SCH-51866

Details

Stereochemistry	RACEMIC
Molecular Formula	C19H18F3N5O
Molecular Weight	389.3743
Optical Activity	( + / - )
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN1C2=N[C@@H]3CCC[C@@H]3N2C4=C(N=C(CC5=CC=C(C=C5)C(F)(F)F)N4)C1=O

InChI

InChIKey=JOSMPBVYYKRYLG-OLZOCXBDSA-N

InChI=1S/C19H18F3N5O/c1-26-17(28)15-16(27-13-4-2-3-12(13)23-18(26)27)25-14(24-15)9-10-5-7-11(8-6-10)19(20,21)22/h5-8,12-13H,2-4,9H2,1H3,(H,24,25)/t12-,13+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C19H18F3N5O
Molecular Weight	389.3743
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
cGMP-phosphodiesterase antagonists inhibit Ca2+-influx in Dictyostelium discoideum and bovine cyclic-nucleotide-gated-channel.	2005-04-18	15878705
Identification of human PDE7B, a cAMP-specific phosphodiesterase.	2000-05-19	10814504
Cloning and characterization of PDE7B, a cAMP-specific phosphodiesterase.	2000-01-04	10618442
Isolation and characterization of PDE9A, a novel human cGMP-specific phosphodiesterase.	1998-06-19	9624146
Antiplatelet and antiproliferative effects of SCH 51866, a novel type 1 and type 5 phosphodiesterase inhibitor.	1996-12	8961086

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:18:39 GMT 2025` Edited by `admin` on `Mon Mar 31 22:18:39 GMT 2025`
Record UNII	F8GU4PSP29
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SCH-51866

Common Name

English

CYCLOPENT(4,5)IMIDAZO(2,1-B)PURIN-4(1H)-ONE, 5,6A,7,8,9,9A-HEXAHYDRO-5-METHYL-2-((4-(TRIFLUOROMETHYL)PHENYL)METHYL)-, (6AR,9AS)-REL-

Preferred Name

English

Code System Code Type Description

CAS

167298-74-0