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Details

Stereochemistry ACHIRAL
Molecular Formula C8H7O3.Na
Molecular Weight 174.1295
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM ANISATE

SMILES

COc1ccc(cc1)C(=O)[O-].[Na+]

InChI

InChIKey=AETSDHMVQHOYPB-UHFFFAOYSA-M
InChI=1S/C8H8O3.Na/c1-11-7-4-2-6(3-5-7)8(9)10;/h2-5H,1H3,(H,9,10);/q;+1/p-1

HIDE SMILES / InChI

Molecular Formula C8H7O3
Molecular Weight 151.1397
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

SODIUM ANISATE is derived from fennel, this is the sodium salt of p-anisic acid. It is classified as antimicrobial and flavouring. It acts as an anti-fungal agent, and when paired with sodium levulinate the two ingredients make for a comprehensive preservative for cosmetics. This ingredient is approved for use in organic cosmetics. Sodium anisate (dermosoft® anisate) is an easy to use water soluble salt of an organic acid with an excellent fungicidal activity. It can be added to the cold or hot water phase at any step of the process. The combination with antimicrobial surface active substances or organic acids is recommended to improve the performance of the product even at higher pH.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
9.9 nM [Ki]
Target ID: P00593
Gene ID: 104974671|||282457
Gene Symbol: PLA2G1B
Target Organism: Bos taurus (Bovine)
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
Inactive ingredient
Thera Wise Natural Acne

Approved Use

Helps treat acne pimples and allows skin to heal
PubMed

PubMed

TitleDatePubMed
[Theophylline-sodium anisate].
1955 Aug 13
Aniracetam enhances cortical dopamine and serotonin release via cholinergic and glutamatergic mechanisms in SHRSP.
2001 Oct 19
The trans-anethole degradation pathway in an Arthrobacter sp.
2002 Apr 5
Enzyme production by Mycena galopus mycelium in artificial media and in Picea sitchensis F1 horizon needle litter.
2003 Aug
Kinetics of thermal decomposition of 4-carboxyl-2,6-dinitrobenzenediazonium ion (CDNBD).
2005 Jul-Aug
Quick determination of malodor-causing fatty acids in manure by capillary electrophoresis.
2005 Sep
Third calcium ion found in an inhibitor-bound phospholipase A2.
2006 Apr
[Studies on chemical constituents of cytotoxic fraction from leaves of Elaeagnus pungens].
2006 Mar
Hypoglycemic activity of Hemidesmus indicus R. Br. on streptozotocin-induced diabetic rats.
2008 Jan
Antioxidant constituents of Nymphaea caerulea flowers.
2008 Jul
Purification and preliminary crystallographic analysis of a new Lys49-PLA2 from B. Jararacussu.
2008 May
[Quantitative monitoring the concentration changes of organic acids in fermentation process of Clostridium acetobutylicum using capillary ion electrophoresis].
2008 Nov
A novel norditerpenoid alkaloid from Aconitum macrorhynchum.
2009 Aug
Crystal structure of a ferredoxin reductase for the CYP199A2 system from Rhodopseudomonas palustris.
2009 Dec
Antioxidant and radical scavenging properties of Malva sylvestris.
2009 Jul
Home-prepared anatase, rutile, and brookite TiO(2) for selective photocatalytic oxidation of 4-methoxybenzyl alcohol in water: reactivity and ATR-FTIR study.
2009 May
An updated review of tyrosinase inhibitors.
2009 May 26
Aryl-alcohol oxidase involved in lignin degradation: a mechanistic study based on steady and pre-steady state kinetics and primary and solvent isotope effects with two alcohol substrates.
2009 Sep 11
Relationship correlation of antioxidant and antiproliferative capacity of Cyperus rotundus products towards K562 erythroleukemia cells.
2009 Sep 14
Variations in IC(50) values with purity of mushroom tyrosinase.
2009 Sep 2
Influence of very low doses of mediators on fungal laccase activity - nonlinearity beyond imagination.
2009 Sep 4
2-hydroxy 4-methoxy benzoic acid isolated from roots of Hemidesmus indicus ameliorates liver, kidney and pancreas injury due to streptozotocin-induced diabetes in rats.
2010 Feb
Diaqua-bis-(4-meth-oxy-benzoato-κO)bis-(nicotinamide-κN)nickel(II) dihydrate.
2010 Jul 7
Di-μ-nicotinamide-κO:N;κN:O-bis-[aqua-bis-(4-meth-oxy-benzoato-κO)copper(II)].
2010 Jun 16
Protein recognition in ferredoxin-P450 electron transfer in the class I CYP199A2 system from Rhodopseudomonas palustris.
2010 Mar
Bis[μ-2,2'-dimethyl-1,1'-(oxydiethyl-ene)bis-(1H-benzimidazole)-κN:N]bis-[bis-(4-methoxy-benzoato-κO,O')cadmium(II)].
2010 Mar 20
New alternatives to cosmetics preservation.
2010 Mar-Apr
Bis[μ-2,2'-dimethyl-1,1'-(3-oxapentane-1,5-di-yl)di-1H-benzimidazole-κN:N]bis-[bis-(4-meth-oxy-benzoato)-κO;κO,O'-cobalt(II)].
2010 Nov 13
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
4-methoxy-benzoic acid inhibited β-carbonic anhydrase (EC 4.2.1.1) from the pathogenic fungi Cryptococcus neoformans (Can2) with IC50 value of 9.9 nM.
Substance Class Chemical
Created
by admin
on Sat Jun 26 16:34:26 UTC 2021
Edited
by admin
on Sat Jun 26 16:34:26 UTC 2021
Record UNII
F9WFJ28MV9
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SODIUM ANISATE
INCI  
INCI  
Official Name English
BENZOIC ACID, 4-METHOXY-, SODIUM SALT (1:1)
Common Name English
SODIUM P-ANISATE
Common Name English
SODIUM P-METHOXYBENZOATE
Common Name English
SODIUM ANISATE [INCI]
Common Name English
Code System Code Type Description
RXCUI
1366968
Created by admin on Sat Jun 26 16:34:27 UTC 2021 , Edited by admin on Sat Jun 26 16:34:27 UTC 2021
PRIMARY RxNorm
EPA CompTox
536-45-8
Created by admin on Sat Jun 26 16:34:27 UTC 2021 , Edited by admin on Sat Jun 26 16:34:27 UTC 2021
PRIMARY
CAS
536-45-8
Created by admin on Sat Jun 26 16:34:27 UTC 2021 , Edited by admin on Sat Jun 26 16:34:27 UTC 2021
PRIMARY
EVMPD
SUB176559
Created by admin on Sat Jun 26 16:34:27 UTC 2021 , Edited by admin on Sat Jun 26 16:34:27 UTC 2021
PRIMARY
FDA UNII
F9WFJ28MV9
Created by admin on Sat Jun 26 16:34:27 UTC 2021 , Edited by admin on Sat Jun 26 16:34:27 UTC 2021
PRIMARY
ECHA (EC/EINECS)
208-634-1
Created by admin on Sat Jun 26 16:34:27 UTC 2021 , Edited by admin on Sat Jun 26 16:34:27 UTC 2021
PRIMARY
PUBCHEM
23663627
Created by admin on Sat Jun 26 16:34:27 UTC 2021 , Edited by admin on Sat Jun 26 16:34:27 UTC 2021
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE