaMKII pathway.
2002 Jan 31
Determination of serum astragaloside in rats fed with Buyanghuanwu dicoction using solidphase extraction, chemical derivatization and fluorospectrophotometry.
2003 Apr
Enzyme production by Mycena galopus mycelium in artificial media and in Picea sitchensis F1 horizon needle litter.
2003 Aug
Biotransformations of propenylbenzenes by an Arthrobacter sp. and its t-anethole blocked mutants.
2003 Oct 9
Tyrosinase inhibition kinetics of anisic acid.
2003 Sep-Oct
Marmenol: a 7-geranyloxycoumarin from the leaves of Aegle marmelos Corr.
2004 Apr
Synthesis of 5,6-dimethyl-9-methoxy-1-phenyl-6H-pyrido[4,3-b]carbazole derivatives and their cytotoxic activity.
2005 Nov
Crystal structures of the complexes of a group IIA phospholipase A2 with two natural anti-inflammatory agents, anisic acid, and atropine reveal a similar mode of binding.
2006 Jul 1
[Studies on chemical constituents of cytotoxic fraction from leaves of Elaeagnus pungens].
2006 Mar
SanJ, an ATP-dependent picolinate-CoA ligase, catalyzes the conversion of picolinate to picolinate-CoA during nikkomycin biosynthesis in Streptomyces ansochromogenes.
2006 May
Antioxidant constituents of Nymphaea caerulea flowers.
2008 Jul
Chemical constituents from leaves of Palicourea coriacea (Rubiaceae).
2008 Jul
[Quantitative monitoring the concentration changes of organic acids in fermentation process of Clostridium acetobutylicum using capillary ion electrophoresis].
2008 Nov
A novel norditerpenoid alkaloid from Aconitum macrorhynchum.
2009 Aug
Variations in IC(50) values with purity of mushroom tyrosinase.
2009 Sep 2
Tetra-kis(μ-4-methoxy-benzoato)bis-[(4-methoxy-benzoato)(1,10-phenan-throline)terbium(III)].
2009 Sep 26
Influence of very low doses of mediators on fungal laccase activity - nonlinearity beyond imagination.
2009 Sep 4
Bis(4-meth-oxy-benzoato)-κO,O';κO-bis-(nicotinamide-κN)zinc(II).
2010 Aug 21
Di-μ-nicotinamide-κO:N;κN:O-bis-[aqua-bis-(4-meth-oxy-benzoato-κO)copper(II)].
2010 Jun 16
Protein recognition in ferredoxin-P450 electron transfer in the class I CYP199A2 system from Rhodopseudomonas palustris.
2010 Mar
Bis[μ-2,2'-dimethyl-1,1'-(oxydiethyl-ene)bis-(1H-benzimidazole)-κN:N]bis-[bis-(4-methoxy-benzoato-κO,O')cadmium(II)].
2010 Mar 20
New alternatives to cosmetics preservation.
2010 Mar-Apr
2,5-Bis(4-meth-oxy-phen-yl)-1,3,4-oxadiazole.
2010 Nov 6
Relationship between chemical structure and biological activity of alkali metal o-, m- and p-anisates. FT-IR and microbiological studies.
2011 Nov
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
4-methoxy-benzoic acid inhibited β-carbonic anhydrase (EC 4.2.1.1) from the pathogenic fungi Cryptococcus neoformans (Can2) with IC50 value of 9.9 nM.
Substance Class Chemical
Created
by admin
on Sat Dec 17 19:17:19 UTC 2022
Edited
by admin
on Sat Dec 17 19:17:19 UTC 2022
Record UNII
F9WFJ28MV9
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SODIUM ANISATE
INCI  
INCI  
Official Name English
BENZOIC ACID, 4-METHOXY-, SODIUM SALT (1:1)
Common Name English
SODIUM P-ANISATE
Common Name English
SODIUM P-METHOXYBENZOATE
Common Name English
SODIUM ANISATE [INCI]
Common Name English
Code System Code Type Description
DAILYMED
F9WFJ28MV9
Created by admin on Sat Dec 17 19:17:19 UTC 2022 , Edited by admin on Sat Dec 17 19:17:19 UTC 2022
PRIMARY
RXCUI
1366968
Created by admin on Sat Dec 17 19:17:19 UTC 2022 , Edited by admin on Sat Dec 17 19:17:19 UTC 2022
PRIMARY RxNorm
EPA CompTox
DTXSID00201818
Created by admin on Sat Dec 17 19:17:19 UTC 2022 , Edited by admin on Sat Dec 17 19:17:19 UTC 2022
PRIMARY
CAS
536-45-8
Created by admin on Sat Dec 17 19:17:19 UTC 2022 , Edited by admin on Sat Dec 17 19:17:19 UTC 2022
PRIMARY
EVMPD
SUB176559
Created by admin on Sat Dec 17 19:17:19 UTC 2022 , Edited by admin on Sat Dec 17 19:17:19 UTC 2022
PRIMARY
FDA UNII
F9WFJ28MV9
Created by admin on Sat Dec 17 19:17:19 UTC 2022 , Edited by admin on Sat Dec 17 19:17:19 UTC 2022
PRIMARY
ECHA (EC/EINECS)
208-634-1
Created by admin on Sat Dec 17 19:17:19 UTC 2022 , Edited by admin on Sat Dec 17 19:17:19 UTC 2022
PRIMARY
PUBCHEM
23663627
Created by admin on Sat Dec 17 19:17:19 UTC 2022 , Edited by admin on Sat Dec 17 19:17:19 UTC 2022
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE