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Details

Stereochemistry ACHIRAL
Molecular Formula C8H11NO2
Molecular Weight 153.1784
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ENBUCRILATE

SMILES

CCCCOC(=O)C(=C)C#N

InChI

InChIKey=JJJFUHOGVZWXNQ-UHFFFAOYSA-N
InChI=1S/C8H11NO2/c1-3-4-5-11-8(10)7(2)6-9/h2-5H2,1H3

HIDE SMILES / InChI

Molecular Formula C8H11NO2
Molecular Weight 153.1784
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Enbucrilate (also known as n-butyl-cyanoacrylate, n-BCA) is an adhesive substance, which is used under different trade names (Histoacryl, 3M Liquid Bandage, etc) as an OTC medication for strong and secure wound closure. In 2000 FDA approved enbucrilate (TRUFILL n-BCA Liquid Embolic System) for presurgical embolization of cerebral arteriovenous malformations.

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
TRUFILL
Primary
3M LIQUID BANDAGE

Doses

PubMed

Sample Use Guides

In Vivo Use Guide
Topical: Apply the medication to the wound very sparingly, either as minute drops or as a very thin film along the edges of the wound. Infusion: A mixture of enbucrilate with Ethiodized Oil and tantalum powder (enbucrilate/Ethiodized oil ratio is 3:1, 2:1, 1:1, 1:2) is administered via a catheter.
Route of Administration: Other
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
F8CEP82QNP
Record Status Validated (UNII)
Record Version